Towards New Horizons in Calcium Signaling: Bridging the Gap Between Molecular Mechanisms and Therapeutic Interventions

Calcium ions play a crucial role in various physiological processes and can also contribute to pathological conditions when their balance is disrupted. In physiology, calcium ions are involved in numerous cellular functions, including cell growth, differentiation, migration, enzyme activation, and signal transduction. To this end, calcium homeostasis is tightly regulated within cells primarily through the interplay of transporters, channels, and calcium-binding proteins.

Dysregulated calcium signaling has been implicated in a number of pathologies affecting various organ systems. Diseases such as heart failure, Parkinson's and Alzheimer's disease, autoimmunity, as well as cancer are all linked to disturbed calcium homeostasis. However, the molecular mechanisms underlying these calcium-controlled disorders are not fully understood. Gaining a deeper understanding of the complex mechanisms of calcium signaling, from cells to organs, will provide insights for the development of novel therapeutic strategies and technologies.

The primary objective of this conference is to foster a collaborative environment by bringing together global leaders in calcium research, graduate students, and scientists at the early stages of their independent careers. The main aim is to advance our comprehension of the molecular mechanisms underlying calcium signaling and homeostasis, explore the physiological and pathological impacts of calcium signals, and discuss strategies for targeting calcium channels to achieve therapeutic benefits.