Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Human Factors and Behavior Drive the Interaction Between Patient and Device
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:05 pm
"The Unmeasured Psychological Impact of Durable MCS on the Patient and Family"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"Enhancing the Patient Experience with Durable MCS at Home and With Providers"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"Optimizing Healthcare Team Decision-making for Equity"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Caregiver Availability and Eligibility for MCS Therapy"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Contemporary Practices in Selection of Patients for MCS Leaves Undertreated Populations
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Engineering MCS Devices to Address Different Heart Sizes and Heart Anatomy"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
"Mechanical Circulatory Support Device for Heart Failure with Preserved Ejection Fraction (HFpEF) - Learnings from Concept to Startup"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Device Usability Engineering Considerations to Advance MCS in Challenging Patient Populations"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:10 am
"Leveraging Unpublished Insights from the ACTION Network to Advance Clinical Decision-Making in Pediatric Mechanical Circulatory Support"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"The Current and ‘Relentless’ Future Need for Durable VAD in ACHD Patients: An Exploration of Numbers and Unique Physiologies"
11:35 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Design Features of a MCS Device Utilized for a Bridge to Recovery Strategy That Will Enhance the Propensity for Recovery and lead to Greater Adoption of the Strategy"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hour™ is open to all conference participants.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Computer Learning and Simulation to Improve Patient Selection, Patient Management and Device Design and Development
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:20 pm
"Outcomes Following Durable MCS Therapies Are Improved by Prognostic Models Utilizing AI Algorithms"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
"Modeling the Use of Durable MCS to Promote Long Term Survival and Optimal Heart Donor Organ Utilization"
6:45 pm - 6:55 pm
Discussion
6:55 pm - 7:10 pm
"Innovative Approaches to Improve Hemocompatibility in MCS Devices"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:35 pm
"Machine Learning for Assisted Circulation: Haemodynamics and Device Design"
7:35 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
New Technology Blurs the Line Between the Designation of Short Term and Long Term MCS Strategies
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Renal Perfusion Enhancement for Decongestion in Decompensated Heart Failure"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
"Design Hurdles And Features Of A Counter-Pulsation MCS Device Suitable For Patient Ambulation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Impella Outcomes in Children"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:10 am
"Potentials and Obstacles of Patient Monitoring and Physiologic Control"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Dynamic Modulation of Device-Arterial Coupling to Determine Cardiac Output and Vascular Resistance"
11:35 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Dynamic Load Modulation Predicts Right Heart Tolerance to Left Ventricular Cardiovascular Assist"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Novel Concepts Applied to the Hemodynamic Evaluation and Treatment of Right Heart Failure
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:20 pm
"Advanced Hemodynamics, Right Ventricular Optimization and Hemodynamic Related Events in LVAD Recipients: The Next Frontier of Durable Support"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
"Rotary Blood Pump Features May Expand the Role of Total Artificial Heart Therapy"
6:45 pm - 6:55 pm
Discussion
6:55 pm - 7:10 pm
"Interactions of the Ventricular Septum During Left Ventricular Unloading"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:35 pm
"Distinguishing Right Heart Failure Phenotypes to Determine If, When and How Durable MCS Should be Applied"
7:35 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Recovery and Remission to Enhance the Utilization of MCS Therapy
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Recovery From Advanced HF: Candidate Selection, Durability and Magnitude of Opportunity"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
"Defining the Phenotype of Myocardial Recovery though Proteomics: Novel Biological Patterns"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:45 am
"Therapeutic Targeting of RUNX1 in Cardiac Recovery"
10:45 am - 10:55 am
Discussion
10:55 am - 11:10 am
"Novel Pump Designs Based Upon the Venturi Effect"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Recoupling or Recovery: Right Ventricular Function after LVAD with Persistent Pulmonary Hypertension"
11:35 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Innovative Surgical Techniques for Faster Post-operative Recovery"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Clinical and Pre-Clinical Evaluation of Short Term and Long Term MCS Devices Has Evolved
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:20 pm
"Industry Perspectives on Contemporary Clinical Trial Designs for MCS Devices for Acute and Long-Term Applications"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
"Using a Collaborative Network for Device Trials and Expanded Labeling in Pediatrics"
6:45 pm - 6:55 pm
Discussion
6:55 pm - 7:10 pm
"Advancing the Preclinical Hemocompatibility Evaluation of Rotodynamic Blood Pumps"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:35 pm
"The Molecular Basis for Cardiac Unloading in Acute Myocardial Infarction With and Without Cardiogenic Shock"
7:35 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Mechanical Circulatory Support Devices Impact Hemodynamics and Vascular Biology
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:20 am
"Hemodynamic determinants of kidney dysfunction in advanced heart failure: Implications for renal assist devices"
9:20 am - 9:30 am
Discussion
9:30 am - 9:45 am
"To Pulse or not to Pulse: That is the Question"
9:45 am - 9:55 am
Discussion
9:55 am - 10:10 am
"Arterial Afterload Hemodynamics in Veno-Arterial ECMO"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"Microvascular Alterations During Continuous Flow Mechanical Circulatory Support"
11:05 am - 11:15 am
Discussion
11:15 am - 11:30 am
"LES as Validation Benchmark for RANS Models in Blood Pumps and the Implication of Non-Rotatory Impeller Motion"
11:30 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Xenotransplantation, Allotransplantation, Cellular Regeneration, Medical Therapy: Can Durable MCS Stand Up to the Challenge"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Early Evaluation of Novel Device Designs
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:15 pm
"Optimization of Circulatory Support Algorithms for the TORVAD"
6:15 pm - 6:20 pm
Discussion
6:20 pm - 6:30 pm
"The BrioVAD Experience: Device Design, Clinical Trial Design, Enrollment, and Clinical Update"
6:30 pm - 6:35 pm
Discussion
6:35 pm - 6:45 pm
"CorWave LVAD - Pulsatile, Self-Adaptive Wave Membrane Technology"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:00 pm
"Mi-VAD: A Novel Intra-Vascular Cardiac Assist Device; Moving Away from the Apical Cannulation Paradigm"
7:00 pm - 7:05 pm
Discussion
7:05 pm - 7:25 pm
"Focusing and Prioritizing the Development of Durable MCS Device Technology."
7:25 pm - 7:35 pm
Discussion
7:35 pm - 7:55 pm
General Discussion
7:55 pm - 8:00 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure