Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Chem-Bio Security for Preparedness Against Future Threats
7:40 pm - 8:20 pm
"Balancing Security and Innovation for Biodefense - A Perspective"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Production of Supply-Limited Natural Product Therapeutics Using Engineered Yeast"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
AI/ML for Chemical and Biological Defense: Emerging Technologies
9:00 am - 9:25 am
"Physiological Indicators of Influenza or COVID-19 Infection"
9:25 am - 9:35 am
Discussion
9:35 am - 10:10 am
"Generation to Implementation: Insights for Secure and Responsible Validation of AI-Driven Biological Predictions in a Complex World"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Evaluating Trustworthy and Credible Machine Learning for Chemical and Biological Defense Applications"
11:20 am - 11:30 am
Discussion
11:30 am - 11:55 am
"Integrating AI into Bioresilience and Response - From Biosurveillance to Outbreak Mitigation"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:25 pm
"Generation to Implementation: Insights for Secure and Responsible Validation of AI-Driven Biological Predictions in a Complex World"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
AI/ML for Chemical and Biological Defense: Global Applications
7:30 pm - 7:50 pm
"Generative Artificial Intelligence for Molecule Design, Reactions and Spectral Analysis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:30 pm
"Biologics Design and Optimization with Generative Unconstrained Intelligent Drug Engineering (GUIDE)"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Challenges and Opportunities of Using AI/ML to Generate Synthetic Data"
9:00 pm - 9:05 pm
Discussion
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Broad Spectrum Methods for Agnostic Chemical and Biological Detection
9:00 am - 9:35 am
"Toward Sequence-Based Agnostic Detection of Biological Threats in Complex Samples"
9:35 am - 9:45 am
Discussion
9:45 am - 10:20 am
"Machine Learning-Enabled Miniature Spectroscopy for Rapid, Reagent-free Biodetection: Shrinking Discovery and Detection Cycles with ProSpectral"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:35 am
"Novel Quantum Sensing Probes for Detection of Trace Chemical and Biological Analytes"
11:35 am - 11:45 am
Discussion
11:45 am - 12:20 pm
"Detecting Biosignatures from Pyrolysis-GCMS Data Using Machine Learning"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Technologies for Diagnostics of Novel Chemical and Biological Agents
7:30 pm - 7:50 pm
"The Challenges and Opportunities of Using Pan-Pathogen Focused Metagenomics to Interrogate Clinical and Environmental Samples for All Natural and Engineered Vertebrate Viruses"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:25 pm
"Metagenomic Sequencing and Host Response Profiling for Diagnosis of Infections"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Beyond Single-Molecule Detection: How Multi-Omics Transforms Diagnostics"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Early Diagnosis: The Key to Successful Management and Treatment of Exposed Personnel"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Biomanufacturing Readiness: From Design to Deployment
9:00 am - 9:35 am
"Launch of the National Biotechnology and Biomanufacturing Initiative: Paving the Way for a New Industrial Base"
9:35 am - 9:45 am
Discussion
9:45 am - 10:20 am
"Science of Scale-Up for Rapid Biological Production of Molecules of Interest"
10:20 am - 10:30 am
Discussion
10:30 am - 11:05 am
Coffee Break
11:05 am - 11:40 am
"Development of Non-Model Microbes for Biomanufacturing Processes"
11:40 am - 11:50 am
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Wearable-Based Advancements for Chem-Bio Threats
7:30 pm - 7:50 pm
"Monitoring How Molecules Move in the Body via Electrochemical Aptamer-Based Sensors"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Can Wearable Technologies be Developed for the Detection of Challenging Targets Such as Biological Macromolecules to Inform on Infectious Disease Outbreaks and Other Biodefense-Relevant Conditions?"
8:20 pm - 8:30 pm
Discussion
8:50 pm - 9:00 pm
Discussion
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Research and Development Challenges Impacting Chem-Bio Security
9:00 am - 9:35 am
9:35 am - 9:45 am
Discussion
9:45 am - 10:15 am
Coffee Break
10:15 am - 10:50 am
"Science, Research & Development, and Policy: Opportunities and Obligations in Chemical & Biological Defense"
10:50 am - 11:00 am
Discussion
11:00 am - 11:35 am
"Defining Hazardous Capabilities of Biological AI Models"
11:35 am - 11:45 am
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Solutions to Counter Emerging Chem-Bio Threats: Vaccines, Therapeutics and Beyond
7:30 pm - 8:00 pm
"Entropy-Based Machine Learning Tools to Detect Epigenetic Biosignatures of Infection"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"The ARPA-H Model: High-Risk Transformative Research on Disease-Agnostic Technologies - Pursuing Better Health Outcomes for All"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Improving the Detection and Response to Biological Threats"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure