| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session |
| Discussion Leaders: Christopher Williams (Duke University) and Gary Gilliland (Janssen Research & Development) |
| 3:45 pm - 4:15 pm | John Kuriyan (UC Berkeley)
"Structural Analysis of Signal Transduction Proteins"
|
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Upcoming Techniques in Structural Biology |
| Discussion Leaders: Iris Young (Lawrence Berkeley National Lab) and Elspeth Garman (University of Oxford) |
| 7:30 pm - 7:45 pm | Aaron Brewster (Lawrence Berkeley National Laboratory)
"Indexing Amyloid Peptide Diffraction from Serial Femtosecond Crystallography: New Algorithms for Sparse Patterns"
|
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Monarin Uervirojnangkoorn (Stanford University)
"Post-Refinement and Its Impact on Merged XFEL Data"
|
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Daniel Keedy (University of California)
"Discovering Coupled Conformational Heterogeneity in Proteins by Multi-Temperature Crystallography"
|
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Andrew Malaby (UMass Medical School)
"Size Exclusion Chromatography SAXS to Assess Multimeric and Allosteric States for GTPase Regulatory Proteins"
|
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Bradley Hintze (Duke University)
"Hidden Hogsteens in the Data"
|
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Raymond Sierra (Stanford PULSE Institute)
"Sample Characterization and In-Vacuo Delivery of Protein Crystals for Serial Femtosecond Crystallography Studies"
|
| 9:25 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Overcoming Challenges in Structure Determination - Integrative Approaches and Complementary Methods |
| Discussion Leaders: Henrike Mueller-Werkmeister (University of Toronto) and John Kuriyan (UC Berkeley) |
| 9:00 am - 9:15 am | Pawel Janowski (Rutgers University)
"Crystallographic Refinement in Phenix with the Amber Molecular Mechanics Force Field"
|
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Oleg Sobolev (Lawrence Berkeley National Laboratory)
"Extending Phenix Tools for Low-Resolution Refinement Against Crystallographic and EM Data"
|
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | Lina Malinauskaite (Aarhus University)
"New Insights into the Transport Mechanism of the NSS Family"
|
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Ivan Campeotto (Imperial College London)
"Structural and Mechanistic Insight into the Listeria monocytogenes Two-Enzyme Lipoteichoic Acid Synthesis System"
|
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Anna Polyakova (University of Leeds)
"The Ins-and-Out of a Membrane Protein: The Transport Mechanism of Mhp1 by Complementary Structural Techniques"
|
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Richard Gildea (Diamond Light Source)
"New Methods for Indexing Multi-Lattice Diffraction Data"
|
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Beyond Graduate School: Academia vs. Industry |
| A Career Panel Featuring Mentors from both Academia and Industry |
| Discussion Leader: Jonathan Brooks-Bartlett (University of Oxford) |
| Mentors:
- Elspeth Garman (University of Oxford)
- Gary Gilliland (Janssen Research & Development)
- John Kuriyan (UC Berkeley)
|
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
