SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | WATER AND MEMBRANE PERMEABILITY |
| Chair: Steve White (UC Irvine) Discussion Leader: Hemi Gutman (Tel Aviv, Israel) |
7:30 pm | Chair's Remarks |
7:40 pm - 8:10 pm | Tom Haines (CCNY)
"Lipid structures and proton movements in membranes: cardiolipin, polyisoprenes and sterols" |
8:10 pm - 8:40 pm | Gerhard Hummer (NIH)
"Water and proton transport through hydrophobic channels: From nanotubes to proteins" |
8:40 pm - 9:10 pm | Bob Stroud (UCSF)
"Aquaglyceroporins: molecular descriptions of function" |
9:10 pm | General Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Conference Photo |
9:00 am - 12:30 pm | PORES & CHANNELS |
| Chair: Larry Pinto (Northwestern)
Discussion Leader: Régis Pomès (Toronto, Canada) |
9:00 am | Chair's Remarks |
9:10 am - 9:40 am | Greg Voth (Utah)
"Molecular dynamics simulations of proton channels" |
9:40 am - 10:10 am | Sam Cukierman (Loyola)
"Proton transfer in semi-synthetic gramicidin channels: modulation via lipid-protein interactions" |
10:10 am | Coffee Break |
10:50 am - 11:20 am | Lise Heginbotham (Yale)
"Functional studies on the KcsA channel" |
11:20 am - 11:50 am | Raimund Dützler (Rockefeller)
"X-ray structure of a ClC chloride channel: insight into the molecular basis of anion selectivity" |
11:50 am | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | GATED CHANNELS |
| Chair: Tom DeCoursey (Rush Medical Center)
Discussion Leader: Dan Minor (UCSF) |
7:30 pm | Chair's Remarks |
7:40 pm - 8:10 pm | Francisco Bezanilla (UCLA)
"Proton transport by a voltage sensor" |
8:10 pm - 8:40 pm | Mark Sansom (Oxford, UK)
"Simulations of channel function and gating" |
8:40 pm - 9:10 pm | Bob Guy (NIH)
"Molecular modeling of ion channels from crystal structures:
the mechanosensitive channel MscL" |
9:10 pm | General Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | PUMPS & ATPASES |
| Chair: Bob Fillingame (Wisconsin)
Discussion Leader: Gene Scarborough (UNC Chapel Hill) |
9:00 am | Chair's Remarks |
9:10 am - 9:40 am | John Walker (Cambridge, UK)
"F and V-type ATPases" |
9:40 am - 10:10 am | David Stokes (NYU)
"Structural snapshots of ATP-dependent transport by Ca-ATPase" |
10:10 am | Coffee Break |
10:50 am - 11:20 am | Baz Jackson (Birmingham, UK)
"Proton translocation by transhydrogenase" |
11:20 am - 11:50 am | Philip Thomas (UTSW)
"Function and dysfunction of ABC transporters" |
11:50 am | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | COUPLED TRANSPORTERS |
| Chair: Ron Kaback (UCLA)
Discussion Leader: Pete Henderson (Leeds, UK) |
7:30 pm | Chair's Remarks |
7:40 pm - 8:10 pm | Terry Krulwich (Mount Sinai School of Medicine, NY)
"Pivotal roles for the motif C of tetracycline efflux proteins" |
8:10 pm - 8:40 pm | Janet Wood (U. Guelph, Canada)
"Osmosensory mechanism of H+-osmoprotectant symporter ProP from Escherichia coli" |
8:40 pm - 9:10 pm | Gary Rudnick (Yale)
"SERT - a transporter not coupled to protons" |
9:10 pm | General Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ELECTRON/PROTON COUPLING I |
| Chair: Bob Cukier (Michigan)
Discussion Leader: Uli Brandt (Frankfurt, Germany) |
9:00 am | Chair's Remarks |
9:10 am - 9:40 am | Fabrice Rappaport (Paris, France)
"H+/e- coupling in O2 evolution" |
9:40 am - 10:10 am | Roy Lancaster (Frankfurt, Germany)
"Coupled transmembrane proton and electron transfer in the dihaem-containing quinol:fumarate reductase from Wolinella succinogenes" |
10:10 am | Coffee Break |
10:50 am - 11:20 am | Mark Paddock (UCSD)
"H+/e- coupling in bacterial reaction centers" |
11:20 am - 11:50 am | Peter Brzezinski (Stockholm, Sweden)
"Proton pumping by cytochrome oxidase" |
11:50 am | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | ELECTRON/PROTON COUPLING II |
| Chair: Shinya Yoshikawa (Himeji Inst, Japan)
Discussion Leader: Bob Gennis (Illinois) |
7:30 pm | Chair's Remarks |
7:40 pm - 8:10 pm | Marilyn Gunner (CCNY)
"Electrostatics in membrane proteins" |
8:10 pm - 8:40 pm | Pete Rich (London, UK)
"ATR-FTIR spectroscopy studies of respiratory complexes" |
8:40 pm - 9:10 pm | Alexei Stuchebrukhov (UC Davis)
"Electron transfer reactions coupled to proton translocation and proton pumping mechanisms" |
9:10 pm | General Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | RHODOPSINS |
| Chair: Judith Herzfeld (Brandeis)
Discussion Leader: John Spudich (Texas) |
9:00 am | Chair's Remarks |
9:10 am - 9:40 am | Hudel Luecke (UC Irvine)
"Light-driven ion-pumping and signaling in bacterial rhodopsins" |
9:40 am - 10:10 am | Joachim Heberle (Jülich, Germany)
"Proton pumping in proteorhodopsin from marine plankton, a functional relative of bacteriorhodopsin" |
10:10 am | Coffee Break |
10:50 am - 11:20 am | Dieter Oesterhelt (Martinsried, Germany)
"Structure of halorhodopsin and its photocycle intermediates" |
11:20 am - 11:50 am | Javier Navarro (UTMB)
"Visual rhodopsin" |
11:50 am | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | SALUTE TO HEMI GUTMAN |
| Chair: Olof Einarsdottir (UCSC)
Discussion Leader: Dave Deamer (UCSC) |
7:30 pm | Chair's Remarks |
7:40 pm - 8:10 pm | Ernst Bamberg (Frankfurt, Germany)
"Vectoriality and channel properties of proteorhodopsin and channelopsin" |
8:10 pm - 8:40 pm | Wolfgang Junge (Osnabrück, Germany)
"The rotary mechanics of H+-ATPase" |
8:40 pm - 9:10 pm | Hemi Gutman (Tel Aviv, Israel)
"Anatomy of the spherical cow approximation" |
9:10 pm | General Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |