Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Combinatorial Methods in NMR Spectroscopy
3:15 pm - 3:55 pm
"Evolution of Catalysis and Regulation over 3.5 Billion Years: Exploitation for Novel Cancer Drugs"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Complementary Approaches: Advancements of MD Simulations to Bridge Experimental Techniques
5:30 pm - 5:50 pm
"Functional Plasma Membrane Activation: Ions Take Charge"
5:50 pm - 6:00 pm
Discussion
6:00 pm - 6:20 pm
"Parsing Protein Dynamics of Methyl Side-Chain Residues Using MD Simulation"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Integrative Membrane Protein Structure Modeling from Sparse Paramagnetic NMR Data and Small-Angle Scattering Data"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Understanding the Role of Pathogenic and Potective Mutations on the Native State Stability and Dynamics of Mouse Prion Protein (moPrP)"
7:20 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Using NMR to Investigate Protein Ensembles and Their Interactions
9:00 am - 9:20 am
"Probing Protein Dynamics Using Variable Temperature NMR Relaxation"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"How Do Intrinsically Disordered Regions Achieve Specific Interactions with Partner Proteins and DNA?"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Coupling Between the Emergent Phase Behavior of a Disordered Low Complexity Region and Its Single Chain Properties"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
"Understanding the Structural Basis of Recognition Between Plasmodium falciparum and Human Sumoylation Machinery"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Academic Tips and Tricks
1:30 pm - 2:20 pm
"Uncovering the Marvels of Protein Conformational Heterogeneity Along Roads Less Traveled"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes