Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: The Ever Changing Landscape of Threats to Human Health and Security
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:15 pm
"OP or Not OP, that Is the Question"
8:15 pm - 8:25 pm
Discussion
8:25 pm - 8:50 pm
"How Concerned Should We Be About Gene Drive Technologies?"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Public
Perception of Chemical and Biological Terrorism"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Neural Dysfunction: Mechanisms, Detection, and Countermeasures
9:00 am - 9:15 am
Introduction by Discussion Leader: Introduction and Perspectives on Emerging Issues and Innovative Solutions for Threat Agents Targeting Neural Function
9:15 am - 9:45 am
"Using Novel Enzymes to Protect Against Organophosphorus Toxicity"
9:45 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Intraneuronal Delivery of Single Domain Antibodies for Treatment of Post-Symptomatic Botulism"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:25 am
"Botulinum Toxin - From Biothreat to Biomedicine"
11:25 am - 11:35 am
Discussion
11:35 am - 12:05 pm
"A Tale of Two Threat Agents: OPs and TETS"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Host Interactions and Responses
7:30 pm - 7:45 pm
Introduction by Discussion Leader: Introduction and Perspectives on Host Immunity and
Threat Agents
7:45 pm - 8:10 pm
"Your Own Worst Enemy: How Yersinia pestis Turns the Body Against Itself"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Combining Mechanistic and Global Insights to Identify Critical Interactions Between Pathogen and Host"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Alternative Roles for CRISPR-Cas Systems in Bacterial Pathogenesis"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Host Barrier Function and Dysfunction
9:00 am - 9:15 am
Introduction by Discussion Leader: Overview and Perspectives on the Host Barriers, and How Biological and Chemical Threat Agents Might Affect Barrier Function
9:15 am - 9:45 am
"Inflammatory Mechanisms of Lung Injury Induced by Mustard Vesicants"
9:45 am - 9:55 am
Discussion
9:55 am - 10:20 am
"Rebuilding the Damaged Lung"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"Imaging Mass Spectrometry: Untargeted Molecular Histology at the Host-Pathogen Interface"
11:25 am - 11:35 am
Discussion
11:35 am - 12:05 pm
"Antimicrobial Signaling at the Maternal-Fetal Interface"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:45 pm
Introduction by Discussion Leader: Overview and Perspectives on the the Targeting of Metabolism by Threat Agents
7:45 pm - 8:10 pm
"Metabolic Targets: Modeling and Predictions"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Nuclear Receptors Control Pro-Viral and Antiviral Metabolic Responses to Hepatitis C Virus Infection"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Targeting Viruses Through Cellular Metabolism"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Extended and Emerging Threats to Human Health
and Security
9:00 am - 9:15 am
Introduction by Discussion Leader: Perspectives and Overviews on Extended and Emerging Threats to Human Health and Security
9:15 am - 9:45 am
"CRISPR/Gene Grives: Potential Threats in Plants and Agriculture"
9:45 am - 9:55 am
Discussion
9:55 am - 10:25 am
"From WMDs to CMBs: What Creative Malicious Biologists Could Do, but Haven't"
10:25 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Building Cyberthreat Models for Genomic Security"
11:25 am - 11:35 am
Discussion
11:35 am - 12:05 pm
"Real-Time Genomic Surveillance of Pathogen Evolution and Spread"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Looking Ahead: Young Investigator Presentations / Alternative Approaches
7:30 pm - 7:40 pm
Introduction by Discussion Leader: Perspectives on Emerging Threats and Challenges: A Perspective from the CDC
7:40 pm - 7:55 pm
"The Art of War: Exosomes as Carrier Pigeons of the Cell to Protect from Bacterial Spread During Infection with Yersinia pestis "
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
"Combined Stimulation of a2-Adrenoceptors and GABAA Receptors Abruptly Terminates Soman-Induced Status Epilepticus"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Powerful Science: A Tool of Diplomacy"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Engineering Inhalable Polymeric Prodrugs of Ciprofloxacin for Prophylactic andTherapeutic Treatment of Highly-Lethal Pulmonary Francisella tularensis Infections"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Activating Mitochondrial Quality Control as a Strategy to Combat Mitochondrial Targeted Pathogenic Effectors"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Smart Approaches for Detection, Prevention, and Intervention
9:00 am - 9:15 am
Introduction by Discussion Leader: The Emergence of Smart Solutions to Threat Agents
9:15 am - 9:40 am
"A Platform Technology Based on a Nanocomplex that Actively Crosses the Blood-Brain Barrier and Its Use in Medical Countermeasures Against Both Chemical and Biological Threat Agents"
9:40 am - 9:50 am
Discussion
9:50 am - 10:20 am
"Interrogation of In Vivo Modes of Action of Positron-Labeled Organophosphates and Antidotes with Dynamic PET Imaging"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"You Catch More Flies (and Mosquitoes) with Honey - A New Approach to Automating Surveillance for Arboviruses"
11:25 am - 11:35 am
Discussion
11:35 am - 12:05 pm
"Nanolayered Delivery from Trauma: Delivery Solutions for Field Care Medicine"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Working at the Periphery: Bioengineering-Inspired Solutions for Counteracting Biological and Chemical Threats
7:30 pm - 7:45 pm
Introduction by Discussion Leader: Perspectives and Overview of the Capacity of Bioengineering to Meet the Challenges and Opportunities Associated with Existing and Emerging Threats
7:45 pm - 8:10 pm
"Plant Virus-Based Nanotechnologies"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"High Performance Lateral Flow Assays as First Line of Defense Against Bioagents"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure