Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
New Technologies to Dissect the Stem Cells-Niche Interactions
Discussion Leader: Francesco Cambuli (Columbia University, USA)
3:45 pm - 4:05 pm
Sharif Iqbal (University of Helsinki, Finland)
"Age-Induced Alterations in the ECM Reduce Regenerative Capacity of Intestinal Epithelium"
4:05 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
Zhe Ying (Fred Hutchinson Cancer Research Center, USA)
"Targeting of Long-Term Mammary Progenitors to Identify Drivers of Breast Cancer"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Where Proliferation Rules: High Turnover Tissues and Their Niches
Discussion Leader: Carien Niessen (University of Cologne, Germany)
7:30 pm - 7:50 pm
Brett Shook (Yale University, USA)
"Dermal Adipocyte Lipolysis Is Required for Multiple Aspects of Skin Regeneration"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Mara Martin Alonso (Norwegian University of Science and Technology, Norway)
"Smooth Muscle-Specific Mmp17 (Mt4-mmp) Regulates Intestinal Inflammatory and Regenerative Responses"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Ashley Jackson (Nationwide Children's Hospital, USA)
"Ontogeny of Renal Urothelial Cells During Development and Urinary Tract Obstruction"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Wan-Jin Lu (Stanford University, USA)
"Hedgehog and Good Taste: Maintenance and Regeneration of the Taste Organ in the Adult Tongue"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Slow and Steady: To Maintain and Repair
Discussion Leader: Leanne Jones (University of California, Los Angeles, USA)
9:00 am - 9:20 am
Yulia Shwartz (Harvard University, USA)
"Beyond Goosebumps: Sympathetic Innervation Regulates Hair Follicle Regeneration"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Chaoqun Wang (University of California, San Francisco, USA)
"Hedgehog Expansion Disrupts the Alveolar Niche and Induces Emphysema"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Hadas Sibony-Benyamini (Bar-Ilan University, Israel)
"HDAC1/2 Activity in the Mesenchymal Niche of the Hair Follicle Regulates Progenitor and Stem Cell Behavior During the Hair Cycle"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
David Castillo-Azofeifa (University of California, San Francisco, USA)
"Atoh1+ Secretory Progenitors Show Cellular Plasticity Essential for Colonic Regeneration in Absence of Lgr5+ Stem Cells"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Picking and Funding a Project
Discussion Leader: Margherita Paschini (Boston Children's Hospital, USA)
1:30 pm - 2:30 pm
Panel Discussion
Picking and Funding a Project
Frederic de Sauvage (Genentech, USA)
Leanne Jones (University of California, Los Angeles, USA)
Carien Niessen (University of Cologne, Germany)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
