Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Data Acquisition and Analysis
Discussion Leader: Mehrnoosh Saghizadeh (Cedars-Sinai Medical Center, United States)
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:25 pm
Michael Chiang (National Institutes of Health, United States)
"Data Science and the Future of Clinical Care and Vision Research"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
Randy Schekman (University of California, Berkeley, United States)
"Extracellular Vesicles and Cellular Homeostasis"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Cornea and Ocular Surface Wound Repair
Discussion Leader: Vivian Lee (University of Pennsylvania, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Audrey Bernstein (SUNY Upstate Medical University, United States)
"Corneal Wound Healing and What We Can Learn From the Reindeer Story"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Shigeto Shimmura (Fujita Medical Innovation Center Tokyo, Japan)
"Eat or Be Eaten: A New Role for Mesenchymal Stromal and Stem Cells in Disease and Repair"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
Shizuya Saika (Wakayama Medical University, Japan)
"Tenascin X Function in Corneal Tissue Morphogenesis and Response to Injury"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
Shigeru Kinoshita (Kyoto Prefectural University of Medicine, Japan)
"Biological Characteristics of Cultured Human Corneal Endothelial Cells for Cell Injection Therapy"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Kathryn Colby (NYU Grossman School of Medicine, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Genomics and Gene Regulation
Discussion Leader: Shivalingappa Swamynathan (University of South Florida, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
Ruby Shalom-Feuerstein (Israel Institute of Technology, Israel)
"Eyes Open on Limbal Epithelial Stem Cell Populations and Their Regeneration"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Jakub Famulski (University of Kentucky, United States)
"Tracking Anterior Segment Development in Zebrafish using Transcriptomics and Live Cell Imaging"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
Han Peng (Northwestern University, United States)
"Limbal Epithelial Stem Cell Homeostasis Is Preserved, in Part, via the Novel IFITM1/OVO1 Regulatory Pathway"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cellular Interactions, the Extracellular Matrix, and Morphogenesis
Discussion Leader: Brenda Bohnsack (Ann & Robert H. Lurie Children's Hospital of Chicago, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Mary Ann Stepp (George Washington University School of Medicine and Health Sciences, United States)
"Mitochondrial Transfer Between Corneal Epithelial Cells and Sensory Axons In Vitro and In Vivo"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Carlo Iomini (Johns Hopkins University, United States)
"Decoding Primary Cilia-Mediated Signaling in Anterior Segment Development and Diseases"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
Matilda Chan (University of California, San Francisco, United States)
"Matrix Metalloproteinases and Corneal Wound Repair: Roles Beyond Remodeling"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
Chia-Yang Liu (University of Cincinnati, United States)
"Pathobiology of Corneal Ectasia in Genetic Mouse Models"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Mechanisms of Ocular Surface Disease and Disorders
Discussion Leader: Fiona Stapleton (UNSW Sydney, Australia)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
Ula Jurkunas (Schepens Eye Research Institute, United States)
"Corneal Epithelial Cell Therapy: Where Are We Heading Next?"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Vivien Coulson-Thomas (University of Houston, United States)
"The Role of Hyaluronan in Age-Related Meibomian Gland Dysfunction"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
Penny Asbell (University of Memphis, United States)
"Tear Analysis: Minimally Invasive Metrics for Ocular Surface Disease"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Stem Cells of the Ocular Surface
Discussion Leader: Nick Di Girolamo (University of New South Wales, Australia)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
James Jester (University of California, Irvine, United States)
"Meibocyte Differentiation and the Role of PPAR-Gamma"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Yuzuru Sasamoto (Boston University Chobanian , United States)
"Understanding Ocular Surface Epithelial Cell Differentiation with Newly Identified Markers"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
Ursula Schlötzer-Schrehardt (University of Erlangen–Nuremberg, Germany)
"Limbal Niche Cells-Derived Exosomes and Melanosomes: Potential Tools for Stem Cell-Based Ocular Surface Reconstruction"
11:25 am - 11:35 am
Discussion
11:35 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:10 pm
Shukti Chakravarti (NYU Langone Health, United States)
"Can We Develop Human Corneal Organoids for Cell Therapies and a Pre-Animal Model System?"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Inflammation and Regeneration of the Ocular Surface
Discussion Leader: Dimitrios Karamichos (University of North Texas Health Science Center, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
Lu Chen (University of California, Berkeley, United States)
"Corneal Lymphangiogenesis and Beyond"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Ali Djalilian (University of Illinois at Chicago, United States)
"Early Phase Clinical Studies on Mesenchymal Stromal Cells on the Cornea and Ocular Surface"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
Nicole Carnt (University of New South Wales, Sydney, Australia)
"Profiling the Human Response to Corneal Infection"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Sickness and Health of the Cornea and Ocular Surface
Discussion Leader: Natalie Afshari (University of California, San Diego, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
Rajiv Mohan (University of Missouri, United States)
"Scarless Corneal Repair and Transparency Restoration in Rabbits via Targeted Sirt1 Gene Transfer"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
Pablo Argueso (Tufts University, United States)
"The Influence of the Glycocalyx on Limbal Epithelial Cell Biology"
9:55 am - 10:05 am
Discussion
10:05 am - 10:15 am
Short Talk Selected from Poster Abstracts
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:25 am
Edgar Espana (University of South Florida, United States)
"Manipulating Scar Formation After Injury"
11:25 am - 11:35 am
Discussion
11:35 am - 11:55 am
Sarah Knox (University of California, San Francisco, United States)
"Limbal and Keratocyte Dynamics in the Healthy and Injured Cornea"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Translation of Ocular Surface Research into Novel Therapies
Discussion Leader: Alexander Ljubimov (Cedars-Sinai Medical Center, United States)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
Rachel Wozniak (University of Rochester, United States)
"Ophthalmic Antimicrobial Drug Discovery and Development: Bench to Bedside"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
Fushin Yu (Wayne State University, United States)
"Targeting Programmed Cell Death Pathways for Treating Corneal Injury and Diseases"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
Short Talk Selected from Poster Abstracts
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
Sayan Basu (L V Prasad Eye Institute, India)
"Corneal Stromal Regeneration: Stem Cells, Hydrogels, and 3D Bioprinting"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure