Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Cell Envelope Macromolecular Machines
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:15 pm
"Machines Making Membranes"
8:15 pm - 8:25 pm
Discussion
8:25 pm - 8:55 pm
"Folding OMPs into The Outer Membrane: How Do Bacteria Do It?"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
"Phospholipid Transport To The Bacterial Outer Membrane Through An Envelope-Spanning Bridge"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Division and Morphogenesis
9:00 am - 9:20 am
"Staphylococcus Aureus Cell Division: In Sickness and in Health"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Cell Division and Morphogenesis of Streptococcus pneumoniae "
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Protein Coopted From A Phage Restriction System Dictates Orthogonal Cell Division Plane Selection in Staphylococcus aureus "
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"A Novel Role for Carboxypeptidases in Peptidoglycan Endopeptidase Regulation"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Coordination of Cell Division and Initiation of Polar Flagellation in Campylobacter jejuni "
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Cryo-EM Structure of the MreCD Complex Reveals a Multifaceted Interface that Controls MreC Conformation"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Role of Membrane Fluidity on Cell Wall Elongation Machineries in Bacillus subtilis "
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Decoding the Role of Lytic Transglycosylase Protein Complexes in Peptidoglycan Degradation Machine"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Sensing Through The Cell Envelope
7:30 pm - 7:50 pm
"Regulatory Mechanisms Controlling Biofilm Formation in Vibrio cholerae "
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Lifecycle Of a Predatory Bacterium Feeding from the Prey Cell Surface"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Acinetobacter Baumannii Utilizes a TPR-Domain Protein as A Cell Division Amidase Activator"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Stress of Building an Outer Membrane: The Long and the Short of It"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Cyclic-di-AMP Controls Cellular Turgor in Response to Defects in The Cell Wall"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Coordinating and Balancing Cell Envelope Biogenesis
9:00 am - 9:20 am
"Dissecting The Link Between Membrane and Cell Wall Biosynthesis in Bacillus subtilis "
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"A Periplasmic Proteolytic System Coordinates the Cell Envelope Expansion in E. coli "
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Revealing The Interrelations Between LPS and OMPs Dynamics in Live Bacteria"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Stress Resistance of The Brucella Abortus Envelope Depends on A Mla-Pqi Chimeric System"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Interplays Between Envelope Permeability and Phospholipid Homeostasis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Regulatory Mechanisms of Lipopolysaccharide Synthesis in Escherichia Coli "
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Teichoic Acids as Master Coordinators of Growth in Bacillus Subtilis "
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"An Octameric PqiC Toroid Stabilizes the Outer-Membrane Interaction of the PqiABC Transport System"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Modification and Evolution of the Bacterial Envelope
7:30 pm - 8:00 pm
"One or Two Membranes? Illuminating The Evolution of the Cell Envelope across The Tree of Bacteria"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"Cell Envelope Diversity of Early-Branching Phyla"
8:45 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Structural and Mechanistic Insights into Lipid A Modification Systems in Gram-Negative Bacteria"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"A Novel Mechanism of Membrane Defense in Gram-Negative Bacteria Against Environmental Stress"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Maintenance of the Cell Envelope
9:00 am - 9:20 am
"Outer Membrane Lipid Homeostasis in Gram-Negative Bacteria"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Nanodomain Formation in The Outer Membrane"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"The Soluble Periplasmic Protease BepA is Tightly Anchored to The Outer Membrane via a Single Conformational Change"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Molecular Interactions between Outer Membrane Lipid Asymmetry and Peptidoglycan Integrity Maintenance in Acinetobacter Baumannii "
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Molecular Mechanisms of Cell Envelope Biogenesis and Remodeling in a Gram Positive Pathogen"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Molecular Safety Mechanism That Prevents Aberrant Inner Membrane-Peptidoglycan Linkages Mediated by Lpp in E. coli "
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Outer Membrane Destabilization through Reduction in Protein Density"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Helical Cell Shape Associated Cell Wall Features: Chicken or Egg?"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Targeting the Cell Envelope with Antimicrobials
7:30 pm - 7:50 pm
"Multidrug Efflux in The Multiverse of Antibiotic Resistance"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Host Directed Therapies: Synergy in Unexpected Places"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Protein Folding Elements Enable Genetic Innovation in Antibiotic Resistance Genes"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Zosurabalpin, a New Antibiotic Targeting the Lipopolysaccharide Transporter"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"A Novel Antibacterial Targets LOS Transport in Drug-Resistant Acinetobacter Baumannii "
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Interplay Between the Bacterial Envelope and Communities
9:00 am - 9:20 am
"Exploring The Structural Diversity & Functional Versatility of the Type V Secretion System"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Spatial and Temporal Regulation of Type 6 Secretion System Dynamics"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Insight into Dynamics and Gating Properties of T2SS Secretins"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"The Fate of Survivors: The Impact of Released Phage Peptides on Neighboring Host Bacteria"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Massively Parallel Barcode Sequencing Revealed The Interchangeability of Capsule Transporters in Streptococcus pneumoniae "
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Spatial Propagation of Temperate Phages Within and Among Bacterial Biofilms"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Lipoprotein Processing and Localization in Bacteroides"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Fortifying the Cell Envelope in Bacillota (Firmicutes): Self-Assembling Proteins Create Paracrystalline Layers for Enhanced Stability in Vegetative Cells and Spores"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Envelope-Dependent Behaviors
7:30 pm - 7:50 pm
"Bacterial Contractile Injection Systems: Structure, Function, Evolution and Re-Engineering"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Cell Envelope-Dependent Regulation of Photo Sensing by a Small Periplasmic Protein"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Regulation and Structural Analysis of Membrane-Derived Vesicles And Tubes in Francisella"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"It's All in The Membrane: Regulation and Mechanisms of Horizontal Gene Transfer by Natural Transformation in Vibrio cholerae "
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Remodeling of Bacterial Surface during V. cholerae Biofilm Development"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure