Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: Navigating the Evolving Field of Environmental Endocrine Disruptors
Discussion Leader: Angel Nadal (Miguel Hernandez University of Elche, Spain)
3:15 pm - 3:50 pm
Terje Svingen (Technical University of Denmark, Denmark)
"Navigating the Evolving Field of EDCs: A Reproductive Toxicologist’s Viewpoint"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Diverse Targets of Environmental Endocrine Disruptors
Discussion Leaders: Samantha Heldman (Wayne State University, United States) and Mallory Llewellyn (University of Florida, United States)
5:30 pm - 5:40 pm
KONSTANTINA TSINTSIFAS (University of Illinois - Chicago, United States)
"Persistent Organic Pollutants and Diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
Molly McPartland (Norwegian University of Science and Technology, Norway)
"Understanding Mechanisms of Circadian Rhythm Disruption by Chemicals in Plastic Food Packaging"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:10 pm
Devon Guerrelli (Children's National Hospital, United States)
"Plastic Chemicals and Cardiac Surgery – Evaluating the Extent of Exposure and the Efficacy of Mitigation Strategies"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
Stephanie Martinez (New Jersey Institute of Technology, United States)
"Mixtures of Phthalates Disrupt Expression of Genes Related to Lipid Metabolism and Peroxisome Proliferator-Activated Receptor Signaling in Mouse Granulosa Cells"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Brittney Williams (University of Kentucky, United States)
"Ovulatory Angiogenic Factors and Receptors are Altered by an Environmentally Relevant Phthalate Mixture in Mouse Granulosa and Endothelial Cells In Vitro "
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Katie Land (University of Kentucky, United States)
"Exposure to Phthalates Disrupts Ovulatory Luteinizing Hormone/Choriogonadotropin Receptor Signaling and Decreases Downstream Prostaglandin Production in Human Granulosa Cells In Vitro "
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
Jillian Poska (The Ohio State University, United States)
"In Utero Exposure to Estrogenic Bisphenol Compounds Affects The Mammary Gland Microenvironment"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Sarah Stucchi (Human Technopole, Italy)
"From Pluripotency to Germ Cells and Back: Modeling the Molecular Impact of Endocrine Disruptors on Intergenerational Inheritance and Human Neurodevelopment in A Dish"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Developing New Approach Methodologies
Discussion Leaders: Juliette Legler (Utrecht University, The Netherlands) and Nicky Byers (Karolinska Institutet, Sweden)
9:00 am - 9:10 am
Ah-Reum Jo (Seoul National University, South Korea)
"Thyroid hormone disruption by UV filter mixtures in sunscreen products: Observations in GH3 cells and zebrafish larvae"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
David Lopez Rodriguez (University of Lausanne, Switzerland)
"A Machine Learning Framework for Identifying and Prioritizing the Risk Assessment of Endocrine Disrupting Chemicals (EDCs)"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Roxanne Berube (Wayne State University, United States)
"Organic and Inorganic Contaminants and Mixtures Disrupt Metabolic Health, Neurodevelopment and Gene Expression in Developmentally Exposed Zebrafish"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Sara KASSIR (Inserm U1211, France)
"Identification of Obesogens using Zebrafish Larvae as a Model"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Neele Wewer (German Federal Institute for Risk Assessment, Germany)
"Development of a Phospholipidosis Assay with Human Liver Cells using High-Throughput Fluorescence Microscopy"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Patrice Delaney (Massachusetts General Hospital, Harvard Medical School, United States)
"Estrogen-Mediated Perturbations in Biliary Endothelial Cells: Implications for Liver Homeostasis and Disease"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Sophie Emilie Bresson (University of Oslo, Norway)
"Persistent Organic Pollutants Disrupt the Oxidant/Antioxidant Balance of Pancreatic ß-Cells Causing Their Physiological Dysfunctions"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Roberto Sempere Navarro (Universidad Miguel Hernández de Elche, Spain)
"The Role of Oestrogen Receptor Beta on K+ Channel Regulation in the Human Beta Cell Line EndoC-ßH1"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Power At The Podium: Increasing The Impact Of Your Scientific Presentations
Discussion Leaders: Christopher Kassotis (Wayne State University, United States) and Nadja Visser (Uppsala University, Sweden)
1:30 pm - 1:40 pm
Kim Nail Cajachagua Torres (New York University Grossman of Medicine, United States)
"Prenatal Exposure to Phthalates and Anogenital Distance at Age 12 Months"
1:40 pm - 1:45 pm
Discussion
1:45 pm - 1:55 pm
Andrea Webster (Mammal Research Institute, University of Pretoria, South Africa, South Africa)
"Heavy Metals in African Wildlife: The Influence of Diet and Foraging Behaviour"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:20 pm
Patricia Hunt (Washington State University, United States)
"Power At the Podium: Increasing the Impact of Your Scientific Presentations"
2:20 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes