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Basal Ganglia (GRS)

Gordon Research Seminar

Illuminating Mechanisms of Basal Ganglia Function in Health and Disease

March 23 - 24, 2024

Chairs

and

Four Points Sheraton / Holiday Inn Express

1050 Schooner Drive

Ventura, California, United States

Venue and Travel Information

Conference Description

The Basal Ganglia GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

The Gordon Research Seminar on the Basal Ganglia offers graduate students, post-doctoral fellows, and other junior scientists a unique opportunity to share unpublished advancements and discuss emerging ideas within the field. The seminar will aim to inspire new insights into basal ganglia function and pathology by fostering connections across developmental, molecular, cellular, systems, computational, and theoretical approaches. It will also strive to provide a welcoming environment for researchers to celebrate shared scientific pursuit. Lastly, this seminar will include a career development session in which panelists discuss the evolving future of science as a profession and institution.

Related Meeting

This GRS will be held in conjunction with the "Basal Ganglia" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm	Basal Ganglia and Beyond: Downstream Structures Discussion Leader:
3:45 pm - 3:55 pm	"Corticonigral Projection Contributes to Auditory Threat Memories Through Recruitment of Dopaminergic Neurons in the substantia nigra pars lateralis"
3:55 pm - 4:00 pm	Discussion
4:00 pm - 4:10 pm	"Why Do Lateral Habenula-Projecting Neurons Co-Release Glutamate and GABA?"
4:10 pm - 4:15 pm	Discussion
4:15 pm - 4:25 pm	"Basal Ganglia Inhibition of the Rostral and Caudal Pedunculopontine Nucleus"
4:25 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Disorders of the Basal Ganglia Discussion Leader:
7:30 pm - 7:45 pm	"Goal-Directed Cognition in Parkinson's Disease: Dopamine and Electrophysiology in Human Fronto-Basal Ganglia Circuits"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	"Unraveling Extrapyramidal Symptoms with a Cell Type-Specific Dopamine Antagonist"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Gating of Opioid Withdrawal Aversion by Tshz1 Neurons in the Nucleus Accumbens"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Cholinergic Interneurons in the Nucleus Accumbens Mediate the Rewarding Properties of Opioid Drugs"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"Aberrant Striatal Activity and Top-Down Cortico-Striatal Synaptic Inputs in a Rodent Model of Impulse Control Disorder in Parkinson's Disease"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Loss of Cntnap2 Alters Striatal Neuron Excitability and Drives Repetitive, Inflexible Behaviors in Mice"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Basal Ganglia Circuits, Signaling, and Cell Types Discussion Leader:
9:00 am - 9:15 am	"Precise Spatiotemporal Encoding of Striatal Dopamine Signals"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"Tuning Dopamine Receptor Surface Expression with Genetically Expressed Nanobodies"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"The Dorsal Striatum Directs Exploratory Strategies Underlying Reinforcement Learning in Multi-Choice Environments"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"A Thalamo-Striatal Pathway Supports the Execution of Skilled Action Sequences"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"Investigating the Role of GABAergic Interneurons in the Dorsomedial Striatum in Goal-Directed Behavior"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	"Dopamine Dynamics Drive Birdsong Learning"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Advancing Scientific Excellence: The Role of Inclusive Leadership Discussion Leader:
1:30 pm - 2:30 pm	Panel Discussion Advancing Scientific Excellence: The Role of Inclusive Leadership
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Research reported in this publication was supported by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health under Award Number R13NS135891. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Basal Ganglia

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