Uncovering Complexity in Drug Metabolism in the Cell and the Clinic

The 48th Drug Metabolism Gordon Research Conference will focus on cutting edge research in drug ADME (absorption, distribution, metabolism, elimination), encompassing a wide range of research from the cellular level to the patient. Complexity in biological systems and enzymatic processes is continually uncovered in science. The conference aims to illuminate this biological complexity, often studied with simple biological and mathematical models, in order to enhance the application of new knowledge to understanding drug safety and efficacy in the clinic. The 2018 conference will include a keynote presentation on understanding drug toxicity, and scientific sessions on structure/function of drug metabolizing enzymes, interactions between the cell membrane and enzyme/transporter proteins, drug-drug interactions and toxicity, modeling drug metabolism and transport, drug disposition and toxicity in special (pediatric, understudied, and disease) populations, and case studies based on regulatory guidances. All presentations will include unpublished data, with sessions designed for maximal audience discussion. Attendees are encouraged to submit posters for presentation at the poster session organized by the Vice Chair Dr. Griff Humphreys. The Wednesday evening session will feature oral presentations by young investigators (graduate students and postdoctoral trainees) selected from the submitted poster abstracts. The conference is collegial and informal in nature, with ample opportunity to discuss unpublished research, make collaborative connections, and develop new ideas. Young investigators have easy access to individual mentoring from established investigators, as well as during career advice sessions planned during the week.

The registration fee includes all meals and housing on the Holderness School campus. In addition to the scientific sessions, attendees are strongly encouraged to enjoy the many outdoor recreational activities in the New Hampshire area. Afternoon traditions of this conference include an Academia vs. Industry softball game (no experience necessary, bring your gloves!), and hiking and kayaking/canoeing outings in the White Mountains.