| SUNDAY |
| 2:00 pm - 11:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CELL AND DEVELOPMENTAL BIOLOGY |
| Discussion Leader: Keith Gull (Oxford University) |
| 7:30 pm - 7:55 pm | Keith Gull (Oxford University)
"Introduction and Cell Surface and Development in trypanosomes" |
| 7:55 pm - 8:05 pm | Mark Carrington (Cambridge University)
"The development of epimastigote forms of Trypanosoma brucei" |
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:40 pm | Achim Schnaufer (Seattle Biomed. Res. Inst.)
"Regulation of mitochondrial function during the life cycle of African trypanosomes" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:10 pm | John Boothroyd (Stanford University)
"How Toxoplasma invades and co-opts the host cell" |
| 9:10 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Omar Harb (University of Pennsylvania)
"Real-time visualization of the Plasmodium falciparum cell cycle" |
| 9:25 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | ORGANELLE BIOGENESIS |
| Discussion Leader: Steve Hajduk (MBL, Woods Hole) |
| 9:00 am - 9:25 am | Steve Hajduk (MBL, Woods Hole)
"Introduction and trypanosome mitochondrial biogenesis" |
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:55 am | Geoff McFadden (Melbourne University)
"Plastids and mitochondria of malaria parasites" |
| 9:55 am - 10:05 am | Discussion |
| 10:05 am - 10:35 am | Coffee Break / Group Photo |
| 10:35 am - 11:00 am | Boris Striepen (University of Georgia)
"Biology of the apicomplexan plastid" |
| 11:00 am - 11:10 am | Discussion |
| 11:10 am - 11:20 am | Ke Hu (Scripps Research Institute)
"New Cytoskeletal Structures used to build a parasite" |
| 11:20 am - 11:25 am | Discussion |
| 11:25 am - 11:35 am | Andre Schneider (University of Firbourg)
"EF1A is required for mitochondrial targeting of tRNA in T.brucei" |
| 11:35 am - 11:40 am | Discussion |
| 11:40 am - 12:05 pm | Cynthia He (Yale University)
"Regulation of Golgi biogenesis in Trypanosoma brucei" |
| 12:05 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Nicole Struck (Bernhard Nocht Institiute)
"Characterization of the Golgi complex in P. falciparum" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MEMBRANE BIOLOGY |
| Discussion Leader: Scott Landfear (University of Oregon) |
| 7:30 pm - 7:55 pm | Scott Landfear (University of Oregon)
"Introduction and trypanosomatid glucose transporters" |
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:25 pm | Norma Andrews (Yale University)
"LIT1, a Leishmania amazonensis iron transporter required for intracellular growth" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:40 pm | Jay Bangs (Univ. of Wisconsin-Madison)
"Regulation of GPI valence by conditional aggregation in T.brucei" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:10 pm | Kasturi Haldar (N.Western Univ. Chicago)
"Membrane protein trafficking in Plasmodium" |
| 9:10 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Sabrina Sonda (University of Zurich)
"Essential role of MDRs in Toxoplasma gondii biology" |
| 9:25 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | HOST-CELL INVASION |
| Discussion Leader: Barbara Burleigh (Harvard) |
| 9:00 am - 9:25 am | Barbara Burleigh (Harvard)
"Introduction and T.cruzi invasion of host cells" |
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:55 am | Dominique Soldati (University of Geneva)
"Motility and invasion by Toxoplasma" |
| 9:55 am - 10:05 am | Discussion |
| 10:05 am - 10:35 am | Coffee Break |
| 10:35 am - 11:00 am | David Sibley (Washington Univ., St. Louis)
"Calcium signalling controls invasion and egress by Toxoplasma" |
| 11:00 am - 11:10 am | Discussion |
| 11:10 am - 11:20 am | Florence Dzierszinski (Univ. of Pennsylvania)
"Presentation of Toxoplasma antigens via the endogenous MHC class 1 pathway" |
| 11:20 am - 11:25 am | Discussion |
| 11:25 am - 11:50 am | Ana Rodriguez (New York University)
"Regulation and signaling of Plasmodium sporozoite migration, exocytosis and invasion" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Alida Coppi (New York University)
"The role of proteoglycans in Plasmodium invasion and migration" |
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Steven O’Hara (Mayo Clinic)
"Host-cell membrane protrusion by C. parvum requires membrane translocation of SGLT1 and AQP1" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TRICHOMONADS AND AMOEBAE |
| Discussion Leader: Jan Tachezy (Charles Univ., Czech Republic) |
| 7:30 pm - 7:55 pm | Jan Tachezy (Charles Univ., Czech Republic)
"Introduction and Organelle Biogenesis" |
| 7:55 pm - 8:00 pm | Discussion |
| 7:55 pm - 8:20 pm | Jorge Tovar-Torres (University of London)
"Mitosomes of Entamoeba histolytica: biology and evolutionary significance" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:55 pm | Zac Cande (UC, Berkeley)
"A tale of two nuclei: Mitosis in Giardia" |
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:10 pm | Upinder Singh (Stanford University)
"Identification of virulence determinants in Entamoeba histolytica" |
| 9:10 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Katrin Henze (Heinrich-Heine University)
"Rubrerythrin, an FeS-protein of uncertain function in the hydrogenosomes of trichomonads" |
| 9:25 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | DRUG DISCOVERY |
| Discussion Leader: Margaret Phillips (Univ. Texas S.Western) |
| 9:00 am - 9:25 am | Margaret Phillips (Univ. Texas S.Western)
"Introduction and Therapeutic targets in parasites" |
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:55 am | Kip Guy (St. Jude Children's Hospital)
"Screening approaches to lead discovery for kinetoplastids" |
| 9:55 am - 10:05 am | Discussion |
| 10:05 am - 10:35 am | Coffee Break |
| 10:35 am - 10:45 am | Doron Greenbaum (Univ. of Pennsylvania)
"Identifying the malarial Cys protease involved in rupture from the RBC by a systems biology approach" |
| 10:45 am - 10:50 am | Discussion |
| 10:50 am - 11:00 am | Alexandra Lusher (University of Bern)
"Adenosine kinase in purine salvage and susceptibility to adenosine antimetabolites in T. brucei" |
| 11:00 am - 11:05 am | Discussion |
| 11:05 am - 11:30 am | Bill Charman (Monash Univ., Melbourne)
"Synthetic peroxides for malaria therapy" |
| 11:30 am - 11:40 am | Discussion |
| 11:40 am - 11:50 am | Mohamed Sanhory (Sanhorial Medical)
"Treatment Of Cutaneous Leishmaniasis" |
| 11:50 am - 11:55 am | Discussion |
| 11:55 am - 12:20 pm | Christian Burri (Swiss Tropical Inst.)
"Clinical trials in Africa" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | VECTOR BIOLOGY |
| Discussion Leader: Anthony James (UC, Irvine) |
| 7:30 pm - 7:55 pm | Anthony James (UC, Irvine)
"Introduction and Anopheles gene expression" |
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:10 pm | Margareth Capurro (University of Sao Paulo)
"Differential gene expression by Plasmodium and dengue infected Aedes aegypti" |
| 8:10 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:40 pm | Laura Harrington (Cornell University)
"New insights into blood feeding behavior and ecology of the dengue vector, Aedes aegypti" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:10 pm | Paul Bates (Liverpool University)
"The role of the sand fly and Leishmania molecules in Leishmania infections" |
| 9:10 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Pedro Oliveira (Univ. of Rio de Janeiro)
"A novel heme degradation pathway in Rhodnius prolixus" |
| 9:25 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | COMPARATIVE GENOMICS AND METABOLOMICS |
| Discussion Leader: David Roos (U-Penn) |
| 9:00 am - 9:25 am | David Roos (U-Penn)
"Introduction and new tools for metabolic pathway prediction" |
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:55 am | Alan Fairlamb (Dundee, UK)
"Comparing and exploiting metabolomic predicitions" |
| 9:55 am - 10:05 am | Discussion |
| 10:05 am - 10:35 am | Coffee Break |
| 10:35 am - 10:45 am | Thomas Naderer (University of Melbourne)
"Virulence of L.major requires the gluconeogenic enzyme fructose-1,6-bisphosphatase" |
| 10:45 am - 10:50 am | Discussion |
| 10:50 am - 11:15 am | L. Aravind (NIH)
"Transcription machineries of protozoan pathogens" |
| 11:15 am - 11:25 am | Discussion |
| 11:25 am - 11:50 am | Tom Templeton (Cornell University)
"Genomics and the host-parasite interactions of Plasmodium" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Pascal Mäser (University of Bern)
"Comparative genomics between parasites and free-living eukaryotes" |
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Jeroen Saeij (Stanford)
"Identification of parasite genes responsible for Toxoplasma strain-specific differences on host cell gene expression" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | GENE EXPRESSION AND EPIGENETIC REGULATION |
| Discussion Leader: Piet Borst (Netherlands Cancer Inst.) |
| 7:30 pm - 7:55 pm | Piet Borst (Netherlands Cancer Inst.)
"Introduction and base-J and gene regulation in T.brucei" |
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:25 pm | Gloria Rudenko (Oxford University)
"VSG expression site control in Trypanosoma brucei" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:40 pm | David Landeira (CSIC (Spanish National Research Council))
"Nuclear dynamics of developmentally regulated transcriptional domains in T.brucei" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 8:55 pm | Christian Janzen (Rockefeller University)
"Selective methylation of histone H3 by two DOT1 homologues is important for cell cycle regulation in T. brucei" |
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:25 pm | Artur Scherf (Pasteur Inst., Paris)
"Epigenetic factors that control antigenic variation in P. falciparum" |
| 9:25 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
