Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: Collective Epithelial Dynamics in Intestinal Development
Discussion Leader: Ophir Klein (Cedars-Sinai and University of California San Francisco, United States)
3:15 pm - 3:40 pm
Kaelyn Sumigray (Yale School of Medicine, United States)
"Collective Epithelial Dynamics in Intestinal Development"
3:40 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Development and Regeneration of the Epithelium
Discussion Leader: Jakob Josef Langer (École Polytechnique Fédérale de Lausanne, Switzerland)
5:30 pm - 5:40 pm
Amanda Andersson Rolf (Hubrecht Institute, Netherlands Antilles)
"Long-Term In Vitro Expansion Of A Human Tripotent Fetal Pancreas Progenitor Cell"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
Shicong Xie (Stanford University, United States)
"The Mammalian G1/S Transition Is Autonomously Determined By A Cell Size Homeostasis Mechanism In Vivo"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:10 pm
Çagri Çevrim (Harvard University, United States)
"A New Model of Menstruation and Endometrium Regeneration"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:25 pm
Alejo Torres Cano (King's College, United Kingdom)
"Spatial and Temporal Dynamics of the Pancreatic Mesenchyme During Embryonic Development"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Trevor Isner (Anschutz Medical Campus, University of Colroado, United States)
"SOX9 Marks Stem Cells Upstream of LGR5+ Taste Progenitors in the Mouse Circumvallate Papilla"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Han Chen (Westlake University, China)
"Intermittent Fasting-induced Lipolysis in Niche Adipocytes Drives Apoptosis of Hair Follicle Stem Cells"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
Cailin McMahon (Cornell University, United States)
"Broadening the Hair Follicle Stem Cell Niche: Vasculature Regulation of Stem Cell Activation"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Swarnabh Bhattacharya (Dana-Farber Cancer Institute / Harvard Medical School, United States)
"Unified Identity of Goblet and Paneth Cells and Chromatin Basis for Intestinal Epithelial Differentiation"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Epithelium Dynamics in Disease and Aging
Discussion Leader: Ronja Houtekamer (University Medical Center Utrecht, The Netherlands)
9:00 am - 9:10 am
Viral Shah (Massachusetts General Hospital, United States)
"Airway Hillocks are Injury-Resistant Reservoirs of Rare Plastic Stem Cells"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Mei Lan Li (Yale University, United States)
"Dysregulated Epithelial-Mesenchymal Crosstalk in the Stem Cell Niche as Mechanisms of Intestinal Polyp Formation"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Yiting Xu (Yale University, United States)
"Epigenetic Regulation of Macrophage Activity by Glutamine During Wound Healing"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Amany Ammar (University College London, United Kingdom)
"The Influence of Tobacco Smoking on the Genomic Landscape of Alveolar Stem Cells"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Wenxin Fan (IRCMS, Kumamoto University, Japan)
"The Roles of the Extracellular Matrix, Fibulin-5, in the Regulation of Epidermal Stem Cells During Skin Aging"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Grace Lim (Agency for Science, Technology and Research, Singapore)
"Exploiting AQP5 as a Robust Functional Marker of Gastric Cancer Stem Cells Driving Tumourigenesis in Mice and Humans"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Patricia Centeno (Beatson Institute for Cancer Research, United Kingdom)
"Distinct Basal Progenitor Cell Populations Require Specific Transcription Programs to Unlock Tumour growth."
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Daniela Mayer (reNEW - Novo Nordisk Foundation Center for Stem Cell Medicine, Denmark)
"Genome-Wide CRISPR/Cas9 Screen to Identify Novel Regulators of Colonic Regeneration"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Developing Your Research Community
Discussion Leader: Kara McKinley (Harvard University / Howard Hughes Medical Institute, United States)
1:30 pm - 2:30 pm
Panel Discussion
Developing Your Research Community
Margherita Yayoi Turco (Friedrich Miescher Institute for Biomedical Research, Switzerland)
Senta Georgia (Children's Hospital Los Angeles / University of Southern California, United States)
Kim Jensen (University of Copenhagen, Denmark)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes