Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Dissecting the 3D Genome’s Structure-Function Relationship in the Mammalian Brain
Discussion Leader: Hayden Saunders (UCSF, United States)
3:45 pm - 4:25 pm
Jennifer Phillips-Cremins (UPenn, United States)
"Dissecting the 3D Genome’s Structure-Function Relationship in the Mammalian Brain"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Exploring the Architectural Dynamics of Chromatin
Discussion Leader: Geeta Narlikar (University of California, San Francisco, United States)
7:30 pm - 7:40 pm
Keerthivasan Raanin Chandradoss (University of Pennsylvania, United States)
"Elucidating BREACHes (Beacons of Repeat Expansion Anchored by Contacting Heterochromatin) in Fragile X Syndrome"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Michael Arowosegbe (The University of Arizona, United States)
"The Roles of Lysine Deacetylase 1 Complexes in the Positive Regulation of Transcription"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Oscar Arroyo (University of North Carolina - Chapel Hill, United States)
"Selective Depletion of Histone Transcripts to Interrogate Histone Residue Function"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Rochelle Yap (University of Georgia, United States)
"Rtt109 is an Acetyltransferase Required for Polycomb Repression Complex 2 Mediated Gene Silencing in Neurospora Crassa"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Jacques Serizay (Institut Pasteur, France)
"Emergence of Vertebrate Heterochromatin Features in Foreign D Integrated into a Eukaryotic Nucleus"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Sweta Sikder (National Cancer Institute, United States)
"Deciphering Chromatin Regulation and Centromere Dynamics During Aging"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Joji Marie Teves (MIT, United States)
"Profiling the Transitional State during High Efficiency Reprogramming"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Regulating the Genome: Unraveling Chromatin Transformations
Discussion Leaders: Andreas Ladurner (Ludwig-Maximilians-University of Munich (LMU Munich), Germany) and Kaustubh Wagh (National Cancer Institute, National Institutes of Health, USA, United States)
9:00 am - 9:10 am
Pawel Trzaskoma (NIAMS NIH, United States)
"Cohesin, BRD4 and Mediator Have Distinct Roles in Regulating Transcriptome-wide Bursting and Gene Network"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Biswajit Ghosh (Freie Universität Berlin, Germany)
"Multiple Classes of Epigenetic Regulators Interact to Regulate Nuclear Morphology and Chromatin Organization in Arabidopsis "
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Yuya Zhao (New York University, United States)
"Investigating the Effects of R Polymerase II on D Loop Extrusion in Caenorhabditis Elegans "
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Gerardo Mirizio (Cincinnati Children's Hospital Medical Center, United States)
"Cooperation of Pioneer TFs and PRDM1 Enhances Polycomb Repressive Domains Formation to Control Cell Fate"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Sedona Murphy (Yale University , United States)
"Decoupling Space and Time in Chromatin Regulation of Hox Gene Developmental Patterning"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Rachel Hoffman (Nationwide Children's Hospital, United States)
"A Chromatin-Based Goldilocks Principle Influences Cell Cycle Regulation in Rhabdomyosarcoma"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Ryan Boileau (Duke University, United States)
"A Synthetic Pioneer Transcription Factor System Identifies MLL3/4 as Cofactors of GRHL2"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Shuya Wang (University of California, Los Angeles, United States)
"MBD2 Couples DNA Methylation to Transposable Element Silencing During Male Gametogenesis"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Mentoring for Diversity: Navigating Inclusive Mentor-Mentee Relationships from Both Sides of the Spectrum
Discussion Leader: Clarice Hong (Massachusetts Institute of Technology, United States)
1:30 pm - 2:30 pm
Panel Discussion
Perspectives on Diverse Mentorship: From Both Sides
Seychelle Vos (MIT, United States)
Lu Sun (EpiCypher Inc, United States)
Shiv Grewal (National Cancer Institute, NIH, United States)
Asifa Akhtar (Max Planck Institute of Immunobiology and Epigenetics, Germany)
Jennifer Phillips-Cremins (UPenn, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes