Sequence, Identity, Function and Genome Stability

Centromeres play a crucial role in directing the assembly of kinetochores during mitosis and meiosis, ensuring the proper segregation of chromosomes. Although centromeres serve a universal function, their organization, DNA sequence, and associated proteins vary greatly. Dysfunctional centromeres are known to be associated with diseases, including cancer. As a result, research into centromeres has led to major breakthroughs in our understanding of chromosome segregation, epigenetic mechanisms, cell cycle regulation, chromosome evolution, and disease. Recent advances in imaging, genomics, and gene editing have greatly accelerated progress in the field of centromere biology. The field is at the cusp of major breakthroughs that will impact or understanding of how genomes are inherited and pave the way for potential novel therapies for diseases resulting from misregulation of centromeres.

The 2024 Centromere Biology conference will foster a friendly and vibrant atmosphere, welcoming junior scientists and trainees by selecting talks from submitted abstracts. The primary objective of this conference is to facilitate interaction among a community of scientists interested in centromere biology, allowing them to discover the latest advancements in the field, learn about new technologies and applications, and establish and reinforce connections among scientists at every career stage.