Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Skeletal and Joint Development
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
"Modular Cartilaginous Template Development: A Way to Develop a Multifunctional Bone"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Wnt5a Signaling in Limb Development and Autosomal Dominant Robinow Syndrome"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Evolution and Regeneration of the Limb
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Oxygen-Sensitivity and Evolution of Limb Regeneration"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Lizard Tails as Instructive Models of Blastema-Based Cartilage Regeneration"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Salamander Limb Regeneration - Regulation and Evolution"
11:25 am - 11:35 am
Discussion
11:35 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Short Talk Selected from Poster Abstracts
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Late-Breaking Topic
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hourâ„¢ is open to all conference participants.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Signalling Inside and Outside the Cell
7:30 pm - 7:50 pm
"Intrinsic Articular Cartilage Repair is Driven by Matrix Bound Growth Factors"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Ciliary Variants Reveal Requirements for Chondrogenic and Osteogenic Differentiation of Cranial Neural Crest Cells"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Genomics and Epigenomics: Nature and Nurture
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Epigenomics in Cartilage Development and Disease: MicroRNAs and More"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Epigenetic Regulation of Aging and Osteoarthritis"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"From Osteoarthritis Genetics to the Clinic?: Identifying Biological Pathways and Drug Repurposing Possibilities"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"From Genomics and Epigenomics to Disease Phenotyping OA"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Extracellular Matrix in Health and Disease
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"The Cartilage Micromechanical Environment: Linking Extracellular Matrix to Tissue Function"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Role and Mechanisms of Cartilage Calcification in OA"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Short Talk Selected from Poster Abstracts
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
Short Talk Selected from Poster Abstracts
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Mechanobiology and Biomechanics
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Modeling Biomechanics in the Zebrafish Jaw Throughout the Life Span: Influences of Aging and Genetic Mutations"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Predicting Cartilage Adaptation in KOA Patients: Where in Vitro Research Meets Multi-Scale Modeling"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Subchondral Bone Contributions to Joint Homeostasis and Disease"
11:25 am - 11:35 am
Discussion
11:35 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Short Talk Selected from Poster Abstracts
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Tissue Engineering and Stem Cell Biology
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"A Platform to Evaluate Fetal Chondrocyte Gene Regulatory Networks in Human Chondrocytes"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Mechanoregulation of Joint Tissues in Development and Disease"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Short Talk Selected from Poster Abstracts
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Late-Breaking Topic
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Cartilage Disease: Pathogenesis and Drug Discovery
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Matrix Protein Anabolic Indices Identify Regenerative Cartilage Small RNAs"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Advancing Osteoarthritis Therapeutics by Defining Cartilage Progenitors and their Regulatory Niche"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Electromechanical Grading of Human Tibia Plateau Cartilage to Associate Transcriptome Patterns with OA-Pathology"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Drug Repurposing in Rare Bone Diseases"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Emerging Technologies and Models
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Mass-Production of Advanced Micromaterials for Scalable Production of Modular Living Tissues"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Multiphoton Microfabrication and Micropatterning (MMM) Platform Technology for Cell Niche Engineering"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Short Talk Selected from Poster Abstracts
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
Late-Breaking Topic
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure