| SATURDAY |
| 1:30 pm - 4:30 pm | Arrival and Check-in |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | Epithelial Contribution to Inflammation |
| Discussion Leader: Katrina Traber (Boston University) |
| 3:15 pm - 3:30 pm | Elizabeth Hardaker (Novartis)
"In Vivo Models of Asthma Exacerbations" |
| 3:30 pm - 3:35 pm | Discussion |
| 3:35 pm - 3:50 pm | Rebecca Bauer (University of North Carolina)
"Decreased Airway Macrophage Phagocytosis in the Context of Oxidant Pollutant Exposure: Role of Interactions with Human Bronchial Epithelial Cells" |
| 3:50 pm - 4:00 pm | Discussion |
| 4:00 pm - 5:30 pm | Poster Session I |
| 5:30 pm - 7:30 pm | Innate Immune Cells |
| Discussion Leader: Michael Otto (NIAID) |
| 5:30 pm - 5:50 pm | Racquel Domingo-Gonzalez (University of Michigan)
"Prostaglandin Synthesis Compromises Neutrophil Extracellular Trap Formation Post-Bone Marrow Transplant" |
| 5:50 pm - 6:00 pm | Discussion |
| 6:00 pm - 6:20 pm | Fadie Coleman (Boston University)
"Alveolar Macrophage NF-kB-Driven Anti-Pneumococcal Lung Defense is Circumvented by Virulent Pneumococci" |
| 6:20 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:50 pm | Joel Rasmuson (Karolinska Institutet)
"Neutrophil-Induced Acute Lung Injury Involves the Kallikrein-Kinin System" |
| 6:50 pm - 7:00 pm | Discussion |
| 7:00 pm - 7:20 pm | Yaron Vagima (Israel Institute for Biological Research)
"Early Recruitment and Homing of Neutrophils to the Lung has a Beneficial Effect Against Y. pestis Airway Infection" |
| 7:20 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Host Signaling |
| Discussion Leader: Lester Kobzik (Harvard School of Public Health) |
| 9:00 am - 9:20 am | Anne Van Der Does (Karolinska Institutet)
"Pro-Resolving Activity by the HDAC-Inhibitor Phenylbutyrate Reduces Murine Lung Inflammation During Pseudomonas aeruginosa-Induced Infection" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Megan Meyer (University of North Carolina)
"Sulforaphane, an Antioxidant Found in Broccoli, Decreases Protease Levels and Activity to Lower IAV Activation, Replication, and Infection" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Jenish Patel (Mount Sinai)
"ATPase-Driven Oligomerization of RIG-I on RNA Allows Optimal Activation of Type-I Interferon" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Kristie Hilliard (Boston University)
"The Lung-Liver Axis Facilitates Innate Immunity and Survival During Pneumonia" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Novel Regulation of Immune Signaling |
| Discussion Leader: Kipyegon Kitur (Columbia University) |
| 1:30 pm - 2:20 pm | Peter Openshaw (Imperial College London)
"The Pathogenesis of Severe Influenza" |
| 2:20 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
