| SUNDAY |
| 2:00 pm - 11:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Membrane Proteins and Complexes |
| Discussion Leader: Andrew Leslie (LMB, Medical Research Council, Cambridge) |
| 7:30 pm - 8:20 pm | Peter Kuhn (Scripps Research Institute, California)
"Structure determination of membrane proteins" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:20 pm | Jamie Cate (UC Berkeley, California)
"The structure of the 70S ribosome at 3.5 Angstrom resolution" |
| 9:20 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Data Collection and Processing |
| Discussion Leader: Nicholas Sauter (Lawrence Berkeley National Laboratory) |
| 9:00 am - 9:35 am | Olof Svensson (ERSF, France)
"Automated data analysis and collection with DNA" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am | Coffee Break / Group Photo (10:00 am) |
| 10:15 am - 10:50 am | Raimond Ravelli (EMBL-ERSF, France)
"Detection and application of radiation damage" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 11:35 am | Ana Gonzalez (SSRL, California)
"Beamline automation at the Stanford Synchrotron Radiation Laboratory" |
| 11:35 am - 11:45 am | Discussion |
| 11:45 am - 12:20 pm | Zbyszek Otwinowski (University of Texas South Western, Texas)
"The propagation of errors from data collection through to structure solution" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Complementary Biophysical Methods |
| Discussion Leader: Elspeth Garman (Oxford University, England) |
| 7:30 pm - 8:00 pm | Laurence Barron (University of Glasgow, Scotland)
"Raman optical activity: a new method for structure analysis of proteins and viruses" |
| 8:00 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:40 pm | Jim McDonnell (Oxford University, England)
"Combining different structural and biophysical methods" |
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | Hiro Tsuruta (SSRL, California)
"Small-angle X-ray scattering" |
| 9:20 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Computational Methods |
| Discussion Leader: Ralf Grosse-Kunstleve (Lawrence Berkeley National Laboratory) |
| 9:00 am - 9:35 am | Michael Chapman (Florida State University, Tallahassee)
“NCS and Bias in free R-factors” |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10.20 am | Airlie McCoy (Cambridge University, England)
“Phasing with Phaser” |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:35 am | Paul Emsley (University of York, England)
“Model building and more with COOT” |
| 11:35 am - 11:45 am | Discussion |
| 11:45 am - 12:20 pm | Thomas Schneider (FIRC Institute of Molecular Oncology, Milano)
“Detecting and Exploiting Structural Variability” |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Electrons and Neutrons |
| Discussion Leader: Bill Massover (New Jersey Medical School) |
| 7:30 pm - 8:00 pm | Wah Chiu (Baylor College of Medicine)
"Cryo-electron microscopy of biological assemblies" |
| 8:00 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:40 pm | Ken Downing (Lawrence Berkeley National Laboratory)
"Electron diffraction studies of tubulin and cancer drugs" |
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | Paul Langan (Los Alamos National Laboratory)
"Neutron diffraction" |
| 9:20 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Difficult Structures |
| Discussion Leaders: Karin Reinisch (Yale University) & David Rodgers (University of Kentucky) |
| 9:00 am - 9:35 am | Timm Maier (ETH, Switzerland)
"Structural basis of eukaryotic fatty acid synthesis" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10.20 am | Gloria Borgstahl (University of Nebraska Medical Center)
"Structural studies of the modulated semi-crystalline state of profilin:actin" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:35 am | Jennifer Doudna (UC Berkeley, California)
"Structural studies of RNA molecules and their protein partners" |
| 11:35 am - 11:45 am | Discussion |
| 11:45 am - 12:20 pm | Olga Mayans (Biozentrum, University of Basel, Switzerland)
"Structural analysis of poly-Ig fragments from the muscle protein titin" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | Advances in Structure Refinement |
| Discussion Leader: Eleanor Dodson (University of York, England) |
| 7:30 pm - 8:00 pm | Gerard Bricogne (Global Phasing Ltd., Cambridge, England)
"Structure refinement with BUSTER" |
| 8:00 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:40 pm | Garib Murshudov (University of York, England)
"Recent advances in REFMAC" |
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | TBA |
| 9:20 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:15 am | Oral Presentations of Selected Posters |
| Discussion Leader: TBA |
| 9:00 am - 10:15 am | 15 minute presentations |
| 10:15 am | Coffee Break |
| 10:45 am - 12:30 pm | Structure Completion |
| Discussion Leader: Jane Richardson (Duke University) |
| 10:45 am - 11:25 am | Tom Terwilliger (Los Alamos National Laboratory)
"Finishing a structure: full-omit maps, multiple model representations, and ligand identification" |
| 11:25 am - 11:35 am | Discussion |
| 11:35 am - 12:15 pm | Tassos Perrakis (NKI, Amsterdam, The Netherlands)
"Model completion in ARP/wARP" |
| 12:15 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Tomographic and Diffractive Imaging Methods |
| Discussion Leader: Gerry McDermott (University of California, San Francisco) |
| 7:30 pm - 8:20 pm | Grant Jensen (Caltech, California)
“Electron cryo-tomography of purified protein complexes, viruses, and small cells” |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:20 pm | Chris Jacobsen (SUNY, Stonybrook)
"Diffractive imaging methods applied to biological materials" |
| 9:20 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
