SUNDAY |
4:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Historical Highlights of 25 Years of PRL Family GRC Meetings |
| Discussion Leader: Arthur Gutierrez-Hartmann |
7:30 pm - 8:15 pm | Frank Talamantes
"PRL family ligand biology: The past 25 years" |
8:15 pm - 8:30 pm | Discussion |
8:30 pm - 9:15 pm | Paul Kelly
"PRL family receptor biology: The past 25 years" |
9:15 pm - 9:30 pm | Discussion |
9:30 pm | Welcome Reception |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | PRL & GH Receptors |
| Discussion Leader: Vincent Goffin (France) |
9:00 am - 9:25 am | Michael Waters (Australia)
"GH receptors from the membrane to the nucleus" |
9:25 am - 9:30 am | Discussion |
9:30 am - 9:55 am | John Kopchick (USA)
"Transgenic approaches to understanding GH action" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee break / Group Photo (10:15 am) |
10:30 am - 10:55 am | Anthony Kossiakoff (USA)
"Role of molecular adaptation and allostery in GH receptor homodimerization" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Chuck Clevenger (USA)
"PRL and its receptors: From the membrane to the nucleus" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Platform 1 and 2 talks |
11:30 am - 11:45 am | Birthe Kragelund (Denmark)
"Solution structure of human prolactin" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Matthew LeBaron (USA)
"Functional identification of PRL and GH target cells in rat tissues" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:30 pm | Overview Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:00 pm | PRL & GH Intracellular Signaling |
| Discussion Leader: Li Yu-Lee (USA) |
7:30 pm - 7:55 pm | Jorge Martin-Perez (Spain)
"Src is a key effector of PRL signaling" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:25 pm | Stuart Frank (USA)
"New leads in GH signaling" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Barbara Vonderhar (USA)
"Prolactin and its receptors in human breast cancer" |
8:55 pm - 9:00 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | PRL/GH-Induced Gene Regulation |
| Discussion Leader: Shlomo Melmed (USA) |
9:00 am - 9:25 am | Lothar Hennighausen (USA)
"Physiological insights gained from tissue-specific inactivation of STAT genes" |
9:25 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Gunnar Norstedt (Sweden)
"GH regulated gene programs in the liver" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee break |
10:30 am - 10:55 am | Iain C. Robinson (Great Britain)
"Hypothalamic mechanisms regulating somatotrope biology" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:25 am | David Waxman (USA)
"GH regulation of liver sexual dimorphism: New insights from mouse knockout models" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Platform 1 and 2 talks |
11:30 am - 11:45 am | Sabrina Semprini (UK)
"In vivo imaging of of gene expression in transgenic rats bearing a PRL-luciferase BAC transgene" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Stanko Stojilkovic (USA)
"Calcium-dependent and -independent control of basal PRL release" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:30 pm | Overview Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:00 pm | PRL Family Gene Transcription |
| Discussion Leader: Marc Freeman (USA) |
7:30 pm - 7:55 pm | Richard Day (USA)
"Imaging molecular interactions in living pituitary cells" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:25 pm | Cheryl Watson (USA)
"The control of prolactin release by multiple physiological estrogens and xenoestrogens via nongenomic mechanisms" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Michael Soares (USA)
"The prolactin family and adaptations to pregnancy" |
8:55 pm - 9:00 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | PRL/GH Target Organs |
| Discussion Leader: Nira Ben-Jonathan (USA) |
9:00 am - 9:25 am | Kay-Uwe Wagner (USA)
"PRL action in normal and neoplastic mammary gland" |
9:25 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Linda Schuler (USA)
"PRL signals in mammary neoplasia" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee break |
10:30 am - 10:55 am | Serge Y. Fuchs (USA)
"Phosphorylation-dependent ubiquitination and degradation of PRL receptor" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Steven Swanson (USA)
"GH signaling in neoplastic transformation of mammary glands in organ culture" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Platform 1 and 2 talks |
11:30 am - 11:45 am | Steven Anderson (USA)
"Lactation defects in Src -/- mice: Decreased production of milk proteins" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Suhad Ali (Canada)
"Role of PRL as an Invasion suppressor hormone in breast cancer" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:30 pm | Overview Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:00 pm | PRL & GH Ligands |
| Discussion Leader: Nancy Cooke (USA) |
7:30 pm - 7:55 pm | Ameae Walker (USA)
"Functions of pseudophosphorylated S179D prolactin" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:25 pm | Carmen Clapp (Mexico)
"16K-PRL is a natural inhibitor of angiogenesis and vasodilation in the retina" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Chris Ormandy (Australia)
"Mammary gland transcriptome in PRL receptor KO mice" |
8:55 pm - 9:00 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Pituitary Development & Tumorigenesis |
| Discussion Leader: Michael Thorner (USA) |
9:00 am - 9:25 am | Shareen Ezzat (Canada)
"FGF receptor isoforms and pituitary tumorigenesis" |
9:25 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Eduardo Arzt (Argentina)
"The role of cytokines in pituitary tumorigenesis" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee break |
10:30 am - 10:55 am | Patrice Mollard (France)
"Cellular networks within the pituitary" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Robert Osamura (Japan)
"Molecular pathogenesis of pituitary tumors" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Platform 1 and 2 talks |
11:30 am - 11:45 am | Ning-Ai Liu (USA)
"PRL receptor signaling mediates the osmotic response of embryonic zebrafish lactotrophs" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Isabelle Fernandez (France)
"A new mechanism for the generation of anti-angiogenic 16K prolactin by secreted cathepsin D" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Ingrid Struman (Belgium)
"Identification of antiangiogenic sub-peptides in the 16K fragments of the PRL/GH family" |
12:20 pm - 12:30 pm | Overview Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:00 pm | Keynote Session |
| Discussion Leader: Hallgeir Rui |
7:30 pm - 8:30 pm | Sally Camper (USA)
"Molecular mechanisms regulating pituitary ontogeny" |
8:30 pm - 9:00 pm | Overview Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |