Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Bridging the Gap Between Fundamental and Applied Peptide Science
7:40 pm - 8:20 pm
"Bridging the Gap Between Fundamental and Applied Science in DNA Recognition by Py-Im Polyamides"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Engineering New Peptide Ligases"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Stabilized Peptide Therapeutics
9:00 am - 9:25 am
"Challenges and Emerging Approaches in Peptide Drug Discovery"
9:25 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Orally Stable Peptides - Fact or Fiction? Or Discovery and Development of Orally Stable Peptides for Gastro-Intestinal (GI) Diseases"
10:05 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Exploring the Signaling of D-Amino Acid-Containing Neuropeptides"
10:35 am - 10:40 am
Discussion
10:40 am - 11:10 am
Coffee Break
11:10 am - 11:35 am
" Mimicking Protein-Protein Interactions Through Peptide-Peptide Interactions: CXCR4 and HIV-1 gp120"
11:35 am - 11:50 am
Discussion
11:50 am - 12:15 pm
"The Optide Platform: Designing, Engineering, and Evolving Peptide Drug Candidates"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Advances in Peptide and Protein Synthesis
7:30 pm - 7:55 pm
"Automated Flow Peptide Synthesis: Toward Amide Bonds at Nature’s Pace"
7:55 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
"Massively Parallel Synthesis and Screening of Linear Peptides and Macrocycles Using Peptide Microarrays"
8:35 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Ligases: Specific Peptide Staplers"
9:15 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:25 am
" Peptide Design and Assembly: From Fundamental Principles to Real-Life Applications"
9:25 am - 9:40 am
Discussion
9:40 am - 10:05 am
" Structure-Based Design of Broad Flavivirus Immunogens"
10:05 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Shape-Specific Nanostructured Protein Mimics from De Novo Designed Chimeric Peptides"
10:35 am - 10:40 am
Discussion
10:40 am - 11:10 am
Coffee Break
11:10 am - 11:35 am
"Design and Synthesis of Highly Fluorinated Biopolymers as 19F MRI Contrast Agents"
11:35 am - 11:50 am
Discussion
11:50 am - 12:15 pm
"Massively Parallel Investigation of De Novo Miniprotein Folding and Binding"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Amyloids and Peptide Self-Assembly
7:30 pm - 7:55 pm
"Conformational Polymorphisms of the Amyloid Aβ Peptide in Alzheimer’s Disease"
7:55 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
"Understanding the Cellular Membrane Disruption Induced by Early-Stage Aggregation of Beta-Amyloid Peptides"
8:35 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Chirality, Alzheimer's Disease and Amyloid Beta"
9:15 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:25 am
"Engineering Armadillo Repeat Proteins as Modular Peptide Binders"
9:25 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Exploring the Landscape of Bcl-2 Family Binding Peptides"
10:05 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Accurate Computational Design of Heterochiral Constrained Peptides"
10:35 am - 10:40 am
Discussion
10:40 am - 11:10 am
Coffee Break
11:10 am - 11:35 am
"Engineering Complimentary Peptide and Antibody Attributes for Efficient Hybridization"
11:35 am - 11:50 am
Discussion
11:50 am - 12:15 pm
"Molecular Basis of Protein-Carbohydrate Interactions"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Cell Penetration and Drug Delivery
7:30 pm - 7:55 pm
" Exploring Macrocyclic Peptide Cell Permeability: Screening Tools and Design Rules"
7:55 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
" Molecular Engineering of Helical Peptides: Designing Intracellular Therapeutics"
8:35 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Peptide-Based Tools to Study Cell Signaling in Bacteria"
9:15 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Next-Generation Peptide Therapeutics
9:00 am - 9:15 am
"Stapled Peptide Inhibitors of the Estrogen Receptor/Coactivator Interaction"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Cell Penetration Profiling Using the Chloroalkane Penetration Assay"
9:35 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Targeting Peptides for Nanomedicine"
10:05 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Rational Development of Bicyclic Peptides Targeting the Grb7 Cancer Target"
10:35 am - 10:40 am
Discussion
10:40 am - 11:10 am
Coffee Break
11:10 am - 11:35 am
"Reductionist Vaccine Design for HIV"
11:35 am - 11:50 am
Discussion
11:50 am - 12:15 pm
"Plants as Biofactories for Producing Peptide-Based Pharmaceuticals"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:55 pm
"Peptide-Based Materials for Regenerative Medicine Applications"
7:55 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
"Peptide and Protein Nanomaterials: The Design Challenge"
8:35 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Racemic Hydrogels from Mirror Image Peptides: Predictions from Pauling and Corey"
9:15 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure