Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Binge and Compulsive Drinking
3:45 pm - 3:55 pm
"The Role of the Anterior Insular Cortex in Modulating Binge-Like Alcohol Consumption"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"The Maladaptive Alcohol Self-Administration Task (MAST): A Novel Rodent Model of Alcohol Seeking and intake"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Dorsal Medial Prefrontal Cortex Neural Firing Correlates of Compulsive Drinking In Alcohol Preferring P Rats"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Genetic and Non-Neuronal Mechanisms of Ethanol Consumption
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 7:50 pm
"Iterative ATAC-seq (Assay for Transposase-accessible Chromatin) to Hone in Neurons Regulating Alcohol Responses"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:05 pm
"Spatial Transcriptomics and snRNA Sequencing Identify Spatially Resolved Overlapping Prefrontal Cortex Cell-Type Specific Mechanisms Between Alcohol Dependence and Immune Activation Mouse Models"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Role for the Poly r(C)-Binding Protein 1 (PCBP1) in Altered RNA Splicing in the Hippocampus of Rats During Withdrawal From Chronic Ethanol Exposure and Human Subjects with AUD"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:35 pm
"Predator Odor (TMT) Exposure Potentiates Alcohol Interoceptive Sensitivity and Alters Gene Expression in the Anterior Insular Cortex"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Baseline Inflammatory Biomarker Levels are Associated with Drinking Outcomes in a Randomized Controlled Trial of Ibudilast"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"Adolescent Binge Ethanol Exposure Results in Protracted Changes in Astrocyte Morphology, Function, and Astrocyte-Synaptic Colocalization That Disrupts Neuronal-Astrocyte Ca2+ Responsivity"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Reward Learning and Sex-Specific Effects of Alcohol Consumption
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:15 am
"BDNF Signaling in the Nucleus Accumbens Mediates Alcohol Reward"
9:15 am - 9:20 am
Discussion
9:20 am - 9:30 am
"Low Dose Ethanol Enhances Modulation of Ventral Hippocampus Activity During Motivated Behavior"
9:30 am - 9:35 am
Discussion
9:35 am - 9:45 am
"The Circuit Basis of Operant Self-Administration for Ethanol in Drosophila Melanogaster"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
"Alcohol and Vapourized Nicotine Co-Exposure During Adolescence Contribute Differentially to Sex-Specific Behavioural Effects in Adulthood"
10:00 am - 10:05 am
Discussion
10:05 am - 10:15 am
"Adolescent Voluntary Alcohol Drinking Impairs Response Inhibition and Alters Cortical-Striatal Dynamics in Male and Female Rats"
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Sex-Specific Effects of Alcohol on Inflammatory Pain and Corticolimbic Endocannabinoid Signaling"
10:30 am - 10:35 am
Discussion
10:35 am - 10:45 am
"Sex-Specific Regulation of Binge Alcohol Drinking and Associated Negative Affective Behaviors by Serotonin 5HT2c Receptors"
10:45 am - 10:50 am
Discussion
10:50 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Enhancing DEI in the Alcohol Community
1:30 pm - 2:30 pm
Panel Discussion
Issues of Diversity and Inclusion in the Alcohol Field and Biomedical Sciences
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
