Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Endothelial Cell Specification and Angiogenesis
7:40 pm - 8:00 pm
Introduction by Discussion Leader
8:00 pm - 8:20 pm
"Regulation of Endothelial Cell Specialization"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Controlling Lymphatic Vascular Growth and Fate"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Breaking Symmetry in Vascular Networks"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Endothelial Phenotypes Underlying Central Nervous System Health and Disease
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"Essential Fatty Acid Transport Across Blood-Brain Barrier Endothelium"
9:35 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Mechanisms Underlying Cerebrovascular Adaptation in Brain Diseases"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"VEGFB in the Storm or Drought of Angiogenesis"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Targeting Endothelial Senescence in Retinopathies"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Novel VE-Cadherin Regulators in Endothelial Adherens Junctions"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Endothelial Diversity in Cerebral Cavernous Malformations"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Endothelial Phentoypes Underlying Infection, Respiratory Distress and Sepsis
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:35 pm
"Endothelial Glycocalyx Degradation During Sepsis: Lessons From Randomized, Controlled Human Trials"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Endogenous NO Inhibitors: Biology, Pathology, Therapeutic Potential"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Loss of ERG Function Contributes to Primary Lymphoedema"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Mechanisms Governing Endothelial Barrier Permeability"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Endothelial Roles in Metabolic and Lymphatic Disorders
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"Endothelial Regulation of Adipose Tissue Function"
9:35 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Spatio-Temporal Control of Lymphatic Endothelial Cell Proliferation"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"A New Regulator of Metabolism"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Molecular Regulation of Endothelial Cell Metabolism and Function"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Impact of Obesity on Blood Vessels"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Endothelial Metabolism in Metabolic Syndrome"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Endothelial Phenotypes in Vascular Development, Ageing and Regeneration
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:35 pm
"The Ageing Endothelium in Alzheimer’s Disease"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"Senescent Endothelium in Doxorubicin-Induced Cardiotoxicity Sustains Inflammation Via Mitochondrial DNA Synthesis"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Angiocrine Signal Diversity in Liver Regeneration and Non-Alcoholic Fatty Liver Disease"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Regulation of Lymphatic Junctional Integrity by ZEB1"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Dynamic Endothelial Behavior and Extracellular Matrix Remodeling in Sprouting Angiogenesis"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Sex Differences in Cardiovascular Disease
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"Sex Differences in Ageing of Blood Vessels"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Sex Dimorphic Endothelial Cell Phenotypes in Adipose Tissue"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"FOXO1 Regulates Cellular Homeostasis in Female Adipose Endothelium"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Sex Differences in Endothelial Cells Originating From Atherosclerotic Plaques"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Sex Differences in Peripheral Artery Disease"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"The Role of Enothelial Liver X Receptors in Atherosclerosis"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Transcriptional and Epigenetic Regulation of EC Phenotypes
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:35 pm
"Transcriptional Regulation of Capillary Regression"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"Nuclear SUN2 Regulates Endothelial Flow Responses and Barrier Function Via Cell-Matrix Interactions"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Endothelial Progenitor Reprogramming and Transformation Into Myogenic Rhabdomyosarcoma Mediated by PAX3-FOXO1"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Transcriptional Isoforms Impact on Cellfate, Functions & Genetic Contribution to Disease"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"A Novel Regulatory Circuit Required for Tumor Angiogenesis and Cancer Growth"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Bioengineering and Big Data
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"Vascular Complexity Loci in Retina and Myocardial Infarction"
9:35 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Endothelial Changes in the Vascular Wall Preceding the Onset of Aortic Dissection at Single-Cell Resolution"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Optimized Drug Combinations and Vascular Anergy in Cancer Treatment"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"State Transition Analysis of ECs: Causal Networks in Disease and Health"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Understanding Vascularization and Vessel Remodelling Using Explainable Machine Learning"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Engineering Vascular Networks In Vitro and In Vivo"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Endothelial Interactions with Haematopoiesis and Inflammation
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:35 pm
"Endothelial Modulation of Cardiac Remodeling in Heart Failure"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Endothelial S1P and Immune Cross Talk in Volumetric Muscle Loss"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Angiocrine Control of Epidermal Stratification"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Innate Immunity of Endothelium"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure