Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Cell Death in Infection, Immunity and Inflammation
3:45 pm - 3:55 pm
"Cytotoxic CD4+ T Cells and IFN-g Orchestrate the Induction of Apoptosis Important for Granuloma Formation during Salmonella Typhimurium Infection"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"Calcium Channel Blockers Reduce Apoptotic Body Mediated SARS-CoV-2 Cell-to-Cell Spread and Subsequent Cytokine Storm"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Unexpected Function of Inflammatory Molecules for Axon Pruning in Neurons"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Crosstalk between Metabolism and Cell Death
7:30 pm - 7:40 pm
"Tumor Lipid Composition Impacts Susceptibility to Ferroptosis"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Non-Necroptotic Roles of Hepatocyte MLKL in MASLD"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Ferroptotic Injury Drives Two Distinct Proximal Tubule Cell Fate Trajectories in Maladaptive Kidney Repair"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Identification of Genes and Pathways that Protect AML12 Cells from Death During Ischemia-Reperfusion Injury"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Interplay of Aging on Polyunsaturated Fatty Acid Oxidative Metabolism and Ferroptosis in Neurodegeneration in C. Elegans"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"A Deadly Choice: Oxidation Controlled Amyloid Assembly of The Cell Death Regulator Caspase-8 Drives Necroptosis."
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Elucidating the Role of the Endonuclease XPF in Sensitizing Melanoma Cells to Ferroptotic Cell Death"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Castration Induces Regression of Prostate Luminal Epithelial Cells through Ferroptosis"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Therapeutic Approaches Targeting Cell Death in Disease
9:00 am - 9:10 am
"Development of a First-in-Class RIPK1 Degrader to Enhance Antitumor Immunity"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"MOMP-Dependent Mitophagy Limits Radiotherapy-Induced Inflammation in Breast Cancer"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Linker Cell-Type Death in Development and Neurodegeneration"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Interferon-Stimulated Gene 15 as a Novel Regulator of Cell Death"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Early Cytokine-Driven Adaptation of Survival Pathways in Lymphoid Cells During Targeted Therapies"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"The Fate of Chromatin in Regulated Cell Death"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"NINJ1-Driven Necrosis Requires Alterations in Cell Morphology"
10:40 am - 10:45 am
Discussion
10:45 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Empowering the Next Generation: Mentorship and Career Development in Cell Death Research
1:30 pm - 1:40 pm
Introduction by Discussion Leader
1:40 pm - 2:05 pm
"Insights on Cell Death Research"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:30 pm
General Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
