Gordon Research Conferences
Meeting Details

Gordon Research Conference

The Body Electric: Understanding the Role of Endogenous Electric Fields in Development, Regeneration and Cancer and Utilizing Electric Fields to Treat Diseases


July 1-6, 2012


Renaissance Tuscany Il Ciocco
Lucca (Barga), Italy


Christine E. Pullar

Vice Chair:
David A. Dean

Meeting Description

The 2012 Gordon Research Conference on Bioelectrochemistry will present cutting-edge research on the body electric: understanding the role of endogenous electric fields in development, regeneration and cancer and utilizing electric fields to treat diseases. The Conference will feature a wide range of topics, such as: the role of voltage gradients and endogenous electric fields in development and regeneration; sensing electric fields/voltage; the use of endogenous EFs/ionic flow and EF pulses in the detection and treatment of cancer/diseases; modeling/techniques and biosensors for the in vivo study of bioelectricity; biological responses to nanosecond and picosecond pulses; electroporation and the brain - responses and imaging; DNA electroporation and immunity - modulation of the immune response by and in response to electroporation; the cell biology of gene transfer - during and after the pulse and the final hot topics session.

Invited speakers are experts in the field of bioelectrochemistry and the related specialties of biophysics, cell biology, developmental biology, electrochemistry, bioelectromagnetics, and medicine as they relate to the effects of weak and strong electric fields on membranes, cells, and tissues. The Conference will bring together a collection of investigators who are at the forefront of their field, and will provide opportunities for junior scientists and graduate students to present their work at both the GRS and the GRC in poster format and exchange ideas with leaders in the field. Some poster presenters will be selected for short talks within the GRS or the GRC. The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promotes cross-disciplinary collaborations in the various research areas represented.

Related Meeting

This GRC was held in conjunction with the "Bioelectrochemistry" Gordon Research Seminar (GRS). Refer to the associated GRS program page for more information.


Meeting Program

4:00 pm - 8:00 pmArrival and Check-in (Check-in Desk Closed 6:00 pm - 7:45 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmElectroporation And The Brain - Responses And Imaging
Discussion Leader: Julie Gehl (University of Copenhagen)
7:40 pm - 8:20 pmRafael Davalos (Virginia Tech)
"Recent advances in the use of irreversible electroporation for the treatment of brain cancer"
8:20 pm - 8:35 pmDiscussion
8:35 pm - 9:05 pmFaisal Mahmood (University of Copenhagen)
"Electroporation in the brain - developing methods for delivery and verification"
9:05 pm - 9:20 pmDiscussion
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmThe Role Of Voltage Gradients And Endogenous Electric Fields In Development And Regeneration
Discussion Leader: Ann Rajnicek (University of Aberdeen)
9:00 am - 9:40 amMike Levin (Tufts University)
"Transmembrane voltage gradients as patterning signals in vivo"
9:40 am - 10:00 amDiscussion
10:00 amGroup Photo / Coffee Break
10:30 am - 11:10 amNestor Oviedo (University of California Merced)
"Rational modulation of stem cell behavior by targeting signaling pathways"
11:10 am - 11:30 amDiscussion
11:30 am - 12:10 pmJoaquin Rodriguez-Léon (University of Extremadura)
"pH dynamics as a temporal regulator of fin regeneration"
12:10 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session - all posters up for viewing
5:30 pm - 7:30 pmBiological Responses To Nanosecond And Picosecond Pulses
Discussion Leader: Damijan Miklavcic (University of Ljubljana)
5:30 pm - 5:55 pmAndrei Pakhomov (Old Dominion University)
"Cellular effects of nanosecond pulses"
5:55 pm - 6:10 pmDiscussion
6:10 pm - 6:35 pmKen-ichi Yano (Kumamoto University)
"Nanosecond pulsed electric fields act as a novel form of cellular stress to induce translational suppression in human cells"
6:35 pm - 6:50 pmDiscussion
6:50 pm - 7:15 pmTom Vernier (University of Southern California)
"Conductance of single pores in electropermeabilized membranes - experimental observations and molecular models"
7:15 pm - 7:30 pmDiscussion
8:00 pmDinner
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMechanisms For Sensing Electric Fields/voltage
Discussion Leader: Colin McCaig (University of Aberdeen)
9:00 am - 9:30 amMatias Simons (University Hospital Freiburg)
"The role of pH regulation in cell polarity and electrotaxis"
9:30 am - 9:45 amDiscussion
9:45 am - 10:00 amMaria Lobikin (Tufts University)
"Mechanisms of serotonergic signal transduction of bioelectrically-induced neoplasia"
10:00 am - 10:10 amDiscussion
10:10 amCoffee Break
10:30 am - 11:10 amHans-Hermann Gerdes (University of Bergen)
"Tunneling nanotubes: biogenesis and role in long-distance electrical signaling"
11:10 am - 11:30 amDiscussion
11:30 am - 12:10 pmYasushi Okamura (Osaka University)
"Secret lives of Voltage-Sensing Phosphatases"
12:10 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session - authors will present odd-numbered posters
5:30 pm - 7:30 pmThe Cell Biology Of Gene Transfer - During And After The Pulse
Discussion Leader: Justin Teissie (CNRS / University of Toulouse)
5:30 pm - 6:15 pmMarie-Pierre Rols (CNRS/ University of Toulouse)
"Life Imaging of DNA Electrotransfer"
6:15 pm - 6:30 pmDiscussion
6:30 pm - 7:15 pmJustin Teissie (CNRS/University of Toulouse)
"The DNA-Cell Complex During and After the Pulse"
7:15 pm - 7:30 pmDiscussion
8:00 pmDinner
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmIonic Flow/electric Fields In The Treatment Of Cancer/diseases
Discussion Leader: Lluis Mir (Institute Gustave-Roussy)
9:00 am - 9:25 amRichard Nuccitelli (BioElectroMed)
"External and internal tumor ablation using 100 ns pulsed electric fields"
9:25 am - 9:40 amDiscussion
9:40 am - 10:00 amMattia Ronchetti (IGEA)
"Electrochemotherapy in bone metastasis: preclinical and clinical experience"
10:00 am - 10:10 amDiscussion
10:10 amCoffee Break
10:30 am - 11:10 amMustafa Djamgoz (Imperial College of Science)
"Electrical signaling in cancer cells: from basic electrobiochemistry to clinic"
11:10 am - 11:30 amDiscussion
11:30 am - 12:10 pmYoram Palti (Novo-cure)
"Treating cancer with alternating electric fields; mechanisms of tumor cell destruction and clinical experience"
12:10 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session - all posters up for viewing
5:30 pm - 7:30 pmDNA Electroporation And Immunity
Discussion Leader: Richard Heller (Old Dominion University)
5:30 pm - 6:00 pmEmanuela Signori (CNR - Institute of Translational Pharmocolgy)
"The important role of electroporation in DNA vaccination protocols"
6:00 pm - 6:15 pmDiscussion
6:15 pm - 6:45 pmUta Griesenbach (Imperial College of Science)
"Moving forward with cystic fibrosis gene therapy"
6:45 pm - 7:00 pmDiscussion
7:00 pm - 7:20 pmNiranjan Y. Sardesai (Inovio Pharmaceuticals)
"Surface EP development and modulation of electric field strengths to achieve selective and highly focused immune responses"
7:20 pm - 7:30 pmDiscussion
7:30 pm - 8:00 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
8:00 pmDinner
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmModelling/Techniques/Biosensors For The In Vivo Study Of Bioelectricity
Discussion Leader: Frank Hart (The University of the South)
9:00 am - 9:40 amDany Adams (Tufts University)
"Using fluorescent bioelectricity reporters to measure stable, ion-flux dependent phenomena in vivo: general principles and examples"
9:40 am - 10:00 amDiscussion
10:00 amCoffee Break
10:30 am - 11:00 amHidekatzu Tsutsui (Osaka University)
"FRET sensing of membrane potential"
11:00 am - 11:20 amDiscussion
11:20 am - 11:40 amBrook Chernet (Tufts University)
"Bioelectric detection and control of carcinogenesis in vivo"
11:40 am - 11:55 amDiscussion
11:55 am - 12:15 pmLluis Mir (Institute Gustave-Roussy)
"Electroporation and electropermeabilization"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session - authors will present even-numbered posters
5:30 pm - 7:30 pmHot Topics
Discussion Leader: David Dean (University of Rochester)
5:30 pm - 6:10 pmJulie Gehl (University of Copenhagen)
"Drug and gene delivery by electroporation. Are Doctors going electric?"
6:10 pm - 6:30 pmDiscussion
6:30 pm - 7:10 pmAnn Rajnicek (University of Aberdeen)
"Nerve growth and guidance on electrically conductive materials"
7:10 pm - 7:30 pmDiscussion
8:00 pmDinner
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Funding for this conference was made possible (in part) by 1R13 EB015764-01 from the National Institute of Biomedical Imaging and Bioengineering. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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