| SATURDAY |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Vaccine Development |
| Discussion Leaders: Jon Blevins and Philip Adams |
| 3:45 pm - 4:15 pm | Kristel Lourdault (University of California, Los Angeles)
"Oral Immunization with LigA Provides Protective Immunity Against Challenge with Leptospira interrogans Serovar Copenhageni"
|
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Spirochete-Host Interactions: How the Host Responds |
| Discussion Leaders: Job Lopez and Priya Jayaraman |
| 7:30 pm - 7:50 pm | Padmapriya Sekar (The University of Toledo)
"Assessment of Cellular Immune Responses to Acute and Persistent Borrelia burgdorferi Infection in Skin"
|
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Kenneth Bramwell (University of Utah)
"Lysosomal Beta-Glucuronidase Regulated Lyme and Rheumatoid Arthritis Severity"
|
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Amy Devlin (North Carolina State University)
"Modulation of Leptospira interrogans Infection by the Anti-Inflammatory Cytokine IL-10"
|
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Robert Lochhead (University of Utah)
"MicroRNA miR-146a Provides Feedback Regulation of Lyme Arthritis During Infection with Borrelia burgdorferi"
|
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Spirochete Infectivity Determinants: How Do They Promote Virulence? |
| Discussion Leaders: Jarlath Nally and Yi-Pin Lin |
| 9:00 am - 9:20 am | Karen Evangelista (Medical College of Wisconsin)
"Identification of Leptospira interrogans Adhesins and Host Cell Surface Receptors"
|
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Azad Eshghi (Institut Pasteur)
"A Leptospira lpxD Mutant is Attenuated in Virulence and Protects Gerbils Against Lethal Infection"
|
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Laura Ristow (Medical College of Wisconsin)
"Analysis of the Role of P66, Borrelia burgdorferi's β3 Integrin Ligand, in Mammalian Infection"
|
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Sunny Jain (University of Central Florida)
"Molecular Dissection of a Borrelia burgdorferi In Vivo Essential Purine Transport System"
|
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Spirochete Motility: Sensing and Motility Dynamics |
| Discussion Leaders: Mollie Jewett and Joshua Dunn |
| 1:30 pm - 1:50 pm | Michael Harman (University of Arizona)
"The Viscous Dynamics of Pathogenic Spirochetes Reveal Flagellar Torque and Drag"
|
| 1:50 pm - 2:00 pm | Discussion |
| 2:00 pm - 2:20 pm | Ki Hwan Moon (East Carolina University)
"Role of CheD in Borrelia burgdorferi: Bacterial Chemotaxis and Pathogenesis" |
| 2:20 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
