| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | "Keynote Talks" |
| Discussion Leader: Eric R. Fearon (University of Michigan) |
| 7:30 pm - 8:30 pm | Harold Varmus (Memorial Sloan-Kettering Cancer Center) |
| 8:30 pm - 9:30 pm | David Livingston (Dana-Farber Cancer Institute)
"Recent Developments in the Analysis of BRCA1 Function" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00am - 12:30 pm | "Oncogene Pathways I" |
| Discussion Leader: Julian Downward (Imperial Cancer Research Fund) |
| 9:00 am - 9:30 am | Julian Downward (Imperial Cancer Research Fund) |
| 9:30 am - 10:00 am | Paul Sternberg (HHMI, Caltech)
"Regulation of the C. elegans RAS Pathway" |
| 10:00 am - 10:30 am | Lynda Chin (Harvard Medical School)
"Oncogene Signaling in Tumor Maintenance" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:30 am | Tak Mak (Ontario Cancer Institute, University of Toronto)
"Genetic Dissection of the PTEN and p53 Pathways" |
| 11:30 am - 12:00 pm | Tian Xu (HHMI, Yale University) |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | "Oncogene Pathways II" |
| Discussion Leader: James Downing (St. Jude Children's Res. Hosp) |
| 7:30 pm - 8:00 pm | James Downing (St. Jude Children's Res. Hosp) |
| 8:00 pm - 8:30 pm | Utpal Banerjee (UCLA) |
| 8:30 pm - 9:00 pm | Leonard Zon (HHMI, Children's Hospital of Boston) |
| 9:00 pm - 9:30 pm | Pier Paolo Pandolfi (Memorial Sloan-Kettering Cancer Center) |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00am - 12:30 pm | "Tumor Suppressor Pathways I" |
| Discussion Leader: Jacqueline Lees (MIT) |
| 9:00 am - 9:30 am | Jacqueline Lees (MIT) |
| 9:30 am - 10:00 am | Piotr Sicinski (Dana-Farber Cancer Institute)
"In Vivo Functions for D-Cyclins" |
| 10:00 am - 10:30 am | Nicholas Dyson (MGH Cancer Center) |
| 10:30 am | Coffee Break |
| 11:00 am - 11:30 am | Iswar Hariharan (MGH Cancer Center)
"Genes That Restrict Growth and Cell Proliferation in Drosophila and Humans" |
| 11:30 am - 12:00 pm | Brian Dynlacht (Harvard University)
"RB, E2F, and Transcriptional Control of the Cell Cycle." |
| 12:00pm - 12:30 pm | Beverly Emerson (Salk Institute) |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | "Tumor Suppressor Pathways II" |
| Discussion Leader: Tyler Jacks (MIT) |
| 7:30 pm - 8:00 pm | Tyler Jacks (HHMI, MIT) |
| 8:00 pm - 8:30 pm | W. Brent Derry (UC-Santa Barbara) |
| 8:30 pm - 9:00 pm | Yusuke Nakamura (University of Tokyo) |
| 9:00 pm - 9:30 pm | Ronald DePinho (Dana-Farber Cancer Institute)
"Modeling Cancer and Cancer Genomes" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00am - 12:30 pm | "Tumor Suppressor Pathways III" |
| Discussion Leader: Stuart Aaronson (Mt. Sinai School of Medicine) |
| 9:00 am - 9:30 am | Stuart Aaronson (Mt. Sinai School of Medicine) |
| 9:30 am - 10:00 am | Brooke McCartney (University of North Carolina)
"A Model Systems Approach to Functional Studies of the APC Tumor Suppressor" |
| 10:00 am - 10:30 am | Kenneth Cadigan (University of Michigan) |
| 10:30 am | Coffee Break |
| 11:00 am - 11:30 am | Scott Emmons (Albert Einstein College of Medicine)
"Role of the Transcriptional Mediator Complex in Wnt Pathway Activation of Hox Genes" |
| 11:30 am - 12:00 pm | Walter Birchmeier (Max Delbrueck-Center for Molecular Medicine) |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | "Epigenetics, DNA Methylation, and Transcriptional Memory" |
| Discussion Leader: Stephen Baylin (Johns Hopkins Sch. Of Med) |
| 7:30 pm - 8:00 pm | Jasper Rine (UC Berkeley) |
| 8:00 pm - 8:30 pm | Timothy Bestor (Columbia University)
"Cytosine Methylation and Genomic Instability in Cancer" |
| 8:30 pm - 9:00 pm | Stephen Baylin (Johns Hopkins University) |
| 9:00 pm - 9:30 pm | Ramin Shiekhattar (Wistar Institute)
"Linking Chromatin Remodeling and Sister Chromatid Cohesion" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00am - 12:30 pm | "Tumor Suppressor Pathways IV" |
| Discussion Leader: Luis Parada (UT Southwestern) |
| 9:00 am - 9:30 am | William Kaelin (HHMI, Dana Farber Cancer Institute) |
| 9:30 am - 10:00 am | Luis Parada (UT Southwestern)
"NF Models of Brain Tumors" |
| 10:00 am - 10:30 am | Andrea McClatchey (MGH Cancer Center, Harvard Med School)
"Merlin for Muggles" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:30 am | Richard Fehon (Duke University)
"Tumor Suppression and the Apical Junctional Domain" |
| 11:30 am - 12:00 pm | Robert Wechsler-Reya (Duke University)
"Regulation and Dysregulation of Cerebellar Growth by the Sonic Hedgehog Signaling Pathway" |
| 12:00 am - 12:30 pm | Askok Venkitaraman (University of Cambridge)
"Mitotic Checkpoint Dysfunction and Chromosomal Instability" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | "Genetic Instability" |
| Discussion Leader: Frederick Alt (HHMI, Children's Hospital of Boston) |
| 7:30 pm - 8:00 pm | Christoph Lengauer (Johns Hopkins University)
"Chromosomal Instability in Colorectal Cancers" |
| 8:00 pm - 8:30 pm | Frederick Alt (HHMI, Children's Hospital of Boston)
"Interplay Between Non-homologous End-Joining Proteins and Cell Cycle Checkpoint Pathways in Normal Development and Tumor Suppression" |
| 8:30 pm - 9:00 pm | Richard Fishel (Kimmel Cancer Center, Thomas Jefferson University)
"Connecting the Mechanism of Mismatch Repair to Carcinogenesis" |
| 9:00 pm - 9:30 pm | Anindya Dutta (Brigham & Women's, Harvard Medical School)
"Mechanisms to Prevent Re-Replication in Cancer Cells" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
