| SATURDAY |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Synthetic Biology in Chemical and Biological Defense Research |
| 3:45 pm - 4:15 pm | Andrew Ellington (University of Texas at Austin)
"White Hats and Black Hats: The Ethical Responsibilities of Biodefense" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Novel Avenues in Chemical and Biological Defense Research |
| Discussion Leader: David Lowe (University of Virginia) |
| 7:30 pm - 7:50 pm | Erin McAlister (Defense Science and Technology Laboratory, UK)
"Lethal genes: a new method for studying essentiality" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Stephanie Suzuki (University of Washington)
"Expression, purification, and characterization of human PON1 mutants in an Escherichia coli system" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Patrick McNutt (Medical Research Institute of Chemical Defense, USA)
"Mouse embryonic stem-cell derived neurons are a novel, highly sensitive tissue culture platform for neurotoxin research" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Angela Courtney (University of California, Davis)
"The use of synthetic particles to replicate the body's innate immune system functions" |
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Host Defense and Pathogenesis / Toxicity |
| Discussion Leader: Ian Gut (University of Illinois) |
| 9:00 am - 9:20 am | Tamilselvam Batcha (University of Illinois)
"The great escape: remodeling of bacillus-containing vacuoles by a germination-dependent mechanism to promote the release of intracellular Bacillus anthracis from immune cells" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Brittany Mortensen (The University of North Carolina)
"The role of RipA in Francisella tularensis virulence and immune evasion" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Stephanie Richards (Defense Science and Technology Laboratory, UK)
"The phage-shock protein response as a broad spectrum therapeutic target" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Judit Marsillach-Lopez (University of Washington)
"Isolation and characterization of human biomarkers following exposure to organophosphates" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Toxins in Biological Defense Research |
| Discussion Leader: Stephanie Rogers (Oklahoma State University) |
| 1:30 pm - 1:50 pm | Laura Patrussi (University of Siena, Italy)
"A novel mechanism of immunosuppression by adenylate cyclase toxins" |
| 1:50 pm - 2:00 pm | Discussion |
| 2:00 pm - 2:20 pm | Nareen Abboud (Albert Einstein College of Medicine, USA)
"A requirement for FcγR in antibody-mediated bacterial toxin neutralization" |
| 2:20 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
