Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: The Role of Amino Acids in Osteoblast Differentiation and Bone Formation - More Than Just Protein Synthesis
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
"The Role of Amino Acids in Osteoblast Differentiation and Bone Formation - More Than Just Protein Synthesis"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Mechanisms and Stem Cells Regulating the Skeleton
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 7:55 pm
"SOX4 Inhibits Trabecular Bone Formation in Female Mice"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Periosteum-Derived Cells From Craniofacial Area Could Serve as a Cell Source for Bone Tissue Engineering Purposes"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"ADGRG6 Maintains Cartilage Homeostasis Through Gs/cAMP Signaling"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"The Primary Cilium Mediates BMP Signaling in Periosteal Cell Differentiation and Mechanotransduction"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Nf1 Deficiency-Induced Senescence in Osteoprogenitor Cells as a New Therapeutic Target for NF1 Pseudarthrosis"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"An Integrated Single-Cell Atlas of the Skeleton From Development Through Adulthood"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Paradoxical Effect of Frizzled2-Fc on Bone Mass for the Treatment of Osteogenesis Imperfecta"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Metabolism and Microenvironment in Bone Homeostasis and Pathology
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:25 am
"Bone-Anabolic Cholinergic Neurons Maintain the Osteocyte Syncytium"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"A Specialized Metabolic Pathway Regulates Osteoblast Citrate Deposition in Bone Mineral to Impact Mechanical Strength"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"PD-L1 Expression Promotes Bone Marrow Immunosuppression and Bone Loss with Diet-Induced Obesity"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Characterizing Glycogen Metabolism’s Role in Cartilage Development & in Mutant IDH Chondrosarcomas"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Conditional Deletion of the Catalytic Subunit of NADPH Oxidase 2 in Late Osteoblasts/Osteocytes Results in Mild Osteopenia in Female Mice"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Influence of B Cells in a Large-Scale Bone Regeneration Mouse Model"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"De novo Glutathione Biosynthesis is Essential for Osteoblast Differentiation by Establishing a Pro-Osteogenic Redox Environment"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: A Roadmap to Being Successful in Academia
1:30 pm - 2:30 pm
Panel Discussion
A Roadmap to Being Successful in Academia
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes