Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Global Impact of Parasitic Pathogens on Human Health
7:40 pm - 8:10 pm
"Challenges and Successes: Discovering New Antimalarial Treatments and Chemoprotectants"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"The Skin: An Overlooked Reservoir of African Trypanosomes"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Developing Solutions for Chagas Disease: The Importance of Understanding Parasite Biology"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Genome and Genes, Expression and Regulation
9:00 am - 9:20 am
"Malaria Parasite DNA Modifications Revisited"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Manipulaiton of Host Gene Expression and Signaling by Toxoplasma"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Hymenolepis Diminuta as a Parasite Model for Stem Cells and Regeneration"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"The Parasitic Love Machine: Understanding Schistosome Sexual Reproduction on a Molecular Level"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Metabolic Changes, Transcriptional Control and Regulation of Stage Conversion in Entamoeba histolytica : Linking It All Together"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Integrating and Interrogating Big (Pathogen) Datasets from the Lab, Field and Clinic"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"An ER-Resident Calcium Binding Protein Is Required for Egress and Invasion of Malaria Parasites"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"1 + 1 = 1: A Forward Screen for Novel Plastid Biogenesis Genes in Malaria Parasites"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Pathogenesis and Host Cell Remodeling
7:30 pm - 7:50 pm
"Trichomonas vaginalis Pathogenesis: Surface and Secreted Factors"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Exploring Metabolic Flexibility and Adaptation in Intracellular Trypanosoma cruzi Amastigotes"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Moving in and Renovating: Invasion and Remodeling of the Human Erythrocyte by the Malaria Parasite"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"CryoEM Reveals Translocation Mechanism in Malaria Parasite Effector Export"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"A Divergent Secreted Kinase Regulates Membrane Ultrastructure of the Toxoplasma Parasitophorous Vacuole"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Coordinated Expression of Multi-Copy Gene Families in the Human Malaria Parasite Plasmodium falciparum "
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Understanding Mechanisms of Cerebral Malaria Pathogenesis"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"A GC-Rich Non-Coding RNA Acts as Trans-Activator of Monoallelic Expression in Plasmodium falciparum "
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"The Increasing 'Diversity-Space' of Trypanosoma brucei Antigenic Variation"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Exploring the Dynamics of Antigenic Variation and VSG Diversification in the T. brucei Extravascular Niche"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"A VSG Allelic Exclusion Complex"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Divide et Impera : Chromosome Segregation in Trypanosoma brucei , a Target Deconvolution View"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Plasmodium berghei Sporozoite Infection of Anopheles stephensi Salivary Glands"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Clinical Evaluation of a New Vaccine Against Malaria"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"An Essential Mitochondrial Fucosyl Transferase in Leishmania "
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"How Cancerous Tapeworms Work"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Neuronal Defense Mechanisms Against Toxoplasma gondii Infection"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"The Circadian Clock in Immune Cells Controls the Magnitude of Leishmania Parasite Infection"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Metabolic Vulnerabilities and Impact on Life Cycle
9:00 am - 9:20 am
"Metabolic Vulnerability of Parasites Probed Through Exposure to Drugs"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Exploiting Phenotypic Hits to Discover P. falciparum Weaknesses"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Pyruvate Kinase II Is Required for Apicoplast Maintenance"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"InsP7 Protein Targets Reveal Distinct Roles in Proliferative Stages of Trypanosoma cruzi "
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Can We Build a Genetic Trap for Drug Resistant Malaria Parasites?"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Systems Approaches to Uncover Mechanisms of Drug Resistance in Apicomplexan Parasites"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Diet-Induced Oxidative Stress Impair Plasmodium Liver Infection"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Mechanosensation in Trypanosomes: Physical Cues to Sense the World Around Them"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Parasite and Host Cell Communication
7:30 pm - 7:50 pm
"Cell-Cell Communication in Trypanosoma brucei "
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Host-Seeking Behaviors of Parasitic Nematodes"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Entamoeba histolytica Trogocytosis and Protection from Innate Immune Factors"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Understanding Cachexia Through Host-Parasite Interactions"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Sleeping Sickness Is a Circadian Disorder"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Exploiting the Host Haemoglobin Degradation Pathway for Malaria and Schistosomiasis Drug Discovery"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Computational Approaches to Accelerate Drug Discovery"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Data Visualization and Analysis to Empower Antimalarial Drug Discovery"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Redox Controlled Functions of Apicomplexan Parasites"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Identifying Novel Targets Through Phenotypic Screening"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Drug Discovery and Early Development for Protozoan Parasitic Diseases Therapeutics"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Identification of Anti-Wolbachial Compounds to Cure Parasitic Worm Disease"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Doxycycline Has Distinct Apicoplast-Specific Mechanisms of Antimalarial Activity"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Challenges to Effective Therapy
7:30 pm - 7:50 pm
"The Arms Race Between Host and Parasite: Serum Resistance in Zoonotic Trypanosomes"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Mutagenesis in Plasmodium falciparum "
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Harnessing Genomics for Understanding Malaria Drug Resistance"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Emerging Southeast Asian PfCRT Mutations Confer P. falciparum Resistance to the First-Line Antimalarial Piperaquine"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"K13 C580Y Mutation Is Not Linked to Increased Artemisinin Treatment Failures in a P. falciparum Cross"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure