SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Lecture |
| Discussion Leader: Tarek Abbas (University of Virginia) |
3:45 pm - 4:15 pm | Johannes C. Walter (Harvard Medical School) "A novel, S phase-specific proteolysis pathway" |
4:15 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I (last names A-O) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Transcription and S Phase Regulation |
| Discussion Leaders: Philipp Kaldis (Institute of Molecular and Cell Biology) and Yong-Wei Zhang (National Cancer Institute) |
7:30 pm - 7:45 pm | Con Sullivan (Maine Institute for Human Genetics and Health) "FOXM1 and CDC25A interact at the transcriptional and post-translational levels to regulate the G1/S cell cycle transition" |
7:45 pm - 7:55 pm | Discussion |
7:55 pm - 8:10 pm | Gavin D. Grant (Dartmouth Medical School) "Live cell monitoring of periodic gene expression in synchronous human cells identifies forkhead genes involved in cell cycle control" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:35 pm | Volkan Sayin (Gothenburg University) "ZFP148 permits cell proliferation under oxidative conditions by attenuating p53 repression of cell cycle genes" |
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 9:00 pm | Jean M. Davidson (University of North Carolina, Chapel Hill) "A Novel Oncogenic Sensor Revealed by Blocking S Phase-Coupled E2f1 Destruction" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Seetha V. Srinivasan (Columbia University) "Aberrant Myc Expression alters DNA Replication Dynamics" |
9:25 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Proteolysis and Mitosis |
| Discussion Leaders: Buzz Baum (University College London) and Andrew Holland (Ludwig Institute for Cancer Research, UCSD) |
9:00 am - 9:15 am | Tarek Abbas (University of Virginia) "Differential ubiquitylation of CRL4Cdt2 substrates by UBCH8 and UBE2G ubiquitin conjugating enzymes" |
9:15 am - 9:25 am | Discussion |
9:25 am - 9:40 am | Subhashini Sadasivam (Dana-Farber Cancer Institute) "B-Myb-MuvB Complex Regulates the Cell Cycle Dependent Expression of Genes Required for Mitosis" |
9:40 am - 9:50 am | Discussion |
9:50 am - 10:05 am | Maggie P.C. Ma (Children's Medical Research Institute) "The sorting nexin 9 (SNX9) subfamily is required for mitotic progression" |
10:05 am - 10:15 am | Discussion |
10:15 am - 10:30 am | Gabriel E. Neurohr (Center for Genomic Regulation) "A midzone-based ruler promotes chromosome segregation by adjusting the condensation of long chromosomes to the size of the spindle" |
10:30 am - 10:40 am | Discussion |
10:40 am - 10:55 am | Seo Young Kim (Oklahoma Medical Research Foundation) "IPL1/Aurora B kinase inhibits bipolar spindle assembly during meiotic prophase" |
10:55 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session II (last names P-Z) |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentoring Session: How to Obtain a Job in Academia |
| Discussion Leaders: Nicole Francis (Harvard Medical School), David Pellman (Dana Farber Cancer Institute), Johannes C. Walter (Harvard Medical School), and Philipp Kaldis (Institute of Molecular and Cell Biology) |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |