Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Cell Types of the Basal Ganglia
7:40 pm - 8:00 pm
"Cell Type Organization in the Basal Ganglia"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Morphological Reevaluation of Basal Ganglia Network"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Cell Type-Specific Intracellular Signaling in Response to Multiple Neuromodulators in the Striatum"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Striatal Cholinergic Interneuron Membrane Voltage Tracks Locomotor Rhythms in Mice"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Exploring Neural Dynamics in Reward Learning and Motivated Behavior"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Shaping Behavioral Choice with Parallel Dopamine Systems"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Imaging Dopamine Signaling Aberrations in Huntington's Disease with Near-Infrared Nanosensors"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"An Optical Nanosensor for Visualizing Dopamine Release at the Resolution of a Single Bouton"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Action Prediction Error: A Value-Free Dopaminergic Teaching Signal that Drives Stable Learning"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Precise Spatiotemporal Encoding of Striatal Dopamine Signals"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Gating of Opioid Withdrawal Aversion by Tshz1 Neurons in the Nucleus Accumbens"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Inputs and Outputs of the Basal Ganglia
7:30 pm - 7:50 pm
"Diverse Basal Ganglia Output Circuits Mediate Different Behaviors"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Regulation of Dopamine Release in the Nigrostriatal Pathway"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Motor and Non-Motor Functions of the GPe"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Striatal Circuit Contributions to Habit"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Complex Coding of Simple Movements in the Output of the Basal Ganglia"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Licensing Actions at the Intersection Between Basal Ganglia and Brainstem"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Basal Ganglia Mechanisms that Drive Birdsong Learning"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Movement-Related Increases in Subthalamic Nucleus Activity Optimize Locomotion"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Aberrant Striatal Activity and Top-Down Cortico-Striatal Synaptic Inputs in a Rodent Model of Impulse Control Disorder in Parkinson's Disease"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Thalamic Interaction of Basal Ganglia and Cerebellar Circuits During Motor Learning"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Mechanisms of Substance P Release from Striatal Direct Pathway Neurons"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Neural Circuits Involved in Non-Motor Symptoms of Parkinson`s Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Network Determinants of Disability in Parkinson’s Disease"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Corticostriatal Communication During Learning and Recovery of Reach to Grasp Actions"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Use of Motor Network Oscillatory Activity to Drive Closed Loop Neurostimulation"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Basal Ganglia and Decision-Making
9:00 am - 9:20 am
"Mechanisms of Rapid, Value-Dependent Updating Dopamine Signaling"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Cost and Benefit in the Dorsomedial Striatum"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Striatal Substrates Supporting Flexibility of Goal-Directed Action"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"The Role of Striatal Neurovascular Coupling in Auditory Learning"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Amygdala-Striatal Regulation of Punished Decision-Making"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Neural Mechanisms Underlying Planning and Movement"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Computation in the Basal Ganglia
7:30 pm - 7:40 pm
"Sensory Information Decreases Across the Basal Ganglia Axis While Behaviorally Relevant Information is Retained"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Goal-Directed Decision Making in Parkinson's Disease: Dopamine and Intracranial Recordings from Human Fronto-Basal Ganglia Circuits"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"How the Ventral Striatum Organizes Goal-Driven Behavior: A Systems-Neuroscience Computational Model"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"How the Basal Ganglia Influence Actions and Mazimize Reward Rate"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Distinct Basal Ganglia Decision Dynamics Under Conflict and Uncertainty"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Stress, Addiction and Mental Illness
9:00 am - 9:20 am
"Role of the Striatal Direct Pathway in Alcohol Drinking"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Striatal Alterations Drive Repetitive, Inflexible Behaviors in Mice with Autism-Related Mutations"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"A Cholinergic Brainstem Input to Nucleus Accumbens Neurons Determines Cocaine Place Preference"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Why Do Lateral Habenula-Projecting Neurons Co-Release Glutamate and GABA?"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"CRF Release from a Distinct Population of Accumbal Neurons Constrains Outcome-Action Acquisition"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Nigrostriatal Circuit Dysfunction in Neuropsychiatric Disease"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Loss of Cntnap2 Alters Striatal Neuron Excitability and Drives Repetitive, Inflexible Behaviors in Mice"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Dopamine Neuron Activity Produces Spatially Organized Decision Correlates Across Corticostriatal Networks"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Learning, Motivation and Goal-Directed Behavior
7:30 pm - 7:50 pm
"Cell Type Specific Auditory Responses in the Tail of the Striatum"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Dissociable Control of Motivation and Reinforcement by Distinct Ventral Striatal Dopamine Receptors"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"D1 and D2 Medium Spiny Neurons in the Nucleus Accumbens Core Have Distinct and Valence-Independent Roles in Learning"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Dynamic Neuropeptide Modulation Shapes Goal-Directed Behavior"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure