Sunday June 13, evening |
Cell Cycle |
7:30 P.M. - 10:00 P.M. |
Marc Kirschner, Discussion Leader |
- Marc Kirschner, Harvard Medical School
"In and out of mitosis"
- Jim Roberts, Fred Hutchinson Cancer Center
"Inhibitors of the G1/S phase of the cell cycle: their role in cell proliferation and human cancers"
- Helen Piwnica-Worms, Washington University School of Medicine
"Regulation of the eukaryotic cell cycle: mitotic- and G2 checkpoint-control"
- Steve Elledge, Baylor College of Medicine
"DNA damage responses in mammalian cells"
- Short Talk: Barbara Panning, MIT (Sharp/jaenisch)
"Xist RNA and the cell cycle"
Monday June 14, morning |
Cell Polarity |
9:00 A.M. - 12:00 P.M. |
Ira Herskowitz, Discussion Leader |
- Ira Herskowitz, University of California - San Francisco
"Polarity and asymmetry in a single cell: the relationship between structure and function"
- Alan Hall, MRC Laboratory for Molecular Cell Biology, University College London
"Coordinated control of the actin cytoskeleton and gene transcription by the Rho family of small GTPases"
- James Nelson, Stanford University School of Medicine
"Cues for cellular asymmetry in polarized epithelial cells"
- Norbert Perrimon, Harvard Medical School
"Frizzled signaling and the control of cell polarity in Drosophila"
- Short Talk: Heike Fölsch, Yale University (Ira Mellman)
"µ1B, a novel component of AP1, mediates basolateral sorting in polarized epithelial cells"
Monday June 14, evening |
Cell Movement and Migration |
7:30 P.M. - 10:00 P.M. |
Peter Sorger, Discussion Leader |
- Peter Sorger, Massachusetts Insitute of Technology
"Building a simple kinetochore"
- Larry Goldstein, University of California - San Diego
"Molecular genetics of intracellular movement"
- Julie Theriot, Stanford University
"Control of actin polymerization by intracellular bacterial pathogens"
- Rachel Kindt, University of California - San Francisco (Cynthia Kenyon)
"Signals that guide migrating neuroblasts along the A/P body axis of C. elegans"
- Short Talk: Carole Parent, Johns Hopkins University (Peter Devreotes)
"Chemoattractant sensing in eukaryotic cells"
Tuesday June 15, morning |
Integrins and Extracellular Matrix |
9:00 A.M. - 12:00 P.M. |
Joan Brugge, Discussion Leader |
- Joan Brugge, Harvard Medical School
"Signal transduction events regulated by integrin adhesion receptors"
- Fiona Watt, Imperial Cancer Research Fdn.
"Integrins, stem cells and epidermal differentiation"
- Mike Sheetz, Duke University Medical Center
"Membrane tension control of endocytosis and cell migration"
- Richard Scheller, Stanford University
"Molecular mechanisms of membrane traffic and exocytosis"
- Short Talk: Daniel Kalman, University of California, San Francisco (J. Michael Bishop)
"The Wiskott-Aldrich Syndrome family of proteins and the Arp2/3 complex participate in Actin Pedestal Formation initiated by Enteropathogenic E. coli"
4:00 P.M. - 6:00 P.M. Poster Session
Tuesday June 15, evening |
Cell Biology and Disease |
7:30 P.M. - 10:00 P.M. |
Elaine Fuchs, Discussion Leader |
- Elaine Fuchs, University of Chicago
"Genetic disorders of the cytoskeleton"
- Bruce Spiegelman, Dana Farber Cancer Institute and Harvard Medical School
"Regulation of adipogenesis and energy balance by PPAR γ
and novel coactivators"
- Christine Seidman, Harvard Medical School
"Genes that pattern the heart"
- Dan Littman, New York University
"Chemokine receptors: functions in AIDS, inflammation, and development"
- Short Talk: Li-Huei Tsai, Harvard medical School
"Regulation of the cerebral cortex assembly by cyclin dependent kinase 5"
Wednesday June 16, morning |
Cell Death and Life |
9:00 A.M. - 12:00 P.M. |
Martin Raff, Discussion Leader |
- Martin Raff, MRC Laboratory for Molecular Cell Biology, University College London
"Cell number control: intrinsic and extrinsic controls on cell division and survival"
- Matthew Vander Heiden, University of Chicago (Craig Thompson)
"Molecular basis for apoptosis in response to growth factor deprivation"
- Virginia Zakian, Princeton University
"The Pif1p proteins, a conserved family of helicases that affect telomeres"
- Joan Massague, Memorial Sloan Kettering Cancer Center
"Signal transduction by TGFß family members"
- Short Talk: Scott Boyd, MIT (Tyler Jacks)
"Control of p53 localization by HDM2 and p14ARF"
Wednesday June 16, evening |
Intracellular Transport |
7:30 P.M. - 10:00 P.M. |
Jennifer Lippincott-Schwartz, Discussion Leader |
- Jennifer Lippincott-Schwartz, National Institutes of Health
"Real time analysis of secretory membrane traffic"
- Peter Walter, University of California - San Francisco
"Intracellular signaling from the ER to the nucleus"
- Randy Schekman, University of California - Berkeley
"Protein sorting into transport vesicles"
- Larry Gerace, Scripps Research Institute
"Nuclear import and export"
- Short Talk: Kent Matlack, Harvard Medical School (Tom Rapoport)
"BiP as a ratchet in prepro-α-factor translocation into the ER"
Thursday June 17, morning |
Cell Biology of the Immune System |
9:00 A.M. - 12:00 P.M. |
Ira Mellman,, Discussion Leader |
- Ira Mellman, Yale University School of Medicine
"The cell biology of antigen presentation: controlling the immune response by controlling MHC transport in dendritic cells"
- Pamela Bjorkman, California Institute of Technology
"MHC homologs in immune recognition"
- Gerry Crabtree, Stanford University Medical Center
"The interface of signal transduction and chromatin regulation"
- Laurie Glimcher, Harvard School of Public Health & Harvard Medical School
"Genetic programs in T helper cell development"
- Short Talk: Kendra Bowman, University of California, Berkeley (Carolyn Bertozzi)
"Carbohydrate sulfation and the initiation of the inflammatory response"
4:00 P.M. - 6:00 P.M. Poster Session
6:00 P.M. - 7:30 P.M. Banquet
Thursday June 17, evening |
Chemistry and Cell Biology |
7:30 P.M. - 10:00 P.M. |
Kevan Shokat, Discussion Leader |
- Kevan Shokat, Princeton University
"New chemical approaches to tracing cellular signal transduction cascades"
- Laura Kiessling, University of Wisconsin, Madison
"Controlling cell surface display with synthetic ligands"
- Tracy Handel, University of California - Berkeley
"Chemokine structure and their interactions with cell membrane proteins"
- Peter Kim, Whitehead Institute, Massachusetts Institute of Technology
"Coiled Coils as Probes of Biological Processes"
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