Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Latest Updates in Skin Biology
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:20 pm
"Exploring the Transition from Stem Cell to Differentiated Cell in Human Epidermis"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:05 pm
"Stem Cell-Centric Mechanisms of Hair Follicle Aging"
9:05 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Ocular Surface and Lacrimal Gland
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Development of Causative Treatment Strategies for Lacrimal Gland Insufficiency by Tissue Engineering and Cell Therapy"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
"PPAR Signaling Regulates Meibocyte Differentiation of Cultured Human Meibomian Gland Epithelial Cells (hMGEC)"
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Effect of Intermittent Shear Stress on Corneal Epithelial Cells Using an In Vitro Flow Culture Model"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Neuronal Control of Lacrimal Gland Development and Regeneration"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
"Glycosylation Pathways in Ocular Surface Disease"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Pea3 Transcription Factors Determine the Lacrimal Gland Cell Fate"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Microbiology and Infectious Disease
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"The Host Immune Response to Corneal Infection: The Battle Between the Bug and the Body"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"The Continuing Challenge of Antibiotic Resistance in Corneal Infection"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Pseudomonas : Pathogenesis, Proteomics and Licorice"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
"Development of Hypoxia and Prevalence of Glycolytic Metabolism in Herpes Stromal Keratitis Lesions"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Stromal Development, Disease and Therapy
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Developmental Dynamics of the Corneal Extracellular Matrix"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Combination Gene Therapy for Treating Corneal Scarring and Angiogenesis"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
"Periocular Neural Crest Differentiation into Corneal Cells Is Dependent on Cues from the Ocular Environment"
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Corneal Myofibroblasts: Evidence of Differentiation from Adult Schwann Cells"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Small Leucine-Rich Repeat Proteoglycans of the ECM Regulate Innate and Adaptive Immunity"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
"Limbal Mesenchymal/Stromal Stem Cells: Role in Corneal Wound Healing and Regeneration"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Fibrocytes Migrate to the Cornea and Differentiate into Myofibroblasts During the Wound Healing Response to Injury"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Translational Research: In Search of New Therapies
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Corneal Stem Cells Mimicking In Vitro Niches"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Translational Research on Corneal Endothelial Regeneration"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"The Hair Follicle at the Center of Skin Regeneration"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
"Co-Ordinated Generation of Multiple Ocular-Like Cell Lineages and Fabrication of Functional Corneal Epithelial Cell Sheets from Human iPS Cells"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Innate and Acquired Immunity in Corneal Pathophysiology
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Loss and Restoration of Immune Regulatory Function in Corneal Inflammation"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Stem Cell Therapies for Efficient Treatment of Immune-Mediated Diseases of the Eye"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
"SLURP1 Stabilizes HUVEC Barrier Function, Suppressing dHL-60 Neutrophil Binding, Transmigration and Chemotaxis"
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Regulation of CD11c Positive Cells by TLR3 in the Cornea"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Contribution of Mast Cells in Non-Allergic Corneal Inflammation"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
"The Role(s) for CD4+T Cell Subsets in Conjunctival Inflammation"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Virulence Determinants and Host Response During Pseudomonas aeruginosa Interaction with the Ocular Surface In Vitro and In Vivo "
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Disease Models for Therapeutic Interventional Studies
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:05 pm
"Modeling Human Diseases with iPS Cells and Genetically Modified Non-Human Primates"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Strategies of Gene and Cell Therapy of Corneal Diseases Using Mouse Model"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Role of the Microbiome in the Pathogenesis of Sjogren Syndrome"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"In Vitro Modeling of Aniridia-Related Pax6 Haploinsufficiency by the Use of CRISPR/Cas9 on Limbal Epithelial Cells"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Tissue Homeostasis and Wound Healing
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"DNA Damage in the Pathogenesis of Fuchs Endothelial Corneal Dystrophy"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Attenuating Age-Related Intraepithelial Corneal Nerve Loss"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
"Kruppel-Like Factor 4 (KLF4) Regulates Corneal Epithelial Stratification by Controlling Cell Polarity and Plane of Cell Division"
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Shp2 Protein Tyrosine Phosphatase Regulates Corneal Epithelial Stratification and Innervation"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
"Dissecting the Functional Role of Melanocytes in the Human Limbal Niche"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
"Molecular Regulation of Limbal Stem Cells"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Inhibition of Traumatic and Genetic Models of Corneal Vascularization with Overexpression of FOXC1"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Genetic and Hormonal Regulation of Corneal Disease
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Elucidating the Molecular Basis of Posterior Polymorphous Corneal Dystrophy: Effects of Decreased ZEB1 Expression on Corneal Endothelial Cell Transcriptome and Function"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Advances in the Genetic Classification of Corneal Dystrophies"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Current Status of the Role of Hormones in Keratoconus"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
"Aberrant DNA Methylation of miRNAs in Fuchs Endothelial Corneal Dystrophy"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure