Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Synapse Organization and Memory
7:40 pm - 8:20 pm
"Towards a Molecular Logic of Synapse Organization"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Memory Formation in the Stressed Mouse"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Excitatory Synapses in Plasticity of Circuitry
9:00 am - 9:20 am
"Excitatory Synaptic Plasticity Differentiates Neocortical Somatostatin Interneurons"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Excitatory Inputs onto Parvalbumin Interneurons are Toggled on and off in a Circadian Manner"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Oxytocinergic Control of Synaptic Function"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Visual Deprivation Induces Non-Homeostatic, Presynaptic Plasticity at Thalamocortical Synapses"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hourâ„¢ is open to all conference participants.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Excitatory Synaptic Molecules in Signaling and Plasticity
7:30 pm - 7:50 pm
"Regulation of NMDA Receptor Trafficking in Homeostatic Synaptic Plasticity"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Role of GluN2D-Containing NMDA Receptors in Synaptic Plasticity and Learning"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"GluN3A Glycine Receptors in Brain Signaling"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Regulation of NMDA Receptor Expression and Targeting: Insights from Rare Variants"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Dynamics of Molecules at Excitatory Synapses
9:00 am - 9:20 am
"Role of AMPAR Nanoscale Dynamics in Synaptic Plasticities"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Regulation of AMPA Receptors in Health and Disease"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Mechanisms of Activity-Driven Remodeling of Scaffolding Nanodomains in the Postsynaptic Density"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Postsynaptic GPCR-Kinase/Phosphatase Signaling Networks in Amyloid Beta-Induced Synaptic Dysfunction"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Session in Memory of Peter Seeburg: Excitatory Synapses in Learning and Memory
7:30 pm - 7:50 pm
"Reorganization of M1 Network During Motor Skill Learning"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"The Leitmotif of GABAergic Projection Neuron Connectivity: Selective Wiring that Supports Disinhibition in the Target Area"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Liquid-Liquid Phase Separation of CaMKII Associated Proteins"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Excitatory Synapses in Disorders and Diseases
9:00 am - 9:20 am
"Synaptic Signaling and Excitotoxicity in Prion Disease"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Decoding BDNF Signaling Pathways in Axonal Transport: From Local Protein Synthesis to CREB Mediated Dendritic Plasticity"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Synaptic Mechanisms of Sensory Cortical Circuit Hyperexcitability in a Mouse Model of Fragile X Syndrome"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Microglia and Oligodendrocyte Precursor Cells Meet at the Synapse"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Excitatory Synapses in the Human Brain
7:30 pm - 7:50 pm
"Human-Specific Activity-Dependent Regulation of Synapses"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Constructing and Deconstructing the Human Nervous System to Study Development and Disease"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Neurophysiology of Brain Organoids"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Disease-Specific Impacts of NRXN1 Deletions on Cortical Synaptic Function and Plasticity in Human iPSC-Derived Neural Cells"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Unconventional Roles of Excitatory Synapses
9:00 am - 9:20 am
"Excitatory Neuron-to-Glioma Synapses in Brain Cancers"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Glial TNF Regulates Synaptic Strength to Alter Anxiety and Reward"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Specialized Glutamatergic Astrocytes and Their Roles in Brain Function and Dysfunction"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Unraveling Non-Canonical Synaptic Functions via Glutamate Receptors"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
New Tools and Ideas for Excitatory Synapses
7:30 pm - 7:50 pm
"Imaging Intracellular Signaling to Multiple Neuromodulators at Subcellular Resolution In Vivo"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"The Synaptome Architecture of the Human Brain"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Optogenetic Approaches to Modulate Calcium Signaling in Vivo"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Decoding Biochemical Signaling Dynamics with Optical Sensors and Actuators"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure