Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Concepts At the Biointerface and Translational Biointerfaces
Discussion Leader: Matthew Paszek (Cornell University, United States)
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:30 pm
Viola Vogel (ETH Zurich, Switzerland)
"Mechanobiology of Healing"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
Jinwoo Cheon (IBS Center for Nanomedicine and Yonsei University, South Korea)
"Designer Nanomachines for Mechano-Biological Targets of Neuroscience and Beyond"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
DNA Nano-Structures at Biointerfaces
Discussion Leader: Simone Schuerle (ETH Zürich, Switzerland)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
Hanadi Sleiman (McGill University, Canada)
"DNA Nanostructures at Interfaces: Design and Biological Properties"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
Kerstin Göpfrich (Heidelberg University, Germany)
"Engineering a Synthetic Model Cell"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
Amelie Heuer-Jungemann (Max Planck Institute of Biochemistry, Germany)
"DNA Origami: A Platform for Studying Protein Properties, Functions and Interactions"
11:00 am - 11:10 am
Discussion
11:10 am - 11:30 am
Maartje Bastings (École Polytechnique Fédérale de Lausanne, Switzerland)
"How Rigid are Biointerfaces? Balancing Geometry and Flexibility in Nanomaterials for (Super )-Selectivity"
11:30 am - 11:40 am
Discussion
11:40 am - 11:55 am
Bruno Silva (Empa - Swiss Federal Laboratories for Materials Science and Technology, Switzerland)
"From Methodology to Insight: Unraveling the Assembly of Hybrid Core-Shell Bio-Inspired Polymer-Lipid Nanoparticles"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Carmen M. Dominguez (Karlsruhe Institute of Technology, Germany)
"Exploring Receptor Clustering Effects on Cellular Behaviour using DNA Origami Nanostructures"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Lanry Yung (National University of Singapore, Singapore)
"Protein-To-DNA Converter with High Signal Gain"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Kerstin Göpfrich (Heidelberg University, Germany)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Techniques for the Characterization of Biointerfaces
Discussion Leader: Sierin Lim (Nanyang Technological University, Singapore)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:30 pm
E. Ada Cavalcanti-Adam (University of Bayreuth, Germany)
"Deciphering the Mechanical Regulation of Endocytosis at the Interfaces"
6:30 pm - 6:35 pm
Discussion
6:35 pm - 6:55 pm
Pere Roca-Cusachs (Institute for Bioengineering of Catalonia, Spain)
"Understanding and Manipulating Nuclear Mechanotransduction"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
Simon Niederkofler (Chalmers University of Technology, Sweden)
"Biophysical Mechanisms of Lipid Nanoparticle-Mediated RNA Delivery: Interfacial interactions of Lipid Nanoparticles with Supported Lipid Bilayers"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Luona Zhang (Emory University, United States)
"Turbo-Charged DNA Motors with Optimized Sequence Enable Single-Molecule Nucleic Acid Sensing"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Yuru Hu (Wuhan University, China)
"DNA-Based ForceChrono Probes for Deciphering Single-Molecule Force Dynamics in Living Cells"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Nanorobotic and Molecular Robotics at Interfaces
Discussion Leader: Erik Winfree (Caltech, United States)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
Jwa-Min Nam (Seoul National University, South Korea)
"Mechanically Interlocked Plasmonic Nanomachines"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
Stephen Mann (University of Bristol, United Kingdom)
"Programmable Agency in Synthetic Protocells and Prototissues"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
Simone Schuerle (ETH Zürich, Switzerland)
"Engineering and Controlling Magnetic Microrobots for Tissue Probing and Enhanced Intra-and Transvascular Transport"
11:00 am - 11:10 am
Discussion
11:10 am - 11:25 am
Berna Özkale Edelmann (Technical University of Munich , Germany)
"Tissue Assembly and Regulation of Cell Behavior in 3D using a Microrobotic Approach"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
Karin Jacobs (Saarland University, Germany)
"Heterogeneous Adhesion Capability of S. Aureus Cell Surface: Is it a Model also for Artificial Cells?"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Juan Martinez (University of Leeds, United Kingdom)
"Composition-Dependent Tuneability of the Cell Interactions of Hybrid Vesicles"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Sarah Speed (Institut für Polymerforschung, Germany)
"Programmable Binding and Separation of Biomolecules by Reversibly Crosslinked DNA-Functionalized Polymers"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Data Driven Biointerfaces Discoveries
Discussion Leader: Morgan Alexander (University of Nottingham, United Kingdom)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
Jan de Boer (Eindhoven University of Technology, The Netherlands)
"Pixels and Nucleotides: the Building Blocks of Predictive Models on Cell-Biomaterial Interaction"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
Lulu Qian (California Institute of Technology, United States)
"Sustainable Computation in Heat Powered DNA Logic Circuits and Neural Networks"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Gaurav Arya (Duke University, United States)
"Modeling DNA Origami Folding and Higher-Order Assembly"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Wenting Zhao (Nanyang Technological University, Singapore)
"The Impact of Nanoscale Membrane Deformations at the Biointerface"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Udi Sarig (Ariel University, Israel)
"Instantly Interfacing Microfluidic Bio-Chips with Bioprinted Mucosa-Mimicking Tissue Models"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Immune Receptors at Interfaces
Discussion Leader: Jay Groves (UC Berkeley, United States)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
Morgan Huse (Memorial Sloan Kettering Cancer Center, United States)
"Force Exertion and Mechanosensing at Immune Cell-Cell Interfaces"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
Omer Dushek (University of Oxford, United Kingdom)
"Matched Receptor/Ligand Sizes Determines Signalling at Immune Cell Interfaces"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
Li Tang (EPFL, Switzerland)
"Multidimensional Immunoengineering Approaches to Enhanced Cancer Immunotherapy"
11:00 am - 11:10 am
Discussion
11:10 am - 11:25 am
Milad Radiom (ETH-Zürich, Switzerland)
"Secretory IgA Interactions Direct Protection Against Salmonella Typhimurium Infection in the Gut: Effect of Interaction Parameters and Gut Motility"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
Yan Yu (Indiana University, United States)
"The Hierarchical Organization Driving Pathogen-Host Interactions"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Giovanni Bovone (Harvard SEAS, United States)
"Aging-Induced Changes in the Potency of Immune Response Following Mesoporous Silica Rod-Based Cancer Vaccination"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Caitlin Howell (University of Maine, United States)
"Sensing and Control of Living Systems at Interfaces through Buried Vascular Networks"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Translational Biointerfaces Towards Diagnostics
Discussion Leader: Ashutosh Chilkoti (Duke University, United States)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:30 pm
Suzie Pun (University of Washington, United States)
"Aptamers in Biomedical Applications"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:00 pm
Fredrik Hook (Chalmers University of Technology, Sweden)
"Extracellular Vesicle and Lipid Nanoparticle Fingerprinting and Cell-Membrane-Interaction Analysis Using Label-Free Surface Sensitive Optical Microscopy"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Jurriaan Huskens (University of Twente, The Netherlands)
"Multivalent Interactions at Interfaces in the Detection of DNA and Viruses"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:45 pm
Wade Zeno (University of Southern California, United States)
"Functional Disorder at Biological Membranes"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Mechanobiology at the Cell Surface
Discussion Leader: Joachim Rädler (LMU, Germany)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
Taekjip Ha (Boston Children's Hospital, United States)
"Mechanotransduction at Single Molecule Resolution"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
Aránzazu del Campo (INM - Leibniz Institute for New Materials, Germany)
"Engineered Living Therapeutic Materials"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 10:55 am
Minsuk Kwak (Yonsei University, South Korea)
"Nanoscale Approaches for Understanding and Modulation of Mechanical Receptor Signaling for Mechanobiology and Therapeutics"
10:55 am - 11:00 am
Discussion
11:00 am - 11:15 am
Elisha Krieg (Leibniz-Institut für Polymerforschung Dresden e.V., Germany)
"DNA Nanotechnology Makes Synthetic Matter Talk to Cells"
11:15 am - 11:20 am
Discussion
11:20 am - 11:30 am
Selin Bulut (DWI - Leibniz Institute for Interactive Materials, Germany)
"Cellular Architects at Work: Cells Building Their Own Microgel Houses"
11:30 am - 11:35 am
Discussion
11:35 am - 11:45 am
Hendrik Hähl (Saarland University, Germany)
"Fungal Hydrophobins as Building Blocks for Pure Protein Bilayers and Vesicles"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Anna Puiggali Jou (ETH Zurich, Switzerland)
"FLight Bioprinting of Decellularized Extracellular Matrix for Cartilage Tissue Engineering"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Jung-uk Lee (Yonsei University, South Korea)
"Magnetogenetics (MG) for Wireless and Long-range Brain Stimulation"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Keynote Session: Translational Biointerfaces Towards Therapeutics
Discussion Leader: Laura De Laporte (DWI-Leibniz Institute for Interactive Materials, Germany)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
Ashutosh Chilkoti (Duke University, United States)
"Functional Biomolecular Condensates from Synthetic Intrinsically Disordered Proteins (SynIDPs)"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:25 pm
David Mooney (Harvard University, United States)
"Artificial Cells to Manufacture T Cells"
7:25 pm - 7:35 pm
Discussion
7:35 pm - 7:45 pm
Volker Mailänder (University Medicine Mainz and MPI for Polymer Research, Germany)
"Targeting of Nanocarriers: Surface Functionalization and The Protein Corona"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure