Gordon Research Conferences
Meeting Details
Search:
  GO

Protons & Membrane Reactions
Gordon Research Conference

Dates

February 19-24, 2012

Location

Four Points Sheraton / Holiday Inn Express
Ventura, CA

Organizers

Chair:
Marilyn Gunner

Vice Chair:
Stephen H. White

Meeting Description

The 2012 Gordon Conference on Protons & Membrane Reactions will bring together cutting edge research on the transport of proton, electrons, ions and water through proteins in biological membranes. Topics will consider the structure of membranes and membrane proteins and the thermodynamics and kinetics of transport. The aim will be to better understand the functions of biological energy transduction, sensory perception, nerve conduction and signaling that rely on active and passive transport of solutes, proton and electron transport. This interdisciplinary meeting brings together scientists carrying out studies ranging from the interactions of ions with water and membranes to the biology of channel, transporters and electron transfer proteins. Experimental and theoretical approaches will be brought together to understand basic principles of membrane transport processes. The conference will provide an opportunity for young researchers to present their results and discuss science with more established colleagues. The GRC on Protons & Membrane Reactions encourages presentations in the form of posters, which play a vital role in the meeting discourse.

Contributors

Meeting Program

SUNDAY
4:00 pm - 8:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:45 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmProtons charging the membrane
7:40 pm - 7:55 pm Session Chair: Shelagh Ferguson-Miller (Michigan State University)
7:55 pm - 8:25 pm Robert Gennis (University of Illinois at Urbana)
"The Super Family of Heme-Copper Oxidoreductases"
8:25 pm - 8:35 pm Discussion
8:35 pm - 9:05 pm David Kramer (Michigan State University)
"The Proton Circuit of Photosynthesis"
9:05 pm - 9:15 pm Discussion
9:15 pm - 9:30 pm Open Discussion: Shelagh Ferguson-Miller (Michigan State University)
MONDAY
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmChannels and Transporters I
9:00 am - 9:15 am Session Chair: Tom DeCoursey (Rush University, Chicago)
9:15 am - 9:40 am William Degrado (University of California at San Francisco)
9:40 am - 9:50 am Discussion
9:50 am - 10:15 am Susan Smith (Emory University)
"Aspartate at the Selectivity Filter: On the Road to the Electric Proton Channel Acid Test"
10:15 am - 10:25 am Discussion
10:25 am - 10:55 am Coffee Break
10:55 am - 11:20 am Yasushi Okamura (Osaka University)
"Gating Mechanisms of Voltage-Gated Proton Channels"
11:20 am - 11:30 am Discussion
11:30 am - 11:55 am Claudio Grosman (University of Illinois at Urbana-Champaign)
"The Unanticipated Complexity of the Ring of Glutamates in the Charge-Selectivity Filter of the Nicotinic Acetylcholine Receptor"
11:55 am - 12:05 pm Discussion
12:05 pm - 12:30 pm Open Discussion: Mei Hong (Iowa State University) and Joachim Heberle (Freie Universitat Berlin)
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmEmerging Methodology
7:30 pm - 7:45 pm Session Chair: Colin Wraight (University of Illinois at Urbana-Champaign)
7:45 pm - 8:10 pm Steve Sligar (University of Illinois at Urbana-Champaign)
"Proton Control of Mixed Function Oxidase Activity"
8:10 pm - 8:20 pm Discussion
8:20 pm - 8:45 pm Mark Chance (Case Western Reserve University)
"Structural Mass Spectrometry of Membrane Proteins and Water Dynamics"
8:45 pm - 8:55 pm Discussion
8:55 pm - 9:20 pm Tim Cross (Florida State University)
"Managing the Charge Distribution in the Histidine Tetrad Responsible for Transport in the M2 Proton Channel"
9:20 pm - 9:30 pm Discussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmChannels and Transporters II
9:00 am - 9:15 am Session Chair: Bob Stroud (University of California at San Francisco)
9:15 am - 9:40 am David Stokes (Skirball Institute - New York University)
"ATP-dependent Cu transport by CopA"
9:40 am - 9:50 am Discussion
9:50 am - 10:15 am Lucy Forrest (Max-Planck Institut für Biophysik)
"The elegant role of structural symmetry in transport across membranes"
10:15 am - 10:25 am Discussion
10:25 am - 10:55 am Coffee Break
10:55 am - 11:20 am Emad Tajkhorshid (University of Illinois at Urbana-Champaign)
"Characterizing Functional Motions and Chemomechanical Coupling Mechanisms in Membrane Transporters"
11:20 am - 11:30 am Discussion
11:30 am - 11:55 am Christian Bamann (Max-Planck Institut für Biophysik)
"Channelrhodopsin 2: Molecular Properties and Applications"
11:55 am - 12:05 pm Discussion
12:05 pm - 12:30 pm Open Discussion: Joachim Heberle (Freie Universitat Berlin) and Mei Hong (Iowa State University)
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmProton Transfer
7:30 pm - 7:45 pm Session Chair: Bertrand García-Moreno E. (Johns Hopkins University)
Discussion Leader: Alexei Stuchebrukhov (University of California at Davis)
7:45 pm - 8:10 pm Steve Schwartz (Albert Einstein College of Medicine)
"Hydrogen Transfer in Enzymes - Not all the Same!"
8:10 pm - 8:20 pm Discussion
8:20 pm - 8:45 pm Arieh Warshel (University of Southern California)
"Coarse Grained Modeling of Proton Translocation, Ion Current and Voltage Effects in Membrane proteins"
8:45 pm - 8:55 pm Discussion
8:55 pm - 9:20 pm Leif Hammarström (Uppsala University)
"Mechanisms of Proton-Coupled Electron Transfer in Amino Acid Model Complexes"
9:20 pm - 9:30 pm Discussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmLipid and Lipid Protein Interactions
9:00 am - 9:15 am Session Chair: Alexey Ladokhin (University of Kansas Medical Center)
9:15 am - 9:40 am Toby Allen (University of California at Davis)
"Understanding charged protein-lipid interactions and unassisted membrane ion transport"
9:40 am - 9:50 am Discussion
9:50 am - 10:15 am Karen Fleming (Johns Hopkins University)
"A Novel Side Chain Hydrophobicity Scale Derived from Transmembrane Protein Folding into Phospholipid Bilayers"
10:15 am - 10:25 am Discussion
10:25 am - 10:55 am Coffee Break
10:55 am - 11:20 am James U. Bowie (University of California at Los Angeles)
"Energetics of Membrane Protein Folding"
11:20 am - 11:30 am Discussion
11:30 am - 11:55 am Donald Engelman (Yale University)
"Transmembrane helix insertion driven by protonation: mechanism and uses"
11:55 am - 12:05 pm Discussion
12:05 pm - 12:30 pm Open Discussion: Alexey Ladokhin (University of Kansas Medical Center)
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
7:30 pm - 9:30 pmATPase
7:30 pm - 7:45 pm Session Chair: Wolfgang Junge (Universität Osnabrück)
7:45 pm - 8:10 pm José Faraldo-Gómez (Max-Planck Institut für Biophysik)
"Multi-scale theoretical studies of the mechanism and organization of ATP synthases"
8:10 pm - 8:20 pm Discussion
8:20 pm - 8:45 pm Wayne Frasch (Arizona State University)
"Functional Consequences of Releasing the Fo-Leash on the FoF1 ATP synthase"
8:45 pm - 8:55 pm Discussion
8:55 pm - 9:20 pm Tom Meier (Max-Planck Institut für Biophysik)
"Coupling of Na+/H+ Transfer to the Rotary Mechanism of ATP Synthase"
9:20 pm - 9:30 pm Discussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmElectron and Proton Transfer Reactions
9:00 am - 9:15 am Session Chair: Pia Ädelroth (Stockholm University)
9:15 am - 9:40 am Leo Sazanov (Medical Research Council, UK)
"Structure and Mechanism of Respiratory Complex I"
9:40 am - 9:50 am Discussion
9:50 am - 10:15 am Qiang Cui (University of Wisconsin)
"QM/MM analysis of proton pumping in Cytochrome c oxidase"
10:15 am - 10:25 am Discussion
10:25 am - 10:55 am Coffee Break
10:55 am - 11:20 am P. Leslie Dutton (University of Pennsylvania)
"The Freewheelin' Q-Cycle"
11:20 am - 11:30 am Discussion
11:30 am - 11:55 am Fabrice Rappaport (Institut de Biologie Physico-Chimique)
"Coupling Between Proton and Electron Transfer in the Oxidation of Water Driven by Photosystem II"
11:55 am - 12:05 pm Discussion
12:05 pm - 12:30 pm Open Discussion: Peter Brzezinski (Stockholm University)
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 8:30 pmKeynote Address
Session Chair: Terry A. Krulwich (Mount Sinai School of Medicine)
7:30 pm - 8:10 pm John Walker (Medical Research Council, UK)
"Proton:ATP ratios in mitochondria"
8:10 pm - 8:30 pm Discussion
8:30 pm - 9:30 pmRecognition of Junior Investigators
8:30 pm - 8:40 pm TBA (Short Talk Selected from Posters)
8:40 pm - 8:45 pm Discussion
8:45 pm - 8:55 pm TBA (Short Talk Selected from Posters)
8:55 pm - 9:00 pm Discussion
9:00 pm - 9:10 pm TBA (Short Talk Selected from Posters)
9:10 pm - 9:15 pm Discussion
9:15 pm - 9:25 pm TBA (Short Talk Selected from Posters)
9:25 pm - 9:30 pm Discussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture
© 2016 Gordon Research Conferences Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter