| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:40 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:40 pm - 4:30 pm | Getting Through The Cell Cycle |
| Discussion Leader: Gabriel Nuehohr (MIT) |
| 3:40 pm - 3:55 pm | Tony Ly (University of Dundee)
"Large Scale Analysis of Protein and RNA Expression over the Mammalian Cell Cycle"
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| 3:55 pm - 4:00 pm | Discussion |
| 4:00 pm - 4:15 pm | Amy Johnson (Stanford University)
"Redefining the Mammalian Restriction Point with Single-Cell Analysis" |
| 4:15 pm - 4:20 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Cell Cycle & Cancer |
| Discussion Leader: Philipp Kaldis (IMCB) |
| 7:30 pm - 7:45 pm | Juliana Galvao (Instituto Butantan)
"Phorbol Ester-responsive PKC Isoforms Induce Cell Death in Human Embryonic Kidney Cell Line (HEK 293) Displaying a Ras-driven Malignant Phenotype" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Yoon Choi (Dana Farber Cancer Institute)
"Differential Requirements of D-cyclins in Cancer and Normal Cells" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Keisha Hardeman (Vanderbilt University)
"Targeting Altered Redox Metabolism in Lapatinib-resistant Breast Cancer" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Jennifer Devlin (Peter Maccallum Cancer Centre)
"Inhibitors of the PI3K/AKT/mTOR signaling pathway and RNA polymerase I transcription cooperate to suppress ribosome biogenesis and kill Myc-driven B-lymphoma cells" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Matheus Dias (Instituto Butantan)
"Mechanisms of FGF2 toxicity in Ras-driven malignant cells: cell division blockage and proteotoxic stress" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:30 pm | General Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Cell Homeostasis and Proliferation |
| Discussion Leader: Dominic Moon (NIH) |
| 9:00 am - 9:15 am | Joey Puccini (University of Adelaide)
"Caspase-2 Function in the Maintenance of Genomic Stability and Tumor Suppression" |
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Quincy Justman (Harvard University)
"How does the S. cerevisiae cell cycle respond to environmental change?" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Helen Matthews (University College London)
"Mitosis in a box: how the extra-cellular matrix supports cell division" |
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Deepak Jha (University of North Carolina, Chapel Hill)
"A novel role of Set2-mediated histone methylation in regulating DNA damage response" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Vijaya Pandey (ICGEB)
"Role of epigenetic alterations in onco-virus related carcinogenesis" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Valentina Cianfanelli (University of Tor Vergata)
"Ambra1: a pro-autophagic factor regulating cell proliferation and tumorigenesis" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Keynote Address |
| Discussion Leader: Jean Davidson (Stanford University) |
| 1:30 pm - 2:20 pm | Anindya Dutta (University of Virginia)
"Short RNAs in differentiation and cancer" |
| 2:20 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
