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Chemotactic Cytokines (GRS)

Gordon Research Seminar

Chemokine Control of Immunity - From Homeostasis to Disease

June 2 - 3, 2018

Chairs

and

Jordan Hotel at Sunday River

27 Grand Circle

Newry, Maine, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Chemotactic Cytokines is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

Through their control of cell migration, chemotactic cytokines (chemokines) control the complex processes of immune function. This meeting will focus on emerging concepts in chemokine biology including their structure and function, as well as their roles in homeostasis and development, immune activation, cancer, and chronic inflammation.

Related Meeting

This GRS will be held in conjunction with the "Chemotactic Cytokines" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Chemokines: Insights from Structural and Functional Data Discussion Leader:
3:45 pm - 3:55 pm	"Nanoluciferase Complementation-Based Assay to Monitor β-Arrestin Recruitment to Chemokine Receptors"
3:55 pm - 4:00 pm	Discussion
4:00 pm - 4:10 pm	"Structural Studies into Autoinhibition by CCL21"
4:10 pm - 4:15 pm	Discussion
4:15 pm - 4:25 pm	"Atypical Ligand Binding and Activation Modes of ACKR3"
4:25 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Chemokines in Homeostasis and Development Discussion Leader:
7:30 pm - 7:40 pm	"Engineering an Orthogonal Chemokine:GPCR System Using Rosetta"
7:40 pm - 7:45 pm	Discussion
7:45 pm - 7:55 pm	"Binding and Activation Variation Within the CCR1-2-5 Axis"
7:55 pm - 8:00 pm	Discussion
8:00 pm - 8:10 pm	"A Molecular 'Clamp' Regulates Sdf1a and Sdf1a-Guided Cell Migration"
8:10 pm - 8:15 pm	Discussion
8:15 pm - 8:25 pm	"CXCL12/SDF-1 Modulates the Rheological Properties of the Nucleus of Mouse Neutrophils"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:40 pm	"The Role of Heterotrimeric G Proteins in Homing and Migration of Lymph Derived T Cells"
8:40 pm - 8:45 pm	Discussion
8:45 pm - 8:55 pm	"Complement C5a Receptor Regulates CXCR2-Mediated Neutrophil Adhesion"
8:55 pm - 9:00 pm	Discussion
9:00 pm - 9:10 pm	"COOH-Terminal SAA1 Peptides Fail to Induce Chemokines but Synergize with CXCL8 and CCL3 to Recruit Leukocytes via FPR2"
9:10 pm - 9:15 pm	Discussion
9:15 pm - 9:25 pm	"Homing of Activated, Lymph-Derived T Cells Involves a Mechanical 3D Sieve Barrier of the Subcapsular Sinus and Chemokine Receptors but Is Independent of Integrins and Selectins"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Chemokine Control of Immune Activation and Disease Discussion Leaders: and
9:00 am - 9:10 am	"Targeting Lymph Node Niches to Enhance Type 1 Immune Responses to Immunization"
9:10 am - 9:15 am	Discussion
9:15 am - 9:25 am	"Age-Related Systemic Inflammation Supports Aberrant Neutrophil Transendothelial Migration"
9:25 am - 9:30 am	Discussion
9:30 am - 9:40 am	"Identification of CXCL14-Responsive Cells in Healthy Peripheral Tissues"
9:40 am - 9:45 am	Discussion
9:45 am - 9:55 am	"The Role of Dendritic Cells in the Dissemination of Mosquito-Transmitted Alphaviruses"
9:55 am - 10:00 am	Discussion
10:00 am - 10:10 am	"Dectin-2-Induced CCL2 Production in Cardiac Macrophages Ignites Vascular Inflammation in a Murine Model of Kawasaki Disease"
10:10 am - 10:15 am	Discussion
10:15 am - 10:25 am	"CXCL14 Suppresses the Aggressive Phenotype in Triple Negative Breast Cancer (TNBC) Through CXCR4"
10:25 am - 10:30 am	Discussion
10:30 am - 10:40 am	"Drug-Induced Senescence Promotes Anti-Tumor Immunity via the Induction of CCL5"
10:40 am - 10:45 am	Discussion
10:45 am - 10:55 am	"Aeroallergen-Induced Central Memory CD4+ T Cells Induce Allergic Airway Inflammation Independently of Lung-Resident Memory"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Career Pathways Discussion Leaders: and
1:30 pm - 2:30 pm	Panel Discussion Career Pathways
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

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Conference History Chemotactic Cytokines

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Chemotactic Cytokines

June 7 - 12, 2026

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