Saturday |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Session: Regulation of Barrier Maintenance and Heterogeneity in the CNS |
| Discussion Leaders: Damir Janigro (Flocel Inc., USA) and Brandon Kim (San Diego State University, USA) |
3:45 pm - 4:15 pm | Stefan Liebner (University of Frankfurt, Germany) "Regulation of Barrier Maintenance and Heterogeneity in the CNS" |
4:15 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CNS Barriers in Health and Disease |
| Discussion Leaders: Aric Logsdon (West Virginia University, USA) and Steffen Storck (Johannes Gutenberg-University of Mainz, Germany) |
7:30 pm - 7:50 pm | Regina Faubel (Max-Planck Insitute for Biophysical Chemistry, Germany) "Ependymal Cilia Generate a Logistic Network" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Aaron Dadas (Flocel Inc., USA) "Evidence for or Against Glymphatic Clearance of Phosphorylated Tau in Human Brain" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Marijke De Bock (Ghent University, Belgium) "Connexin and Calcium Signaling in Glial and Endothelial Cells Are Implicated in Inflammation-Induced Blood-Brain Barrier Permeability Changes In Vivo" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Matthew Simon (Oregon Health and Science University, USA) "Age-Linked Regulation of Perivascular Localization of the Astrocytic Water Channel Aquaporin-4 (AQP4)" |
9:20 pm - 9:30 pm | Discussion |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Delivery to the CNS |
| Discussion Leaders: Irena Loryan (Uppsala University, Sweden) and Jeff Lochhead (University of Wisconsin-Madison, USA) |
9:00 am - 9:20 am | Aurore Lebrun (Thomas Jefferson University, USA) "Non Pathological Delivery of Immune Effectors Across the Blood-Brain Barrier" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Piotr Siupka (Aarhus University, Denmark) "Receptors Trafficking in Brain Endothelial Cells, and Its Implication for Receptor Mediated Transcytosis and Drug Delivery to the Brain" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Michelle Pizzo (University of Wisconsin-Madison, USA) "Investigating the Whole Brain Distribution of Intrathecally Applied Antibodies and Antibody Fragments Using Ex Vivo Fluorescence Microscopy and In Vivo Magnetic Resonance Imaging" |
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Dongfen Yuan (University of North Carolina at Chapel Hill, USA) "Synthesis, Characterization and Intranasal PK Analysis of N-Terminally Modified Pluronic Leptin for Treatment of Obesity" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship Component: Career Panel |
| Discussion Leader: Robert Thorne (University of Wisconsin-Madison, USA) |
1:30 pm - 2:30 pm | Panel Discussion |
| "Scientific Career Paths" |
|
- Bjoern Bauer (University of Kentucky, USA)
- Robert Bell (Pfizer, USA)
- Elizabeth De Lange (Leiden University, The Netherlands)
- Britta Engelhardt (University of Bern, Switzerland)
|
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |