Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Human Exposure and Health Consequences of Environmental Endocrine Disruptors
7:40 pm - 8:15 pm
"EDCs Target Prostate Stem-Progenitor Cells Through Chemical-Specific Mechanisms"
8:15 pm - 8:35 pm
Discussion
8:35 pm - 9:10 pm
"Human Exposure to EDCs: Some Lessons Learned"
9:10 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Mechanisms of Environmental Endocrine Disruptor Action
9:00 am - 9:25 am
"What Structural Biology Tells Us about the Mode of Action and Detection of Endocrine Disruptors"
9:25 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Exploring the Impact of EDCs and Sex-Hormones on hESC-Derived Thyroid Follicles Using Single Cell Transcriptomics"
10:05 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Combining Multi-Behavioral Phenotyping and Neurotoxicity Fingerprints for the Identification of Chemical Mode of Action in Early Life Stage Zebrafish"
11:15 am - 11:30 am
Discussion
11:30 am - 11:55 am
"Using Omics Studies and Metabolic Network Analysis for the Exploration of the Metabolic Effects of EDCs: Opportunities, Pitfalls and Challenges"
11:55 am - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Cellular and Molecular Mechanisms Underlying the Disruption of Sexual Behavior in Female Mice Exposed to Environmentally Relevant Doses of Phthalates."
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Characterizing Human Exposure to Environmental Endocrine Disruptors
6:00 pm - 6:25 pm
"Assessing Impacts of the Chemical Exposome on Child Growth and Metabolic Risk"
6:25 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
"Novel Strategies to Assess Risks Associated with Human Relevant Mixtures"
7:05 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
"Human Exposure to Plastic Chemicals: Bottom-Up Approaches"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Integrating Human and Environmental Health Research
9:00 am - 9:25 am
"Cross-Species Applicability of an AOP Network for Thyroid Hormone System Disruption as a Basis for Harmonized IATA Development"
9:25 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Defining Adverse Effects of PFAS Exposure: A Community Engaged One Health Approach"
10:05 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Thyroid Disruption and Beyond: Linking Experimental and Human Observations for EDCs"
11:15 am - 11:30 am
Discussion
11:30 am - 11:45 am
"Novel Approach for the Identification of Endocrine Disrupting Compounds in Complex Exposure Mixtures"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Intrauterine Exposure to the Organochlorine Pesticide p,p’-DDE Disrupts the Hypothalamus-Pituitary-Thyroid Axis Function of the Offspring Rats During Adulthood"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Heavy Metals in African Wildlife: The Influence of Diet and Foraging Behaviour"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Environmental Endocrine Disruptors-Mediated Effects on Development and Reproduction
6:00 pm - 6:25 pm
"Transgenerational Disruption of the Hypothalamic Control of Reproduction and Energy Balance"
6:25 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
"Early Exposures and the Human Minipuberty"
7:05 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
"Improving the Identification of Endocrine Disruptors Causing Reproductive Disorders"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Environmental Endocrine Disruptors and Metabolic Disorders
9:00 am - 9:25 am
"Development of an Integrated Approach for Comprehensive Assessment of Metabolism Disrupting Chemicals: The GOLIATH Project"
9:25 am - 9:40 am
Discussion
9:40 am - 10:05 am
"The Impact of Persistent Pollutants on Pancreatic Islets"
10:05 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Developmental Paternal Line and Maternal Line Environmental Correlates of Obesity in a Three Generation Pregnancy Cohort: New Exposome and Metabolome Evidence from The Child Health and Development Studies"
11:15 am - 11:30 am
Discussion
11:30 am - 11:55 am
"Heritable Changes in Chromatin Contacts Linked to Transgenerational Obesity"
11:55 am - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Molecular Insight into EDC-Induced Adult-Onset and Transgenerational Inheritance of Disease Using the Zebrafish Model"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Environmental Endocrine Disruptors and Developmental Neurotoxicity
6:00 pm - 6:25 pm
"Sculpting the Future: How GnRH Neurons Shape Neuroglial Environments for Sexual Maturation and Fertility, and the Impact of Endocrine Disruptors"
6:25 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
"Novel Pathways Linking Endocrine Disruption to Developmental Neurotoxicity: Insights from the ENDpoiNTs Project"
7:05 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
"Thyroid Disruption in Pregnancy: New Pathways and its Role for Fetal Neurodevelopment"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Multi-Stakeholder Perspectives on the Environmental ED Field
9:00 am - 9:25 am
"Novel Testing Strategies for Endocrine Disruptors: Collectively Building Pathways to Regulatory Acceptance"
9:25 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Plastics, Endocrine Disrupting Chemicals and Health: Towards a Legally Binding Instrument to End Plastic Pollution"
10:05 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Working at the Science-Policy Interface: the Case of Food Contact Chemicals"
11:15 am - 11:30 am
Discussion
11:30 am - 11:45 am
"Per- and Polyfluoroalkylated Substances (PFAS) Modes of Action and Effects"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Improving Risk Assessment One model at a Time: New Data for the Toxicology of the Mammary Gland"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Assessment of Endocrine Disruption of Pesticides Active Substances: Status and Regulatory Experience"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Planetary Health: Global Solutions for Global Problems
6:00 pm - 6:25 pm
"Endocrine Disrupting Chemicals in Africa - Where Are We Now?"
6:25 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
"Leveraging Commitments from the EU Green Deal for Improved Protection Against EDCs"
7:05 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
"Beyond Wingspread: The Case for a Planetary Health Perspective on Endocrine Disruption"
7:45 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure