Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Lipids and Inflammation
7:40 pm - 8:05 pm
"Novel Insights Relating Inflammation to Aging and Longevity"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Clonal Hematopoiesis, Inflammasomes and Atherosclerosis"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Molecular Signatures of Atherosclerosis Regression"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cellular Plasticity and Clonality in Atherosclerosis
9:00 am - 9:20 am
"Clonal Hematopoiesis in Atherosclerosis: Expanding Clones, Expanding Risk"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Vascular Smooth Muscle Cell Heterogeneity in Disease"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Fibroblast Identity, Origin, Fate and Function in Ageing and Atherosclerosis"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Dissecting Atherosclerotic Calcification: Unveiling the Role of Extracellular Vesicles and Microcalcification in Plaque Rupture"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Dissecting Human Atherosclerosis with Multi-Omics Approaches"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Dissecting Antigen-Specific T Cell-Responses in Atherosclerosis"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hourâ„¢ is open to all conference participants.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Atherosclerosis and Immunology: Translational Progress
6:00 pm - 6:20 pm
"Targeting Adaptive Immunity in Patients with Atherosclerotic Cardiovascular Disease"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Genetic Regulation of Innate-like B Cells in Atherosclerosis"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Uncovering Atherosclerotic CVD by PET Imaging"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Deciphering Innate and Adaptive Immune Cell Responses in AMI Patients with Plaque Erosion and Rupture"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Genomics, Genetics, and Bioinformatics in Atherosclerosis
9:00 am - 9:20 am
"Clonal Hematopoiesis and Coronary Artery Disease"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Decoding Vascular Disease using Human Genetics and Single-Cell Omics"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Using Genomics to Unravel the Cardiovascular Component of Dementia"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Exploring the Genetic Basis of Atherosclerosis with Single-Cell, Spatial, and Functional Genomics"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Translating Genetic Information into Clinical Decision Making"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Decoding Atherosclerosis: Macrophages and Their Subsets as Predictors of Cardiovascular Risk"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:20 pm
"Immune-Checkpoint Inhibitors: Insights into Cardiovascular Biology"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Cancer Therapy Cardiotoxicity Due to Endothelial Damage, Vascular Inflammation and Plaque Rupture"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Defining the Underpinnings of Immune Responses to Checkpoint Myocarditis across Heart, Blood and Tumor"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Reverse Cardio-Oncology: Mechanisms Driving Tumor Growth After Myocardial Infarction"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Inflammation, Immunity and Atherosclerosis: Basic Mechanisms
9:00 am - 9:20 am
"The Spatial Odyssey of the Human Atherosclerotic Plaque"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Controlling Endothelial and Immune Cell Homeostasis in Atherosclerosis"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Targeting Trem2+ Foam Cells in Atherosclerosis"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Loss of Tolerance to ApoB in Atherosclerosis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Sex Differences in the Immune Response Impact Cardiovascular Disease"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Emerging Mosquito-Borne Viruses as Environmental Stressors to Cardiovascular Health"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
The Neuro-Vascular Axis and the Role of Environmental Stressors in Atherogenesis
6:00 pm - 6:20 pm
"Lifestyle and Heart-Brain Communication"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Neuro-Vascular-Immune Interactions in Aging"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Cardiogenic Regulation of Sleep in Cardiovascular Disease"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"From Pollution to Prevention: The Environmental Roots of Cardiovascular Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Lipid Metabolism and its Translation
9:00 am - 9:20 am
"Cholesterol Efflux: From Pathophysiology to Therapeutic Advances"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Metabolism and Atherogenicity of Triglyceride-Rich Lipoproteins"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"RAGE/DIAPH1: Roles in Atherosclerosis Through Modulation of Mitochondrial Function and Actin Cytoskeleton Dynamics"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Macrophage Phospholipid Metabolism in Vascular Inflammation and Atherosclerosis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"The Paradox of LIPA in Atherosclerosis"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Microbial Metabolites in the Progression of Atherosclerosis"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Keynote Session: Smart Drugs, Gene Therapy and Biomarkers
6:00 pm - 6:30 pm
"Overcoming Obesity: The Discovery of Multi Receptor Drugs"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"Discovery and Pharmacological Targeting of Pathways that Contribute to Residual Cardiovascular Risk"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"Towards Developing a One-Time Gene Editing Treatment for a Lifetime of Cholesterol-Lowering Benefit"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure