Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Single Molecules to Translational Intervention
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:15 pm
"Sequence-Dependent Insights into Collagen’s Structure and Mechanics"
8:15 pm - 8:25 pm
Discussion
8:25 pm - 8:50 pm
"Developing Genetic Precision Therapies for Type VI Collagenopathies"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Organelle Level Adaptations to Accommodate Collagen Biosynthesis
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Critical Role of the Unfolded Protein Response (UPR) in Collagen Biogenesis and Liver Fibrosis"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
Short Talk Selected from Poster Abstracts
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Understanding the Role of Npropeptide in Collagen-I Homeostasis"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Collagen Post Translational Modifications at The Interface of Extracellular Matrix (ECM) Remodelling and Cardiac Fibrosis"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
Short Talk Selected from Poster Abstracts
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Shedding New Light on Procollagen Proteolytic Maturation"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
Short Talk Selected from Poster Abstracts
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hour™ is open to all conference participants.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Molecular Adaptations to Accommodate Collagen Biosynthesis
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Mechanisms of Procollagen Folding and Assembly"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"ER Exit Site Machinery for Enabling the Secretion of Collagen"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
Short Talk Selected from Poster Abstracts
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"TANGO1 Builds a Secretory Route for Collagen"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Inherited Genetic Collagen Disorders
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Targeting Collagen I Intracellular Accumulation"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
Short Talk Selected from Poster Abstracts
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Type V Collagen in Man, Mouse and Zebrafish"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Impact of Glomerular Basement Membrane Defects in Alport Syndrome"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
Short Talk Selected from Poster Abstracts
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Collagen Quality and Quantity in Non-Classical Forms of Osteogenesis Imperfecta"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
Short Talk Selected from Poster Abstracts
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Triple Helix: Collagens’ Common Thread
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Collagen VI Microfibril Structure Reveals Mechanism for Molecular Assembly and Consequences of Inherited Pathogenic Mutations"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
Short Talk Selected from Poster Abstracts
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Decoding How Collagens Fold and Remain Folded"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Matrix Remodeling in Steatohepatitis"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
Short Talk Selected from Poster Abstracts
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Understanding Synovial Fibrosis during Osteoarthritis through Cellular and Transcriptomic Profiling"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"The Collagen Receptor DDR1 Regulates Mitochondrial Function Following Kidney Injury"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
Short Talk Selected from Poster Abstracts
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Matrix Stiffness and Hormone-Dependent Breast Cancer Progression"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
Short Talk Selected from Poster Abstracts
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Chemistry and Biophysics: Single Molecules to Biomaterials
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Biomaterials Design for Studying Extracellular Matrix Mechanobiology in Aging"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"A Swiss Army Knife: Collagen Produces, Scavenges and Relays Free Radicals"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
Short Talk Selected from Poster Abstracts
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Collagen Fibril Structure and Biomineralization"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Advanced Imaging and Model Organisms
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Reversible Myocardial Fibrosis Lacks Pyridinoline Cross-Links Despite Extensive Collagen Linking"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
Short Talk Selected from Poster Abstracts
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Dynamic Regulation of ECM Stability During Drosophila Development"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"A Complete Collagen IV Fluorophore Toolkit Reveals New Insights into Trimer Diversity, Turnover, and Aging"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
Short Talk Selected from Poster Abstracts
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"From Sequence to Structure: Understanding Collagen's Functional Landscape"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
Short Talk Selected from Poster Abstracts
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Big Data and Computational Approaches
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Risk Mapping: Quantifying the Effects of Type IV Collagen Genetic Variation Using Population Genomics"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"MatriGO: A Comprehensive Framework of Extracellular Matrix Gene Ontologies and its Application to Omic Studies"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
Short Talk Selected from Poster Abstracts
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Novel Proteomic Approaches for Identifying Organ-Conserved Extracellular Matrix Damage in Ageing and Disease"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure