Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Sex Differences in Alcohol Research
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:05 pm
"Sex Differences in Alcohol-Motivated Behavior: Role of Stress, Circulating Gonadal Hormones, and Glutamate Systems"
4:05 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
"Maternal and Paternal Lineage Contributions to Transgenerational Effects of Prenatal Alcohol Exposure"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Molecular Signatures of Alcohol Abuse
7:30 pm - 7:45 pm
"CRISPR-Cas9 Editing of Hypocretin (Orexin) Receptor Genes in Cell Type-Specific Extended Amygdala Neurons Modulating Alcohol Drinking and Anxiety-Related Behavior "
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"d-GABAA Receptor Mediated Tonic Inhibition on Parvalbumin Interneurons Is Critical Target for Binge Drinking and Alcohol-Associated Anxiety"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"Selective Lesioning of Nuclear Factor-kB Activated Cells in the Nucleus Accumbens Shell Attenuates Alcohol Place Preference"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"The Role of LRRK2, a Parkinson's Disease-Related Protein, in Regulating Striatal Function and Alcohol Drinking in Mice"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Stress, Nicotine, and Drugs of Abuse Converge onto the GABAergic Circuitry of the VTA and Increase Ethanol Self-Administration"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Acute Ethanol Exposure Enhances Ubiquitination and Degradation of β-Arrestin in Rat Prefrontal Cortex and Neuroblastoma N2A Cells"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Brainwide Circuits Defining Drinking
9:00 am - 9:15 am
"Alcohol-Induced Neuroadaptation of IL-1 Signaling at GABAergic Synapses in the Mouse Prelimbic Cortex"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"The Role of Cortical Neuropeptides in Binge-Like Consumption of Ethanol"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"CeA Projections to PAG Mediate Alcohol Dependence-Induced Hyperalgesia in Rats"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"The Role of the Basolateral Amygdala-Nucleus Accumbens Circuitry in Alcohol Addiction Vulnerability"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Distinct Striatal Targets for Midbrain Dopamine Neurons that Support Alcohol-Seeking Elicited by Discrete and Contextual Environmental Cues"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
"Disentangling the Effects of Exogenous Ghrelin Administration in Relation to Alcohol Versus Food Reward Anticipation in Alcohol-Dependent Individuals: A Brain fMRI Study"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Grantsmanship
1:30 pm - 2:30 pm
Panel Discussion
NIH Fellowships and Early Career Development Grants
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes