Sunday July 16
7:30 p.m.-9:30 p.m. | Session 1. Histone Modification |
Chair : D. Allis
- D. Allis - Mitotic histone phosphorylation: Is there a 'histone code'
- S. Berger - Functional interaction between histone phosphorylation and acetylation in gene activation
- L. Mahadevan - Short talk (10') H1 Phosphorylation
- M. Gorovsky - Short talk (10') H1 Phosphorylation / acetylation
- R. Dutnall - Short talk (10') Insights into histone acetylation from the structures of two HATs
- M. Grunstein - Multiple histone deacetylase functions in yeast
Monday July 17
9:30 a.m.-12:30 a.m | Session 2. Heritable States |
Chair : S. Tilghman
- J. Lee - Regulation of X-inactivation by Tsix
- S. Tilghman - Mechanisms of gene silencing in imprinting
- A. Wolffe - Integrating DNA methylation with targeted gene control in chromatin
- R. Kelley - Targeting dosage compensation to the X chromosome with roX RNAs
- R. Paro - Switching chromosomal memory elements
- S. Grewal - Short talk (10') - Imprinting functions of a chromodomain protein Swi6 in fission yeast
- E. Selker - Short talk (10') - Role of histone acetylation and DNA methylation in epigenetic regulation in Neurospora
| 7:30 p.m.-9:30 p.m. | Session 3. Genome Stability |
Chair : G. Almouzni
- G. Almouzni - Chromatin assembly at the cross-roads of DNA repair and replication
- P. Kaufman - Nucleosome assembly proteins in budding yeast
- B. Stillman - Linking DNA replication to epigenetic inheritance
- F. Ishikawa - Short talk (10') MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase
- J. Haber - Regulation of a locus control in yeast that controls recombination along a chromosome arm
- C. Fox - Short talk (10') Conserved forkhead genes, FKH1 and FKH2, regulate cell-cycle progression and differentiation in S. cerevisiae
Tuesday July 18
9:00 a.m.-12:30 a.m | Session 4. Heterochromatin |
Chair : S. Henikoff
- M. Smith - How many histones does it take to change an octamer
- S. Henikoff - Centromere replication in Drosophila
- G. Karpen - Centromere identity and function in Drosophila
- R. Sternglanz - Studies on the mechanism of the SIR2 family of NAD-dependent protein deacetylases
- D. Shore - Regulation of silencing in yeast: the role of Sir2
- D. Moazed - Sir2, NAD, and transcriptional silencing
- S. Imai - Short talk (10') The mouse Sir2 homolog, mSir2alpha
| 7:30 p.m.-9:30 p.m. | Session 5. Chromosome organization and condensation |
Chair : U. Laemmli
- U. Laemmli - Specific gain and loss of function phenotypes induced by Satellite-specific DNA-binding drugs fed to Drosophila melanogaster
- T. Hirano - Condensin, cohesion and chromosome dynamics
- B. Meyer - Dosage compensation in C. elegans
- L. Wallrath - Conserved mechanisms of HP1-mediated silencing
- Y. Hiraoka - Short talk (10') A centromere-associated protein implicated in nuclear positioning of centromeres
Wednesday July 19
9:00 a.m.-12:30 a.m. | Session 6. Chromatin domains |
Chair : G. Felsenfeld
- G. Felsenfeld - Chromatin boundaries
- V. Corces - Chromatin insulators and nuclear organization
- R. Kamakaka - The establishment and termination of silencing at HMR
- V. Pirrotta - Recruitment of Polycomb silencing complexes
- J. Broach - Silencing and switching of the mating type loci in yeast
- M. Gartenberg - Short talk (10') - Yeast heterochromatin
- D. Duboule - Organizing domains of regulation within Hox clusters
| 7:30 p.m.-9:30 p.m. | Session 7. Nuclear order |
Chair : J. Sedat
- F. Grosveld - Chromatin, cell cycle and beta-globin gene transcription
- A. Fisher - Nuclear organisation and gene silencing in commitment
- J. Sedat - Insights into anaphase chromosome structure using EM tomography
- A. Belmont - Large-scale chromatin structure and dynamics
- J. Pehrson - Short talk (10') H2A macro variant
Thursday July 20
9:00 a.m.-12:30 a.m | Session 8. Chromatin activation and transcription |
Chair : R. Kingston
- R. Kingston - Chromatin remodeling by SWI/SNF and inhibition by Polycomb repressive complex 1
- L. Pillus - Regulating chromatin through histone acetylation
- J. Hansen - Transcriptional regulation from the perspective of the nucleosomal array
- R. Young - Global gene expression patterns
- C. Peterson - Global role for chromatin remodeling enzymes in mitotic gene expression
- J. Kadonaga - Studies of the regulation of transcription by RNA polymerase II
- R. Festenstein - Short talk (10') Triplet repeats can mediate "Position Independent Variegation"
- S. Roth - Short talk (10') Antagonism of Ssn6-Tup1 repression by histone acetylation
| 7:30 p.m.-9:30 p.m. | Session 9 : Chromatin Remodeling |
Chair : C. Wu
- J. Workman - Transcription regulation by yeast histone acetyltransferase complexes
- P. Becker - Molecular definition of CHRAC, a nucleosome mobilizing ATPase
- C. Wu - Role of ATP-dependent chromatin remodeling in transcription and DNA processing
- M. Cole - Nuclear cofactors implicate chromatin remodeling in Myc-mediated oncogenesis
- T. Tsukiyama - The in vivo functions of ISW2 chromatin remodeling complex
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