| SATURDAY |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session |
| 3:45 pm - 4:15 pm | Cynthia Kenyon (University of California, San Francisco, USA)
"Genes that affect aging in C. elegans" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I (presenters with last names A-M) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Metabolism and Aging |
| Discussion Leaders: Mark McCormick (The Buck Institute for Research on Aging, USA) and Dario Valenzano (Stanford University School of Medicine, USA) |
| 7:30 pm - 7:45 pm | Kathleen Fischer (Barshop Institute for Longevity and Aging Studies, USA)
"Effects of rapamycin administered late in life on healthspan in C57BL/6NIA Mice" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | James Flynn (The Buck Institute for Research on Aging, USA)
"Longitudinal Aging Studies of the Cardiovascular and Metabolic effects of Rapamycin in C57Bl6 mice"
|
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Sarah Mitchell (National Institute on Aging, USA)
"SRT2104, a molecule designed to activate SIRT1, extends lifespan and healthspan of C57BL6/J mice" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Marcelo Mori (Federal University of Sao Paulo, Brasil)
"microRNA Processing in Adipose Tissue: Role in Metabolism and Age-Related Diseases" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Samantha Solon (ANZAC Research Institute and the University of Sydney, AU)
"Macronutrient regulation, metabolism and aging in mice" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Di Chen (The Buck Institute for Research on Aging, USA)
"Synergistic lifespan extension by daf-2 rsks-1 in C. elegans" |
| 9:25 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Role of Cell Signaling and Aging |
| Discussion Leaders: Marc Lucanic (The Buck Institute for Research on Aging, USA) and William Ja (The Scripps Research Institute, USA) |
| 9:00 am - 9:15 am | Clara Correia-Melo (Institute for Ageing and Health Newcastle University, UK)
"The Senescence-associated Secretory Phenotype stabilizes Cellular Senescence via mitochondrial dysfunction and ROS generation" |
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Remi-Martin Laberge (The Buck Institute for Research on Aging, USA)
"mTOR-Dependent IL-1a Translation Controls the Senescence-Associated Secretory Phenotype" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Brett Robison (University of California, Berkeley and The Buck Institute for Research on Aging, USA)
"Proteasome abundance modulates yeast replicative lifespan"
|
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Rebecca Taylor (The Salk Institute for Biological Studies, USA)
"The UPR is a cell non-autonomous regulator of stress resistance and aging" |
| 10:15 am - 10:20 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II (presenters with last names N-Z) |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Career Perspectives: Academic vs. Industry |
| Discussion Leaders: Gordon Lithgow (The Buck Institute for Research on Aging, USA), Bita Nakhai (National Institute on Aging, USA) and Avirup Bose (Novartis Institutes for BioMedical Research, Inc., USA) |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
