Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Skeletal and Joint Development
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
"Modular Cartilaginous Template Development: A Way to Develop a Multifunctional Bone"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Wnt5a Signaling in Limb Development and Autosomal Dominant Robinow Syndrome"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Evolution and Regeneration of the Limb
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Oxygen-Sensitivity and Evolution of Limb Regeneration"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Lizard Tails as Instructive Models of Blastema-Based Cartilage Regeneration"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Salamander Limb Regeneration - Regulation and Evolution"
11:25 am - 11:35 am
Discussion
11:35 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Short Talk Selected from Poster Abstracts
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Late-Breaking Topic
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Signalling Inside and Outside the Cell
7:30 pm - 7:50 pm
"Intrinsic Articular Cartilage Repair is Driven by Matrix Bound Growth Factors"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Ciliary Variants Reveal Requirements for Chondrogenic and Osteogenic Differentiation of Cranial Neural Crest Cells"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Genomics and Epigenomics: Nature and Nurture
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Epigenomics in Cartilage Development and Disease: MicroRNAs and More"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Epigenetic Regulation of Aging and Osteoarthritis"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"From Osteoarthritis Genetics to the Clinic?: Identifying Biological Pathways and Drug Repurposing Possibilities"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"From Genomics and Epigenomics to Disease Phenotyping OA"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Extracellular Matrix in Health and Disease
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"The Cartilage Micromechanical Environment: Linking Extracellular Matrix to Tissue Function"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Role and Mechanisms of Cartilage Calcification in OA"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Short Talk Selected from Poster Abstracts
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
Short Talk Selected from Poster Abstracts
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Mechanobiology and Biomechanics
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Modeling Biomechanics in the Zebrafish Jaw Throughout the Life Span: Influences of Aging and Genetic Mutations"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Predicting Cartilage Adaptation in KOA Patients: Where in Vitro Research Meets Multi-Scale Modeling"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Subchondral Bone Contributions to Joint Homeostasis and Disease"
11:25 am - 11:35 am
Discussion
11:35 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Short Talk Selected from Poster Abstracts
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Tissue Engineering and Stem Cell Biology
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"A Platform to Evaluate Fetal Chondrocyte Gene Regulatory Networks in Human Chondrocytes"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Mechanoregulation of Joint Tissues in Development and Disease"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Short Talk Selected from Poster Abstracts
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Late-Breaking Topic
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Cartilage Disease: Pathogenesis and Drug Discovery
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Matrix Protein Anabolic Indices Identify Regenerative Cartilage Small RNAs"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Advancing Osteoarthritis Therapeutics by Defining Cartilage Progenitors and their Regulatory Niche"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Electromechanical Grading of Human Tibia Plateau Cartilage to Associate Transcriptome Patterns with OA-Pathology"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Drug Repurposing in Rare Bone Diseases"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Emerging Technologies and Models
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Mass-Production of Advanced Micromaterials for Scalable Production of Modular Living Tissues"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Multiphoton Microfabrication and Micropatterning (MMM) Platform Technology for Cell Niche Engineering"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Short Talk Selected from Poster Abstracts
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Late-Breaking Topic
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure