Crystals
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Discussion leader: Wayne Anderson
|
Randy Read
|
Welcome and introduction |
Fred Dyda
|
Iterative use of site directed mutagenesis to facilitate crystallization:
experiences with integrases |
Jürg Rosenbusch
|
Perspectives in the crystallization of membrane proteins |
Joanne Yeh |
A flash annealing technique to improve diffraction limits and lower mosaicity in crystals of glycerol kinase |
Pushing the limits of data
collection
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Discussion leader: Andrew Leslie
|
Michael
Garavito
|
Multilayer focusing mirrors for the X-ray laboratory: an exciting
new development? |
Steve Ginell
|
Cryocrystallography on extremely bright sources |
Gerd Rosenbaum
|
Third generation undulator synchrotron sources are a crystallographer's
heaven. Is there more life beyond heaven? |
Robert
Sweet
|
Progress in remote operation of synchrotron beamlines: approaching
the FedEx model of data collection |
Marc Whitlow |
Comparison of area detectors |
Crystallography and genomics
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Discussion leader: Tom Terwilliger
|
Sung-Hou Kim
|
Structural genomics: a pilot project |
Andrej Sali
|
Comparative protein structure modeling in genomics |
John Moult
|
Deducing function from structure |
Adventures in phasing I
|
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Discussion leader: Bart Hazes
|
Tom Terwilliger
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SOLVE: Automated MAD/MIR phasing |
Janet Smith
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MAD phasing with large numbers of anomalous scatterers |
Jan Pieter Abrahams
|
The gamma correction beyond solvent flattening: perspectives of bias-free
refinement |
Lynn Ten Eyck
|
Eigenvalue filtering of the full matrix |
Adventures in phasing II
|
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Discussion leader: Michael Chapman
|
Stephen Sheriff |
Implementation of a six-dimensional search using the AMoRe translation function for difficult molecular replacement problems |
Paul Adams |
Extending the limits of molecular replacement through combined simulated annealing and maximum likelihood refinement |
David Smith |
Finding many Se-Met sits with SnB |
Abelardo Silva |
A continuous diffraction intensity function and its implications for phase determination |
New tools for fitting and
refinement
|
Discussion leader: Titia Sixma
|
Axel Brünger |
Crystallography and NMR System: A highly automated and flexible approach
to MAD/MIR/MR phasing and refinement |
Navraj Pannu |
Recent advances in maximum likelihood structure refinement |
Anastassis Perrakis |
wARP: automated procedures for density modification, phase extension and model building |
Tom Oldfield |
Automated electron density tracing and fitting |
Beyond single crystal X-ray
diffraction
|
|
Discussion leader: Janet Smith |
Andrew Leslie |
An application of cryo-electron microscopy imaging to X-ray structure
determination: The 3.6A resolution structure solution of Hepatitis B virus
core particle |
Michael
Wall |
Making sense of diffuse scattering and making use of all the X-rays |
Gerald
Stubbs |
Refinement in macromolecular fiber diffraction: lessons from
the filamentous viruses |
Extreme crystallography
|
Discussion leader: Jan Pieter Abrahams |
Rick Bott |
Pushing back the envelope of resolution, and what you see when you do |
Elizabeth Getzoff |
Time-resolved crystallography |
Nenad Ban |
A 9Å resolution X-ray crystallographis map of the large ribosomal subunit |
Modeling and analysis
|
|
Discussion leader: Jan Pieter Abrahams
|
Amy Anderson |
Targeting HIV opportunistic infections using rational drug design |
Jonathan Friedman |
Computational prediction and experimental verification of unanticipated physiological ligands for proteins |
Keynote address
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|
Randy Read & Andrew Howard, Chairs |
Business meeting |
Michael Rossmann |
The next era in structural biology |