Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Molecular and Cellular Mechanisms of Cell Polarity
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:40 pm
"Dissecting the Roles of Antagonistic Interactions Between Polarity Factors in the Apical-Basal Polarisation of Epithelial Cells"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
"Tracing the Source of Embryonic Polarity in the Early Oocyte: Regulation of Symmetry Breaking and Molecular Condensation by a Conserved Centrosome MTOC Machinery"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Polarization and Cytoskeleton
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Linking the Centriole to the Nucleus in Spermiogenesis"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Cellular Rejuvenation During Meiosis"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"The Missing Link of Surface Mechanics: Protein Caging Triggers Symmetry Breaking"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Planar Cell Polarity and Mechanosensing in Convergent Extension"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Cellular and Tissue Polarity is Controlled by a Conserved Wnt-Ror-Dvl Signalling Cascade in C. Elegans Muscles"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Long Range Mutual Facilitation Complements Local Inhibition to Globally Pattern Rac and Rho During Cell Migration"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Negative Feedback Regulation in Cortical Excitability Requires F-Actin Interaction and Self-Association of RGA-3/4"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Tissue Polarity During Development and Homeostasis
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Intestinal Cartography: Epithelial Dynamics During Pattern Formation in the Developing Mammalian Intestine"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Defining the Role of Dishevelled in Planar Cell Polarity Establishment in the Mammalian Embryonic Epidermis"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Imaging How the Preimplantation Embryo Forms"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Multiple Roles for Inhibitory G Proteins in the Polarization of Auditory and Balance Hair Cells"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Migration and Motility
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"The Evolution and Diversity of Actin-Dependent Cell Migration"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"The Asymmetric Fusogenic Synapse"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Leaders Can’t Lead Without Followers: The Discovery of a Polarity Regulated Rac Activity Pathway in Follower Border Cells"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Cell Polarity and Fate Specification in Echinoderms"
11:15 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Directional Cell Migration: Unveiling the Mechanism of Durotaxis"
11:45 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Receptor Corralling Establishes Front-Rear Polarity During Bleb-Based Migration Under Confinement"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Kiss and Say Goodbye: Emerging Mechanisms of Stem Cell Control"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Combinatorial Role of Signaling Factors in the Maintenance of Drosophila Germline Stem Cell Fate"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"A Pathways for Asymmetric Chromosome Segregation in Response to Stress and Ageing"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Selfish Meiotic Drive Elements Exploit Asymmetry in Female Meiosis"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Mechanisms of Asymmetric Division
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Deciphering Chromosome Segregation in Mammalian Eggs"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Deciphering Asymmetric Cell Fate Determination in C. Elegans Neuroblast Division"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Regulation of Cell Polarity Orientation by Expression Gradients of Wnt Receptors"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Asymmetric Cell Division during Hematopoiesis: Insights from Drosophila"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"State Transitions and Lineage Specification in the Mouse Embryonic Midline"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"The Replicative Helicase CMG is Required for Cell Fate Divergence in C. Elegans"
11:50 am - 11:55 am
Discussion
11:55 am - 12:00 pm
General Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cell Polarity During Development
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Polarized Cell Interactions During Organ Formation in the C. Elegans Embryo"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Polarized Contractility Drives Molecular Translocation to Promote Lumen Initiation and Growth"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Dynamics of Germline Cyst Formation in Mice"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Collective Induction of Oogenesis via Cytoplasmic Streaming in C. Elegans"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Tissue Polarization Planar Cell Polarity
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Think Globally, Act Locally: Control of Axon Guidance by Planar Polarity Cues"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Distinct Modes of PCP-Mediated Cell Intercalation in C. Elegans"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Crawling Under Your Skin: Understanding How Planar Cell Polarity Generates Polarized Cell Movements During Hair Follicle Morphogenesis"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Reversing the Axis of Epidermal Planar Polarity in the Rosette Fancy Mouse"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Working Against the Clock: Leveraging the Biophysics of Polarization to Extend Reproductive Lifespan"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Mechanical Cues Organize Vertebrate Planar Cell Polarity Complexes and Collective Cell Behaviors During Embryonic Wound Repair"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Left-Right Asymmetry in the Positioning of Cell Organelles in Single Myoblasts"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
"Investigating Cell Polarity and Organelle Segregation in Singled-cell Divergent Eukaryotes using Expansion Microscopy"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cues for Cell Polarization and Fate Decisions
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Cytoskeletal Organization Controls Polarity During Patterning of the Leaf Surface"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Spatio-Temporal and Molecular Evolution of the Apical Cell Cortex during Epithelial Polarity Development"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Fat Cadherin Control of Planar Cell Polarity"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"Epithelial Polarization via Myosin-Dependent Cortical Flow"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure